No-Dictionary Scrabble Revisited

In the November 1974 Word Ways, Ralph Beaman constructed a Scrabble game scoring 5609 points, assuming that any combination of letters formed a word. Using the diagram below, Stephen Root devised a game scoring 5874 points. By rearranging Stephen Root\u27s moves, Charles F. Brown of Albuquerque raised the score two more points, to 5876

Internal visual workmanship standard for microelectronic devices /NASA STD XX-2/ and training manual, volume 2

Internal visual workmanship standards for monolithic microelectronic devices - training manua

Best Scrabble Game, Best Clabbers Game

In past Word Ways issues, Ron Jerome, Ralph Beaman and Jeff Grant presented high-scoring Scrabble games of 4047, 4142, and 4454 points, respectively. All were based on the word BENZOXYCAMPHORS, a word not sanctioned by the National Scrabble Association. The game below, scoring 3986 points, uses only words from the OSPD or Webster\u27s Tenth Collegiate

The C@merata Task at MediaEval 2015: Natural Language Queries on Classical Music Scores

This was the second year of the C@merata task [16,1] which relates natural language processing to music inform ation retrieval. Participants each build a system which takes as input a query and a music score and produces as output one or more ma tching passages in the score. This year, questions were mo re difficult and scores were more complex. Participants were the same as last year and once again CLAS was the best with a Beat F-Score of 0.620

The C@merata Task at MediaEval 2014: Natural Language Queries on Classical Music Scores

This paper summarises the C@merata task in which participants built systems to answer short natural language queries about classical music scores in MusicXML. The task thus combined natural language processing with music information retrieval. Five groups from four countries submitted eight runs. The best submission scored Beat Precision 0.713 and Beat Recall 0.904

Clergy Interest in Innovative Collaboration with Psychologists

What forms of innovative collaboration are possible between clergy and psychologists? A total of 117 clergypersons (63% response rate) rated 6 scenarios of collaboration, indicating their level of interest and the extent to which they would like to remain involved with the psychologist. The scenarios were derived from two categories of collaboration articulated by in previous research: mental health services and enhancing parish life. Overall, clergy expressed relatively modest levels of interest in innovative collaboration, though they were somewhat interested in mental health consultation services. Many clergy refer troubled parishioners to clinical or counseling psychologists for treatment, but appear less interested in more innovative forms of collaboration

Multi-scale Renormalisation Group Improvement of the Effective Potential

Using the renormalisation group and a conjecture concerning the perturbation series for the effective potential, the leading logarithms in the effective potential are exactly summed for $O(N)$ scalar and Yukawa theories.Comment: 19 pages, DIAS STP 94-09. Expanded to check large N limit, typo's corrected, to appear in Phys Rev

Dallas with balls: televized sport, soap opera and male and female pleasures

Two of the most popular of television genres, soap opera and sports coverage have been very much differentiated along gender lines in terms of their audiences. Soap opera has been regarded very much as a 'gynocentric' genre with a large female viewing audience while the audiences for television sport have been predominantly male. Gender differentiation between the genres has had implications for the popular image of each. Soap opera has been perceived as inferior; as mere fantasy and escapism for women while television sports has been perceived as a legitimate, even edifying experience for men. In this article the authors challenge the view that soap opera and television sport are radically different and argue that they are, in fact, very similar in a number of significant ways. They suggest that both genres invoke similar structures of feeling and sensibility in their respective audiences and that television sport is a 'male soap opera'. They consider the ways in which the viewing context of each genre is related to domestic life and leisure, the ways in which the textual structure and conventions of each genre invoke emotional identification, and finally, the ways in which both genres re-affirm gender identities

Potent and Broad Inhibition of HIV-1 by a Peptide from the gp41 Heptad Repeat-2 Domain Conjugated to the CXCR4 Amino Terminus.

HIV-1 entry can be inhibited by soluble peptides from the gp41 heptad repeat-2 (HR2) domain that interfere with formation of the 6-helix bundle during fusion. Inhibition has also been seen when these peptides are conjugated to anchoring molecules and over-expressed on the cell surface. We hypothesized that potent anti-HIV activity could be achieved if a 34 amino acid peptide from HR2 (C34) were brought to the site of virus-cell interactions by conjugation to the amino termini of HIV-1 coreceptors CCR5 or CXCR4. C34-conjugated coreceptors were expressed on the surface of T cell lines and primary CD4 T cells, retained the ability to mediate chemotaxis in response to cognate chemokines, and were highly resistant to HIV-1 utilization for entry. Notably, C34-conjugated CCR5 and CXCR4 each exhibited potent and broad inhibition of HIV-1 isolates from diverse clades irrespective of tropism (i.e., each could inhibit R5, X4 and dual-tropic isolates). This inhibition was highly specific and dependent on positioning of the peptide, as HIV-1 infection was poorly inhibited when C34 was conjugated to the amino terminus of CD4. C34-conjugated coreceptors could also inhibit HIV-1 isolates that were resistant to the soluble HR2 peptide inhibitor, enfuvirtide. When introduced into primary cells, CD4 T cells expressing C34-conjugated coreceptors exhibited physiologic responses to T cell activation while inhibiting diverse HIV-1 isolates, and cells containing C34-conjugated CXCR4 expanded during HIV-1 infection in vitro and in a humanized mouse model. Notably, the C34-conjugated peptide exerted greater HIV-1 inhibition when conjugated to CXCR4 than to CCR5. Thus, antiviral effects of HR2 peptides can be specifically directed to the site of viral entry where they provide potent and broad inhibition of HIV-1. This approach to engineer HIV-1 resistance in functional CD4 T cells may provide a novel cell-based therapeutic for controlling HIV infection in humans