NIPT T21 Modeled Performance at Low Fetal Fractions.

<p>In figure, 27,824 samples that passed all laboratory quality criteria with fetal fractions between 4 and 8% were fitted into two normal distributions, one for euploids and one for T21 positives. The fitted distribution was used to estimate specificity and sensitivity.</p

Breakdown of the NIPT Final Results.

<p>Trisomy 13 and 18 began reporting in February 2012.</p><p>Breakdown of the NIPT Final Results.</p

Average NIPT Patient Demographics (n = 100,000).

<p>Gestational age was determined by LMP or ultrasound. Maternal height and weight are not required for testing and not provided for all samples, n = 86,734.</p><p>Average NIPT Patient Demographics (n = 100,000).</p

NIPT Laboratory Performance.

<p>The table shows key laboratory performance indicators. Business days are defined as Monday through Friday excluding federal holidays. Canceled tests are samples that are inappropriate for testing primarily those with no indication for testing. Amended reports primarily include reports amended for typographical errors.</p><p>NIPT Laboratory Performance.</p

Impact of BMI on Final Results.

<p>This figure shows a breakdown of final results when binned by maternal BMI. The number of patients in each bin is displayed above their respective bin.</p