Rescue intracranial stenting for acute ischemic stroke after the failure of mechanical thrombectomy: A systematic review, meta-analysis, and trial sequential analysis

BackgroundIntracranial rescue stenting (RS) might be an option for acute ischemic stroke after the failure of mechanical thrombectomy (MT). However, the findings were not consistent in previous systematic reviews, and whether the conclusion was supported by sufficient statistical power is unknown.AimTo examine the effect of RS on acute ischemic stroke after the failure of MT with a systematic review, meta-analysis, and trial sequential analysis (TSA).MethodsWe searched Ovid Medline, Embase, and the Cochrane Central Register of Controlled Trials (CENTRAL) from inception to 15 June 2022, without any language restriction. Studies assessing the effect of RS for acute ischemia stroke after MT failure were included. Two reviewers independently screened the retrieved articles, extracted data, and evaluated the quality of the included studies through the New Ottawa Scale (NOS). The primary outcome was the recanalization rate after RS. Secondary outcomes included modified Rankin Scale (mRS) at 3 months after stroke, symptomatic intracranial hemorrhage (sICH), and mortality rate. We synthesized the data through a random-effects model and performed a TSA analysis.ResultsWe included 15 studies (containing 1,595 participants) after screening 3,934 records. The pooled recanalization rate for rescue stenting was 82% (95% CI 77–87%). Compared with non-stenting, rescue stenting was associated with a higher proportion of patients with 0–2 mRS score (OR 3.96, 95% CI 2.69–5.84, p < 0.001) and a lower 90-day mortality rate (OR 0.46, 95% CI 0.32–0.65, p < 0.001), and stenting did not increase sICH rate (OR 0.63, 95% CI 0.39–1.04, p = 0.075). The TSA analysis showed that the meta-analysis of the mRS score had a sufficient sample size and statistical power.ConclusionsOur study showed that rescue stenting was effective and safe for patients with acute ischemia stroke who also had a failed MT, and this result was confirmed in a TSA analysis

A Method for Designing the Architecture of Intelligent Transportation Systems in the People's Republic of China

Relevance of the research topic. With the rapid development of the social economy and technology, the number of existing cars and drivers has increased rapidly, and the construction of the urban road information management system has been relatively lagging behind, leading to the incompatibility of the existing traffic management model with the rapidly growing demand for transportation. Intelligent transportation systems (ITS) have been developed very complete and mature in many developed countries in the world and are widely used. With the development of technology, intelligent transportation systems will be increasingly used in urban traffic. The development of intelligent transport will be a promising direction for the development of transport in cities of the second and third echelon

Design, fabrication and characteristic of two-layer microwave absorbers composed of magnetic micropowder-rubber composites in X-band frequency range

Both experimentally and theoretically, a two-layer microwave absorber exhibits the possibility of meeting the demand for effective radar absorbing materials. The design methodology is based on the modulus of permittivity (permeability) which obeys a logarithmic law of mixtures, and the loss tangent is related through a linear law of mixtures. A linear regression analysis performed on the data points provides constants that can be used to predict the effective parameters at different frequencies, and a program is presented that computes the optimum amount of magnetic micropowder and the required thickness for each layer. A two-step sulfur treatment is then applied to preparation of the two-layer absorber, vulcanized firstly by heating at 165\,^{\circ }{\rm C} for 15 min and then at 150\,^{\circ }{\rm C} for 4 h. Finally, tensile strength is experimentally investigated as well as power reflection coefficient. Test results indicate the two-layer absorber has excellent mechanical and microwave attenuation properties for X-band frequency

Influence of the electromagnetic parameters on the surface wave attenuation in thin absorbing layers

This paper describes the relationships between the surface wave attenuation properties and the electromagnetic parameters of radar absorbing materials (RAMs). In order to conveniently obtain the attenuation constant of TM surface waves over a wide frequency range, the simplified dispersion equations in thin absorbing materials were firstly deduced. The validity of the proposed method was proved by comparing with the classical dispersion equations. Subsequently, the attenuation constants were calculated separately for the absorbing layers with hypothetical relative permittivity and permeability. It is found that the surface wave attenuation properties can be strongly tuned by the permeability of RAM. Meanwhile, the permittivity should be appropriate so as to maintain high cutoff frequency. The present work provides specific methods and designs to improve the attenuation performances of radar absorbing materials

Metal-Based Graphical SiO2/Ag/ZnS/Ag Hetero-Structure for Visible-Infrared Compatible Camouflage

A brand-new approach to realizing visible-infrared compatible camouflage is proposed based on a metal-based graphical hetero-structure (MGHS) SiO2/Ag/ZnS/Ag. For different thicknesses (20, 40, and 60 nm) of color-controlling sub-layer, high-contract and large-span structure colors (yellow, navy, and cyan) were observed due to reintroducing constructive interference with a matching intensity of reflected waves. Ultra-low infrared emissivity values of 0.04, 0.05, and 0.04 (with high average reflectance values of 95.46%, 95.31%, and 95.09%) were obtained at 3–14 μm. In addition, the well-performing trisecting-circle structure further indicates that it is feasible to design on-demand compatible camouflage patterns using the easily-prepared MGHS

Effects of Nonelastic Taping and Dual Task on Kinematics and Kinetics of the Ankle Joint

Objectives. The purpose of this experimental study was to investigate the effects of nonelastic taping and dual task on ankle kinematics and kinetics in gait analysis of healthy adults. Methods. A total of 21 healthy adults completed trials of gait analysis using a Vicon system combining ground walking with different cognitive task conditions (none, modified Stroop color/character naming, and serial-7 subtraction), with or without nonelastic taping. Ankle kinematics and kinetics including speed, ankle plantarflexion and inversion angle, ground reaction force (GRF), and stride time variability (STV) under all conditions of taping (YES or NO) and cognitive task (none, naming, and subtraction) were characterized and analyzed with repeated-measures ANOVA. Results. As regards cognitive performance, the serial-7 subtraction performance under walking conditions with and without taping was significantly poorer than simple sitting condition (P<0.001). For kinematics and kinetics, STV showed statistically significant decrease (P=0.02) when subjects underwent taping application. Vertical GRF was significantly greater under taping than barefoot (P=0.001). Ankle plantarflexion at initial contact (IC) under the dual-task walking was significantly more than under simple walking (P=0.008). Conclusions. Applications of nonelastic taping and dual task may lead to the STV, vertical GRF, ankle plantarflexion, and speed alterations because of restricted joint range of motion and changed sensorimotor neural circuit. When healthy adults performed dual-task walking, central neural resources allocation was disturbed, leading to weakened performance in both motor and cognitive tasks

Preparation and microwave absorption properties of honeycomb core structures coated with composite absorber

Honeycomb structure coated with paraffin filled with composite of graphene and flaky carbonyl iron powder (FCIP) as lossy filler have been studied. The composite of graphene/FCIP with different weight ratio were synthesized via mechanical milling, the electromagnetic properties of the samples were measured by transmission/reflection method in the frequency range of 8-12 GHz. The microwave absorbing properties of the microwave absorbing honeycomb structure (MAHS) and microwave absorbing honeycomb sandwich structure (MAHSS) were studied based on the Finite Element Method with periodical boundary conditions. The matching layer on the top of the honeycomb sandwich structure can enhanced the microwave absorption properties. It was shown that a light weight and broadband MAHSS could be implemented with the use of the magnetic material and dielectric material

Synthesis of <i>a</i>‑Alkylated Ketones via Tandem Acceptorless Dehydrogenation/<i>a</i>‑Alkylation from Secondary and Primary Alcohols Catalyzed by Metal–Ligand Bifunctional Iridium Complex [Cp*Ir(2,2′-bpyO)(H₂O)]

A new strategy for the synthesis of α-alkylated ketones via tandem acceptorless dehydrogenation/α-alkylation from secondary and primary alcohols was proposed and accomplished. In the presence of metal–ligand bifunctional iridium complex [Cp*Ir­(2,2′-bpyO)­(H₂O)], various desirable products were obtained in high yields. Compared with previous methods for the direct dehydrogenative coupling of secondary alcohols with primary alcohols to α-alkylated ketones, this protocol has obvious advantages including complete selectivity for α-alkylated ketones and more environmentally benign conditions. Notably, the study also exhibited the potential to develop tandem reactions catalyzed using a metal–ligand bifunctional iridium complex