4,470 research outputs found

    Symmetry, Entropy, Diversity and (why not?) Quantum Statistics in Society

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    We describe society as a nonequilibrium probabilistic system: N individuals occupy W resource states in it and produce entropy S over definite time periods. Resulting thermodynamics is however unusual because a second entropy, H, measures a typically social feature, inequality or diversity in the distribution of available resources. A symmetry phase transition takes place at Gini values 1/3, where realistic distributions become asymmetric. Four constraints act on S: expectedly, N and W, and new ones, diversity and interactions between individuals; the latter result from the two coordinates of a single point in the data, the peak. The occupation number of a job is either zero or one, suggesting Fermi-Dirac statistics for employment. Contrariwise, an indefinite nujmber of individuals can occupy a state defined as a quantile of income or of age, so Bose-Einstein statistics may be required. Indistinguishability rather than anonymity of individuals and resources is thus needed. Interactions between individuals define define classes of equivalence that happen to coincide with acceptable definitions of social classes or periods in human life. The entropy S is non-extensive and obtainable from data. Theoretical laws are compared to data in four different cases of economical or physiological diversity. Acceptable fits are found for all of them.Comment: 13 pages, 2 figure

    Electrical Nanoprobing of Semiconducting Carbon Nanotubes using an Atomic Force Microscope

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    We use an Atomic Force Microscope (AFM) tip to locally probe the electronic properties of semiconducting carbon nanotube transistors. A gold-coated AFM tip serves as a voltage or current probe in three-probe measurement setup. Using the tip as a movable current probe, we investigate the scaling of the device properties with channel length. Using the tip as a voltage probe, we study the properties of the contacts. We find that Au makes an excellent contact in the p-region, with no Schottky barrier. In the n-region large contact resistances were found which dominate the transport properties.Comment: 4 pages, 5 figure

    Isotropic, Nematic and Smectic A Phase Behaviour in a Fictitious Field

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    Phase behaviours of liquid crystals under external fields, conjugate to the nematic order and smectic order, are studied within the framework of mean field approximation developed by McMillan. It is found that phase diagrams, of temperature vs interaction parameter of smectic A order, show several topologically different types caused by the external fields. The influences of the field conjugate to the smectic A phase, which is fictitious field, are precisely discussed.Comment: To be published in J. Phys. Soc. Jpn. vol.73 No.

    State Differentiation by Transient Truncation in Coupled Threshold Dynamics

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    Dynamics with a threshold input--output relation commonly exist in gene, signal-transduction, and neural networks. Coupled dynamical systems of such threshold elements are investigated, in an effort to find differentiation of elements induced by the interaction. Through global diffusive coupling, novel states are found to be generated that are not the original attractor of single-element threshold dynamics, but are sustained through the interaction with the elements located at the original attractor. This stabilization of the novel state(s) is not related to symmetry breaking, but is explained as the truncation of transient trajectories to the original attractor due to the coupling. Single-element dynamics with winding transient trajectories located at a low-dimensional manifold and having turning points are shown to be essential to the generation of such novel state(s) in a coupled system. Universality of this mechanism for the novel state generation and its relevance to biological cell differentiation are briefly discussed.Comment: 8 pages. Phys. Rev. E. in pres

    Gene identification for the cblD defect of vitamin B12 metabolism

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    Background Vitamin B12 (cobalamin) is an essential cofactor in several metabolic pathways. Intracellular conversion of cobalamin to its two coenzymes, adenosylcobalamin in mitochondria and methylcobalamin in the cytoplasm, is necessary for the homeostasis of methylmalonic acid and homocysteine. Nine defects of intracellular cobalamin metabolism have been defined by means of somatic complementation analysis. One of these defects, the cblD defect, can cause isolated methylmalonic aciduria, isolated homocystinuria, or both. Affected persons present with multisystem clinical abnormalities, including developmental, hematologic, neurologic, and metabolic findings. The gene responsible for the cblD defect has not been identified. Methods We studied seven patients with the cblD defect, and skin fibroblasts from each were investigated in cell culture. Microcell-mediated chromosome transfer and refined genetic mapping were used to localize the responsible gene. This gene was transfected into cblD fibroblasts to test for the rescue of adenosylcobalamin and methylcobalamin synthesis. Results The cblD gene was localized to human chromosome 2q23.2, and a candidate gene, designated MMADHC (methylmalonic aciduria, cblD type, and homocystinuria), was identified in this region. Transfection of wild-type MMADHC rescued the cellular phenotype, and the functional importance of mutant alleles was shown by means of transfection with mutant constructs. The predicted MMADHC protein has sequence homology with a bacterial ATP-binding cassette transporter and contains a putative cobalamin binding motif and a putative mitochondrial targeting sequence. Conclusions Mutations in a gene we designated MMADHC are responsible for the cblD defect in vitamin B12 metabolism. Various mutations are associated with each of the three biochemical phenotypes of the disorder

    Generation of measures on the torus with good sequences of integers

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    Let S=(s1<s2<)S= (s_1<s_2<\dots) be a strictly increasing sequence of positive integers and denote e(β)=e2πiβ\mathbf{e}(\beta)=\mathrm{e}^{2\pi i \beta}. We say SS is good if for every real α\alpha the limit limN1NnNe(snα)\lim_N \frac1N\sum_{n\le N} \mathbf{e}(s_n\alpha) exists. By the Riesz representation theorem, a sequence SS is good iff for every real α\alpha the sequence (snα)(s_n\alpha) possesses an asymptotic distribution modulo 1. Another characterization of a good sequence follows from the spectral theorem: the sequence SS is good iff in any probability measure preserving system (X,m,T)(X,\mathbf{m},T) the limit limN1NnNf(Tsnx)\lim_N \frac1N\sum_{n\le N}f\left(T^{s_n}x\right) exists in L2L^2-norm for fL2(X)f\in L^2(X). Of these three characterization of a good set, the one about limit measures is the most suitable for us, and we are interested in finding out what the limit measure μS,α=limN1NnNδsnα\mu_{S,\alpha}= \lim_N\frac1N\sum_{n\le N} \delta_{s_n\alpha} on the torus can be. In this first paper on the subject, we investigate the case of a single irrational α\alpha. We show that if SS is a good set then for every irrational α\alpha the limit measure μS,α\mu_{S,\alpha} must be a continuous Borel probability measure. Using random methods, we show that the limit measure μS,α\mu_{S,\alpha} can be any measure which is absolutely continuous with respect to the Haar-Lebesgue probability measure on the torus. On the other hand, if ν\nu is the uniform probability measure supported on the Cantor set, there are some irrational α\alpha so that for no good sequence SS can we have the limit measure μS,α\mu_{S,\alpha} equal ν\nu. We leave open the question whether for any continuous Borel probability measure ν\nu on the torus there is an irrational α\alpha and a good sequence SS so that μS,α=ν\mu_{S,\alpha}=\nu.Comment: 44 page
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