13 research outputs found
Divulgación de la química en los diversos niveles educativos
Póster presentado en: VIII Jornadas de Innovación Docente de la UBU, Burgos, 5 de abril de 2016, organizadas por el Instituto de Formación e Innovación Educativa-IFIE de la Universidad de Burgo
Complementary regioselectivity in the synthesis of iminohydantoins: remarkable effect of amide substitution on the cyclization
Complementary regioselective synthesis of iminohydantoins from isocyanoacetamides controlled by the substituent on the amide group has been described. 4-Iminohydantoins were the major products when the starting materials were N-alkyl isocyanoamides, whereas 2-iminohydantoins were the major products with N-aryl isocyanoamides.Ministerio
de Ciencia e Innovación, Spain (Project CTQ2009-12631-
BQU), Junta de Castilla y León, Consejería de Educación y
Cultura y Fondo Social Europeo (Projects BU023A09 and
GR170)
Synthesis of Pyrrolidine-Fused 1,3-Dithiolane Oligomers by the Cycloaddition of Polycyclic Dithiolethiones to Maleimides and Evaluation as Mercury(II) Indicators
The scandium triflate-catalyzed cycloaddition reaction
of polycyclic 1,2-dithiolethiones to maleimides is described. The
reaction constitutes an easy approach to linear as well as branched
oligomeric cis-fused dihydro[1,3]dithiolo[4,5-c]pyrrole-4,6-dione
rings interconnected by 3,5-diylidenethiomorpholine-2,6-dithione or
ylidene-6-thioxo[1,2]dithiolo[3,4-b][1,4]thiazin-3-one groups. The
presence of highly colored, highly polarized push−pull α,β-
unsaturated thione groups in their structures make these compounds
sensitive to the presence of mercury(II) cation in organic or mixed
organic/aqueous solvents.Ministerio
de Economía
y Competitividad, Spain (Project CTQ2012-
31611), Junta de Castilla y León, Consejería
de Educación y
Cultura y Fondo Social Europeo (Project BU246A12-1), and the
European Commission Seventh Framework Programme (Project
SNIFFER FP7-SEC-2012-312411)
Synthesis of Catechol Derived Rosamine Dyes and Their Reactivity toward Biogenic Amines
Functional organic dyes play a key role in many fields, namely in biotechnology and medical diagnosis. Herein, we report two novel 2,3- and 3,4-dihydroxyphenyl substituted rosamines (3 and 4, respectively) that were successfully synthesized through a microwave-assisted protocol. The best reaction yields were obtained for rosamine 4, which also showed the most interesting photophysical properties, specially toward biogenic amines (BAs). Several amines including n- and t-butylamine, cadaverine, and putrescine cause spectral changes of 4, in UV–Vis and fluorescence spectra, which are indicative of their potential application as an effective tool to detect amines in acetonitrile solutions. In the gas phase, the probe response is more expressive for spermine and putrescine. Additionally, we found that methanolic solutions of rosamine 4 and n-butylamine undergo a pink to yellow color change over time, which has been attributed to the formation of a new compound. The latter was isolated and identified as 5 (9−aminopyronin), whose solutions exhibit a remarkable increase in fluorescence intensity together with a shift toward more energetic wavelengths. Other 9-aminopyronins 6a, 6b, 7a, and 7b were obtained from methanolic solutions of 4 with putrescine and cadaverine, demonstrating the potential of this new xanthene entity to react with primary amines.Financial support from PT national funds (FCT/MCTES, Fundação para a Ciência e a Tecnologia and Ministério da Ciência, Tecnologia e Ensino Superior) through the project PTDC/QUI-QOR/29426/2017. The research team would like to thank the projects UIDB/50006/2020, PTDC/QUI-QIN/28142/2017 and Grant BU263P18 (from the Junta de Castilla y León, Consejería de Educación y Cultura y Fondo Social Europeo). F. M. -S. gratefully acknowledges FCT (Portugal’s Foundation for Science and Technology) within grant DFA/BD/9136/2020. A.M.G.S. and A.L. thank FCT for the program DL 57/2016 – Norma transitória
Synthesis of Fluorogenic Arylureas and Amides and Their Interaction with Amines: A Competition between Turn-on Fluorescence and Organic Radicals on the Way to a Smart Label for Fish Freshness
We describe the synthesis of fluorogenic arylureas and amides and their interaction with primary or secondary amines under air and light in organic-aqueous mixtures to give rise to a new class of persistent organic radicals, described on the basis of their electron paramagnetic resonance (EPR), as well as UV–vis, fluorescence, NMR, and quantum mechanics calculations, and their prospective use as multi-signal reporters in a smart label for fish freshness.Funded by the NATO Science for Peace and Security Programme (Grant SPS G5536), the Junta de Castilla y León, Consejería de Educación y Cultura y Fondo Social Europeo (Grant BU263P18), and the Ministerio de Ciencia e Innovación (Grant PID2019-111215RB-100
Sostenibilidad curricular de titulaciones universitarias: un proyecto del Grupo SAC-UBU para conocer la percepción del alumnado de la Facultad de Ciencias
Póster presentado en: VIII Jornadas de Innovación Docente de la UBU, Burgos, 5 de abril de 2016, organizadas por el Instituto de Formación e Innovación Educativa-IFIE de la Universidad de Burgo
Trabajo en grupo en la asignatura Química Orgánica del Grado de CYTA
Póster presentado en: VIII Jornadas de Innovación Docente de la UBU, Burgos, 5 de abril de 2016, organizadas por el Instituto de Formación e Innovación Educativa-IFIE de la Universidad de Burgo