Additional file 1: Table S1. of Changes in selected metabolic parameters in patients over 65 receiving hydrochlorothiazide plus amiloride, atenolol or placebo in the MRC elderly trial

Mean (SD) of outcome variables over time (all groups combined). (DOCX 12 kb

The confounding effect of smoking on the association between maternal age and adverse pregnancy outcome.

<p>^aAdjusted for , parity, maternal BMI, social deprivation score and ethnicity; Highlighted estimates indicate a significant interaction test with p<0.05. <b>VSGA</b> (Very small-for-gestational age, <5^th percentile); <b>VLGA</b> (Very-large-for-gestational age, >95^th percentile).</p

Relative risks of pregnancy outcome and maternal age according to social deprivation group.

<p>^aAdjusted for , parity, maternal BMI, parity and ethnicity; Highlighted estimates indicate a significant interaction test with p<0.05. <b>VSGA</b> (Very small-for-gestational age, <5^th percentile); <b>VLGA</b> (Very-large-for-gestational age, >95^th percentile).</p

Crude and adjusted relative risks of the association between maternal age and adverse pregnancy outcome.

<p>^aAdjusted for , parity, maternal BMI, social deprivation score and ethnic origin;</p>b<p>model based on 2007–2008 data only. <b>ESGA</b> (Extremely small-for-gestational age, <3^rd percentile); <b>VSGA</b> (Very small-for-gestational age, <5^th percentile); <b>SGA</b> (Small-for-gestational age, <10^th percentile); <b>LGA</b> (Large-for-gestational age, >90^th percentile); <b>VLGA</b> (Very-large-for-gestational age, >95^th percentile); <b>ELGA</b> (Extremely-large-for-gestational-age, >97^th percentile).</p

Number of births, inclusions and exclusions during the study period.

<p>Number of births, inclusions and exclusions during the study period.</p

Relative risks of pregnancy outcome and maternal age according to parity.

<p>^aAdjusted for , parity, maternal BMI, social deprivation score and ethnicity; Highlighted estimates indicate a significant interaction test with p<0.05. <b>VSGA</b> (Very small-for-gestational age, <5^th percentile); <b>VLGA</b> (Very-large-for-gestational age, >95^th percentile).</p

Maternal characteristics and pregnancy outcome in relation to maternal age.

<p>Data refers to <b>N (%).</b><b>*Birth weight</b><b>ESGA</b> (Extremely small-for-gestational age, <3^rd percentile); <b>VSGA</b> (Very small-for-gestational age, <5^th percentile); <b>SGA</b> (Small-for-gestational age, <10^th percentile); <b>LGA</b> (Large-for-gestational age, >90^th percentile); <b>VLGA</b> (Very-large-for-gestational age, >95^th percentile); <b>ELGA</b> (Extremely-large-for-gestational-age, >97^th percentile).</p