Papillon-lefèvre syndrome: A case report

Takayasu's arteritis (TA) is a major chronic vasculitis disorder that its etiology is unknown. Patients are mostly Asian women who often show nonspecific symptoms such as fever, myalgia, arthralgia, weight loss, and anemia. The report relates to a 17-year-old girl suffering from complaints, permanent and uncontinental pain starting from a month earlier, with loss of appetite and weight loss (4 kg), and night sweats. She had no diarrhea or gastrointestinal symptoms but had a pain in the shoulder and chest area since the last 5 months. She got better after seeing a physician and receiving supplements. She had a history of pain in the ear from the last five months leading to otitis, and was treated as a case of brucellosis with a score of 1.20 in the Coombs Wright test. According to the physical examination findings, the patient's left, radial, ulnar, and proximal pulses, and blood pressure were unexplained, and in the supraclavicular region of the left and the umbilical region, bruit was heard and the shape of the left nail was changed. Laboratory tests and imaging were performed for the patient, and after angiography, the left subclavian artery stenosis was detected. Given the age and sex of the patient and the results obtained, she was diagnosed with Takayasu's arteritis. © 2021, Kerman University of Medical Sciences. All rights reserved

Detection of tooth decay: Report of a novel invention

Tooth decay is a microbial infectious disease that caused to local damage of calcification tissues of tooth and common cause of tooth damage in youth. Therefore, prevention of this damage is necessary. One of the most important methods of prevention of tooth decay is opportune diagnosis of decay and reconstruction. The present study aimed to introduce a novel invention for early diagnosis of tooth decay and to compare result of experiment of this device with other common methods. This device will diagnose tooth decay without any chemicals and rays such as lasers or X-rays. It works by shining infrared light reflected on the surface of the tooth. It will be placed on the tooth and Transmitting infrared light will be reflected on the surface of the tooth and Infrared sensor receives light from the tooth surface. All lights are reflected, but if the tooth was rotten, then its color would be darker and the reflected light would be absorbed on the surface of the teeth. The rest of the light is reflected. By the difference between the amount of light reflected from the surface of decayed teeth and Healthy Teeth the device is able to detect decay and dental health. Infrared sensor is a type of optical transistors. When the light is shone on them, the light will be converted into an electric current. This electric current will be changed in different expressions. The microcontroller device will process these flows. The phase logic is used for data processing that substantially increases its accuracy. The invented device does not use chemicals to detect caries which is quite safe and affordable. Comparison the result of diagnosis of damaged tooth using this device with diagnoses of two independent dentists indicated more accuracy, efficiency and confidential (p < 0.01). The invented device can be used as the primary method of dental caries

In vitro Osteogenic impulse effect of Dexamethasone on periodontal ligament stem cells

Periodontium is a complex organ composed of mineralized epithelial and connective tissue. Dexamethasone could stimulate proliferation of osteoblast and fibroblasts. This study aimed to assess the osteogenic effect of dexamethasone on periodental ligament (PDL) stem cells. PDL stem cells were collected from periodontal ligament tissue of root of extracted premolar of young and healthy people. The stem cells were cultured in alpha-MEM Medium in three groups, one group with basic medium contains (alpha-MEM and FBS 10 and 50 mmol of beta gelisrophosphat and L ascorbic acid mu g/ml), the second group: basic medium with dexamethasone and the third one: basic medium without any osteogenic stimulant. Mineralization of cellular layer was analyzed with Alizarin red stain method. Osteogenic analysis was done by Alkaline phosphates and calcium test. These analysis indicated that the amount of intra-cellular calcium and alkaline phosphates in the Dexamethasone group was far more than the control and basic group (P<0.05). The results of Alizarin red stain indicated more mineralization of cultured cells in Dexamethasone group (P<0.05). The study results showed that Dexamethasone has significant osteogenic effect on PDL stem cells and further studies are recommended to evaluate its effect on treatment of bone disorders

The prevalence of the localized aggressive periodontitis among students at 14-16 years in Ilam, Iran

The localized aggressive periodontitis, called an early onset periodontitis, is periodontal tissue destruction that symptoms appear at adolescence and youth that the prevalence of it is different in different areas. The crosssectional present study was done by two-step method on 1000 individuals at 14-16 years high school students. The examination was done in two parts. After isolating samples at office school in normal light, overthrow of the lips and cheeks by tongue blade or mirror examination, the pockets of mesiobuccal, mesiolingual, distobuccal, distolingual, buccal and lingual of first molar and incisors of both jaw were measured by Williams probe. In step two the suspicious student invited to clinic for more diagnosis. Other information was collected by Questionnaire. There were 500 boys and 500 girls that were examined. In the first step of examination, the 32 individuals who suspected were isolated. In the second examination, the 7 persons isolated as patient. The prevalence of that was 0.7 in population. ). The prevalence divided into 0.3 females and 0.4& males. By Chi-square was determined that there wasn't any significant relationship about gender (p>0.05). In respect of 0.7 prevalence for local aggressive periodontitis in Ilam, Iran and the prevalence around the world about 0.1-0.3, it can concluded that Ilam has the more prevalence and it needs more healthy services attention

The effect of 1.2mg simvastatin mouthwash on the level of interleukin-6 in patients with chronic periodontitis

Various materials and methods are nowadays used as complementary therapies for leveling the root surface for the treatment of periodontal diseases. The present study was conducted to evaluate the efficacy of simvastatin mouthwash on the level of interleukin-6 as an inflammatory cytokine that is supposed to be effective in the development of chronic periodontitis. The present randomized, double-blind clinical trial was conducted on 40 patients with moderate to severe chronic periodontitis. Initially, scaling and leveling the root surfaces were conducted for all patients and necessary training was presented; subjects in the intervention group, in addition to scaling, received 1.2simvastatin mouthwash. The level of interleukin-6 was measured before and one month after intervention, and data was analyzed by SPSS using paired t-test and covariance analysis. After treatment, there turned out to be a significant decrease in the level of interleukin-6 in the intervention group compared to the control group (P <0.05). The findings of the present study showed an increase in the clinical efficacy of treatment of chronic periodontitis with oral administration of 1.2 mg simvastatin as complementary therapy with scaling and leveling of the root surface. © 2019, Indian Journal of Forensic Medicine and Toxicology. All rights reserved

Study of the inhibitory effect of Quercus Coccifera's aqueous extract on Staphylococcus aureus and Pseudomonas aeruginosa In vitro

The use of therapeutic herbs has become of great importance these days due to the increase in drug resistance. From a long time ago the Venus' navel plant has been used to treat infections. In this study the antibacterial effect of the aqueous extract from the Quercus coccifera (jaft) herb, under laboratory conditions. This study was carried out experimentally. After collecting the Venus navel herb, it was dried in a warm dry environment away from direct sunlight in the shade. The alcoholic extract was prepared using a standard method. Clinical samples of staphylococcus aureus and pseudomonas aeruginosa were acquired from Ilam's health care institutes. The inhibitory effect of the extracts was analysed in the Mueller Hinton using the disk diffusion method for both bacteria. Then MIC and MBC of the extracts was determined using the Macro broth dilution method. At its highest concentration the aqueous extract had an inhibition zone of 27.2 and 23.7 mm on staphylococcus aureus and pseudomonas aeruginosa consecutively. The MIC and MBC for staphylococcus aureus were 10 and 12.5 microg/ml and for pseudomonas aeruginosa they were 10 and 17.5 microg/m consecutively. The results of this study show the strong antimicrobial effect of jaft's aqueous extract on staphylococcus aureus and pseudomonas aeruginosa and if more studies are based on this topic it could be a substitute for common antibiotics

Evaluation of Oral and Dental complications caused by Cyclophosphamide in patients with breast cancer in the Shahid-Mostafa Hospital, Ilam, 2019

Introduction: The use of chemotherapy over many years has attracted the attention of cancer patients for the treatment or prolongation of significant benefits, but unfortunately, in addition to all the advantages it has, there are consequences. Side effects of chemotherapy in the oral-pink area include inflammation, mouth ulcers, increased prevalence of viral, fungal, bacterial and bleeding infections. These side effects cause significant pain, malnutrition, and even, in some cases, a reduction in the amount of chemotherapy used by the treating physician. The aim of this study was to determine the oral and dental complications caused by cyclophosphamide in patients with breast cancer in the Department of Chemotherapy of Shahid Mostafa Hospital, Ilam Province in 2019. Materials and Method: The present study is an analytical-cross-sectional study performed on patients with breast cancer at Shahid Mostafa Hospital in Ilam in 2019-2020 and a researcher-made questionnaire was used to collect information. Results: The mean age of patients was 8.81±50.89 and their age range was between 36 and 69 years, and the mean body mass index was 2.56±24.18 and the range was between 29-19. All patients were female. 68.1 of dental patients, 20.3 had no dental caries, and 11.6 had no debar. The results showed that 89.9 of the patients had oral and dental complications with the use of silcophosphamide. 44.9 of pat ients had mild mucositis, none of them had moderate mucositis, and 55.1 had severe mucositis. Significant relationships were also found between dry mouth and the severity of mucositis. Patients with low-and moderate-grade dry mouth with severe mucositis were reported to be 31.3 and 75 percent, respectively. Conclusion: In the case of mucositis, the importance of oral hygiene in cancer patients should be emphasized. Although there is no scientific evidence that oral hygiene plays a role in the prevention and treatment of mucositis, most researchers believe that oral hygiene can reduce the duration and severity of mucositis. © RJPT All right reserved