Inflight and ground-based simulation of handling qualities of very large airplanes in landing approach

Inflight and ground based simulation of Boeing 367-80 variable stability aircraft handling qualities during landing approac

Identification of urban watershed units using remote multispectral sensing

Submitted to Office of Water Resources Research, U.S. Department of the Interior.Contains four aerial color photographs, secured to pages by means of glue.Includes bibliographical references.Completion report, OWRR project no. A-012-COLO

Bioethics and the Brain

Microelectronics and medical imaging are bringing us closer to a world where mind reading is possible and blindness banished - but we may not want to live there. New ways of imaging the human brain and new developments in microelectronics are providing unprecedented capabilities for monitoring the brain in real time and even for controlling brain function. The technologies are novel, but some of the questions that they will raise are not. Electrical activity in the brain can reveal the contents of a person\u27s memory. New imaging techniques might allow physician to detect devastating diseases long before those diseases become clinically apparent. And researchers may one day find brain activity that correlates with behavior patterns such as tendencies toward alcoholism, aggression, pedophilia, or racism. But how reliable will the information be, how should it be used, and what will it do to our notion of privacy? Meanwhile, microelectronics is making access to the brain a two-way street. The same electrical stimulation technologies that allow some deaf people to hear could be fashioned to control behavior as well. What are the appropriate limits to the use of this technology? Ethicists are only now beginning to take note of these developments in neuroscience

Infrared Behaviour of Systems With Goldstone Bosons

We develop various complementary concepts and techniques for handling quantum fluctuations of Goldstone bosons.We emphasise that one of the consequences of the masslessness of Goldstone bosons is that the longitudinal fluctuations also have a diverging susceptibility characterised by an anomalous dimension $(d-2)$ in space-time dimensions $2<d<4$.In $d=4$ these fluctuations diverge logarithmically in the infrared region.We show the generality of this phenomenon by providing three arguments based on i). Renormalization group flows, ii). Ward identities, and iii). Schwinger-Dyson equations.We obtain an explicit form for the generating functional of one-particle irreducible vertices of the O(N) (non)--linear $\sigma$--models in the leading 1/N approximation.We show that this incorporates all infrared behaviour correctly both in linear and non-linear $\sigma$-- models. Our techniques provide an alternative to chiral perturbation theory.Some consequences are discussed briefly.Comment: 28 pages,2 Figs, a new section on some universal features of multipion processes has been adde

Teachers as writers: a systematic review

This paper is a critical literature review of empirical work from 1990-2015 on teachers as writers. It interrogates the evidence on teachers’ attitudes to writing, their sense of themselves as writers and the potential impact of teacher writing on pedagogy or student outcomes in writing. The methodology was carried out in four stages. Firstly, educational databases keyword searches located 438 papers. Secondly, initial screening identified 159 for further scrutiny, 43 of which were found to specifically address teachers’ writing identities and practices. Thirdly, these sources were screened further using inclusion/exclusion criteria. Fourthly, the 22 papers judged to satisfy the criteria were subject to in-depth analysis and synthesis. The findings reveal that the evidence base in relation to teachers as writers is not strong, particularly with regard to the impact of teachers’ writing on student outcomes. The review indicates that teachers have narrow conceptions of what counts as writing and being a writer and that multiple tensions exist, relating to low self-confidence, negative writing histories, and the challenge of composing and enacting teacher and writer positions in school. However, initial training and professional development programmes do appear to afford opportunities for reformulation of attitudes and sense of self as writer

Systematic 1/N1/N corrections for bosonic and fermionic vector models without auxiliary fields

In this paper, colorless bilocal fields are employed to study the large $N$ limit of both fermionic and bosonic vector models. The Jacobian associated with the change of variables from the original fields to the bilocals is computed exactly, thereby providing an exact effective action. This effective action is shown to reproduce the familiar perturbative expansion for the two and four point functions. In particular, in the case of fermionic vector models, the effective action correctly accounts for the Fermi statistics. The theory is also studied non-perturbatively. The stationary points of the effective action are shown to provide the usual large $N$ gap equations. The homogeneous equation associated with the quadratic (in the bilocals) action is simply the two particle Bethe Salpeter equation. Finally, the leading correction in $1\over N$ is shown to be in agreement with the exact $S$ matrix of the model.Comment: 24 pages, uses REVTEX macros. Replaced with final version to appear in Phys. Rev.

Identification of RPS14 as a 5q- syndrome gene by RNA interference screen

Somatic chromosomal deletions in cancer are thought to indicate the location of tumor suppressor genes, whereby complete loss of gene function occurs through biallelic deletion, point mutation, or epigenetic silencing, thus fulfilling Knudson's two-hit hypothesis.1 In many recurrent deletions, however, such biallelic inactivation has not been found. One prominent example is the 5q- syndrome, a subtype of myelodysplastic syndrome (MDS) characterized by a defect in erythroid differentiation.2 Here, we describe an RNA interference (RNAi)-based approach to discovery of the 5q- disease gene. We find that partial loss of function of the ribosomal protein RPS14 phenocopies the disease in normal hematopoietic progenitor cells, and moreover that forced expression of RPS14 rescues the disease phenotype in patient-derived bone marrow cells. In addition, we identified a block in the processing of pre-rRNA in RPS14 deficient cells that is highly analogous to the functional defect in Diamond Blackfan Anemia, linking the molecular pathophysiology of the 5q- syndrome to a congenital bone marrow failure syndrome. These results indicate that the 5q- syndrome is caused by a defect in ribosomal protein function, and suggests that RNAi screening is an effective strategy for identifying causal haploinsufficiency disease genes

The next to leading order effective potential in the 2+1 dimensional Nambu-Jona-Lasinio model at finite temperature

The finite temperature effective potential in the 2+1 dimensional Nambu-Jona-Lasinio model is constructed up to the next to leading order in the large $N$ expansion, where $N$ is the number of flavors in the model. The distinctive feature of the analysis is an inclusion of an additional scalar field, which allows us to circumvent the well known, and otherwise unavoidable problem with the imaginary contribution to the effective potential. In accordance with the Mermin-Wagner-Coleman theorem, applied to the dimensionally reduced subsystem of the zero Matsubara modes of the composite boson fields, the finite temperature effective potential reveals a global minimum at the zero of the composite order parameter. This allows us to conclude that the continuous global symmetry of the NJL model is not broken for any arbitrarily small, finite temperature.Comment: 12 pages, 4 figures, REVTe