167 research outputs found

    Shopping Mall Patronage: A Review of Predictive Factors

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    Given the increasing popularity of shopping malls globally, it is vital for would-be investors and their consultants (bankers, estate surveyors and valuers, among others) to examine the critical variables for the feasibility and viability of such an investment. Taking this into consideration, a systematic review of prior studies on shopping malls was conducted with the aim of highlighting the factors predicting patronage. To accomplish this aim, the researchers reviewed papers published within a ten-year period. According to the summary, research on shopping malls has gotten a lot of attention, especially in developing countries. The study also discovered that, in both developed and developing countries, income, location, accessibility, and price are the most important factors influencing mall patronage. In conclusion, shopping mall stakeholders should consider using the fifteen variables highlighted in this study as an investment guide

    Benefits and Barriers to the Implementation of Green Building Standards in Universities: What are Students’ Views?

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    Embracing the principles of green building in development is crucial in creating a sustainable environment. However, research on its adoption in educational institutions is very low and students’ opinions are not given priority in the few research that are available in Nigeria. This study therefore investigated the perception of built environment students on the need to embrace the principles of green building in Covenant University, Ota, Ogun State, Nigeria. 101 questionnaires were administered to students in the Departments of Architecture, Building Technology and Estate Management of the university and a response rate of 94% was achieved. The data collected was analysed using descriptive statistics such as percentage, weighted mean and relative importance index (RII) and the data was presented in tables. The study revealed that 88.42% of the students are aware of the concept of green building. According to the students, the degree of embracing green building standards in Covenant University is very low. Moreover, the benefits the students perceive the university can derive from adopting green building principles are: improved indoor air and water quality, reduction in pollution and environmental degradation, energy efficiency and water conservation. In addition, the students identified the following as the main barriers to green building adoption: ignorance on green building principles and their benefits (RII =0.91), high cost of green building technology (RII = 0.89), ignorance on professional knowledge and expertise on green building (RII = 0.89), ignorance on green building principles promotion by government (RII = 0.87) and ignorance on importance attached to green building principles by management of universities (RII = 0.87). The study recommended, amongst others, that there should be a forum where university management teams can be enlightened on the gains of embracing green building standards. This study is expected to broaden the knowledge of the Management of Covenant University on the importance of green development which will make the university environment to be conducive for learning, which will in turn aid better students’ academic performance. The study concluded that green building principles are vital to the physical and aesthetic planning of any development as it will reduce the amount of raw materials used in construction

    BIG DATA AND REAL ESTATE: A REVIEW OF LITERATURE

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    The concept of big data though relatively new has brought a lot of solutions to modern day challenges. Many authors, particularly in developed countries, have adopted the concept in tackling the numerous challenges unfolding in the real estate profession. However, most of the findings from these authors are on individual bases and as such, there is a need to reach a general consensus on the relevance of big data to the real estate profession. The review shows the impact of big data to include digitization of records, information on user preferences, sensor information on the urban environment and sensor information on movement. The paper concludes that the relevance of big data to the real estate profession cannot be over-emphasised

    Can screening and brief intervention lead to population-level reductions in alcohol-related harm?

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    A distinction is made between the clinical and public health justifications for screening and brief intervention (SBI) against hazardous and harmful alcohol consumption. Early claims for a public health benefit of SBI derived from research on general medical practitioners' (GPs') advice on smoking cessation, but these claims have not been realized, mainly because GPs have not incorporated SBI into their routine practice. A recent modeling exercise estimated that, if all GPs in England screened every patient at their next consultation, 96% of the general population would be screened over 10 years, with 70-79% of excessive drinkers receiving brief interventions (BI); assuming a 10% success rate, this would probably amount to a population-level effect of SBI. Thus, a public health benefit for SBI presupposes widespread screening; but recent government policy in England favors targeted versus universal screening, and in Scotland screening is based on new registrations and clinical presentation. A recent proposal for a national screening program was rejected by the UK National Health Service's National Screening Committee because 1) there was no good evidence that SBI led to reductions in mortality or morbidity, and 2) a safe, simple, precise, and validated screening test was not available. Even in countries like Sweden and Finland, where expensive national programs to disseminate SBI have been implemented, only a minority of the population has been asked about drinking during health-care visits, and a minority of excessive drinkers has been advised to cut down. Although there has been research on the relationship between treatment for alcohol problems and population-level effects, there has been no such research for SBI, nor have there been experimental investigations of its relationship with population-level measures of alcohol-related harm. These are strongly recommended. In this article, conditions that would allow a population-level effect of SBI to occur are reviewed, including their political acceptability. It is tentatively concluded that widespread dissemination of SBI, without the implementation of alcohol control measures, might have indirect influences on levels of consumption and harm but would be unlikely on its own to result in public health benefits. However, if and when alcohol control measures were introduced, SBI would still have an important role in the battle against alcohol-related harm

    Type III Nrg1 Back Signaling Enhances Functional TRPV1 along Sensory Axons Contributing to Basal and Inflammatory Thermal Pain Sensation

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    Type III Nrg1, a member of the Nrg1 family of signaling proteins, is expressed in sensory neurons, where it can signal in a bi-directional manner via interactions with the ErbB family of receptor tyrosine kinases (ErbB RTKs) [1]. Type III Nrg1 signaling as a receptor (Type III Nrg1 back signaling) can acutely activate phosphatidylinositol-3-kinase (PtdIns3K) signaling, as well as regulate levels of α7* nicotinic acetylcholine receptors, along sensory axons [2]. Transient receptor potential vanilloid 1 (TRPV1) is a cation-permeable ion channel found in primary sensory neurons that is necessary for the detection of thermal pain and for the development of thermal hypersensitivity to pain under inflammatory conditions [3]. Cell surface expression of TRPV1 can be enhanced by activation of PtdIns3K [4], [5], [6], making it a potential target for regulation by Type III Nrg1. We now show that Type III Nrg1 signaling in sensory neurons affects functional axonal TRPV1 in a PtdIns3K-dependent manner. Furthermore, mice heterozygous for Type III Nrg1 have specific deficits in their ability to respond to noxious thermal stimuli and to develop capsaicin-induced thermal hypersensitivity to pain. Cumulatively, these results implicate Type III Nrg1 as a novel regulator of TRPV1 and a molecular mediator of nociceptive function

    The PROVENT-C19 registry: A study protocol for international multicenter SIAARTI registry on the use of prone positioning in mechanically ventilated patients with COVID-19 ARDS

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    Background The worldwide use of prone position (PP) for invasively ventilated patients with COVID-19 is progressively increasing from the first pandemic wave in everyday clinical practice. Among the suggested treatments for the management of ARDS patients, PP was recommended in the Surviving Sepsis Campaign COVID-19 guidelines as an adjuvant therapy for improving ventilation. In patients with severe classical ARDS, some authors reported that early application of prolonged PP sessions significantly decreases 28-day and 90-day mortality. Methods and analysis Since January 2021, the COVID19 Veneto ICU Network research group has developed and implemented nationally and internationally the "PROVENT-C19 Registry", endorsed by the Italian Society of Anesthesia Analgesia Resuscitation and Intensive Care. . .'(SIAARTI). The PROVENT-C19 Registry wishes to describe 1. The real clinical practice on the use of PP in COVID-19 patients during the pandemic at a National and International level; and 2. Potential baseline and clinical characteristics that identify subpopulations of invasively ventilated patients with COVID-19 that may improve daily from PP therapy. This web-based registry will provide relevant information on how the database research tools may improve our daily clinical practice. Conclusions This multicenter, prospective registry is the first to identify and characterize the role of PP on clinical outcome in COVID-19 patients. In recent years, data emerging from large registries have been increasingly used to provide real-world evidence on the effectiveness, quality, and safety of a clinical intervention. Indeed observation-based registries could be effective tools aimed at identifying specific clusters of patients within a large study population with widely heterogeneous clinical characteristics. Copyright

    Dysglycemias in pregnancy: from diagnosis to treatment. Brazilian consensus statement

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    There is an urgent need to find consensus on screening, diagnosing and treating all degrees of DYSGLYCEMIA that may occur during pregnancies in Brazil, considering that many cases of DYSGLYCEMIA in pregnant women are currently not diagnosed, leading to maternal and fetal complications. For this reason the Brazilian Diabetes Society (SBD) and the Brazilian Federation of Gynecology and Obstetrics Societies (FEBRASGO), got together to introduce this proposal. We present here a joint consensus regarding the standardization of clinical management for pregnant women with any degree of Dysglycemia, on the basis of current information, to improve medical assistance and to avoid related complications of Dysglycemia in pregnancy to the mother and the fetus. This consensus aims to standardize the diagnosis among general practitioners, endocrinologists and obstetricians allowing the dissemination of information in basic health units, public and private services, that are responsible for screening, diagnosing and treating disglycemic pregnant patients

    Breastfeeding and weaning practices among Hong Kong mothers: a prospective study

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    <p>Abstract</p> <p>Background</p> <p>Breastfeeding provides optimal and complete nutrition for newborn babies. Although new mothers in Hong Kong are increasingly choosing to breastfeed their babies, rates of exclusive breastfeeding are low and duration remains short. The purpose of this study was to describe the breastfeeding and weaning practices of Hong Kong mothers over the infant's first year of life to determine the factors associated with early cessation.</p> <p>Methods</p> <p>A cohort of 1417 mother-infant pairs was recruited from the obstetric units of four public hospitals in Hong Kong in the immediate post-partum period and followed prospectively for 12 months or until weaned. We used descriptive statistics to describe breastfeeding and weaning practices and multiple logistic regression to investigate the relationship between maternal characteristics and breastfeeding cessation.</p> <p>Results</p> <p>At 1 month, 3 months, 6 months and 12 months only 63%, 37.3%, 26.9%, and 12.5% of the infants respectively, were still receiving any breast milk; approximately one-half of breastfeeding mothers were exclusively breastfeeding. Younger mothers, those with a longer duration of residence in Hong Kong, and those returning to work postpartum were more likely to wean before 1 month. Mothers with higher education, previous breastfeeding experience, who were breastfed themselves and those who were planning to exclusively breastfeed and whose husbands preferred breastfeeding were more likely to continue breastfeeding beyond 1 month. The introduction of infant formula before 1 month and returning to work postpartum were predictive of weaning before 3 months.</p> <p>Conclusions</p> <p>Breastfeeding promotion programs have been successful in achieving high rates of breastfeeding initiation but the focus must now shift to helping new mothers exclusively breastfeed and sustain breastfeeding for longer.</p
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