8 research outputs found
Average CTV coverages and homogeneities per modality of all included plans.
<p>Average CTV coverages and homogeneities per modality of all included plans.</p
Robustness performance of PTV and minimax optimization.
<p>Nominal D<sub>98</sub> (blue) and worst-case scenario (red) of PTV-based (a,c) and minimax IMPT plans (b,d) for CTV<sub>70</sub> (a-b) and CTV<sub>54.25</sub> (c-d). Solid lines connect the averages and boxplots represent the distribution of these parameters of all patients per plan type. The horizontal blue lines represent the CTV dose criterion that marks 95% of the prescribed dose (66.5 Gy and 51.5 Gy).</p
Field configurations used for IMPT and IMRT plans.
<p>Field configurations used for IMPT and IMRT plans.</p
NTCP benefit of IMPT with different field configurations compared to IMRT.
<p>∆NTCP and 95% confidence interval are given as a function of number of minimax-optimized IMPT fields for xerostomia (left), dysphagia (right), for all patients (upper) and the 7 patients with combined NTCP reduction larger than 15% (lower).</p
Nomogram for tube feeding dependence to determine normal tissue complication probability (NTCP) values for each individual patient.
<p>Abbreviations: SF, conventional radiotherapy; ART, accelerated radiotherapy; CRT, chemoradiation.</p
Pre-treatment charactistics in the training cohort and test cohort.
<p>Abbreviations: 3D-CRT, Three Dimensional Conformal Radiotherapy; IMRT, Intensity-Modulated Radiation Therapy; RTOG, Radiation Therapy Oncology Group.</p
Results of the univariate logistic regression analysis with tube feeding dependence at 6 months (TUBE<sub>M6</sub>) as primary endpoint in patients included in the training cohort.
<p>Abbreviations: 3D-CRT, Three Dimensional Conformal Radiotherapy; IMRT, Intensity-Modulated Radiation Therapy; RTOG, Radiation Therapy Oncology Group; CI, Confidence Interval.</p
Results of the LASSO analysis with tube feeding dependence at 6 months (TUBE<sub>M6</sub>) as primary endpoint.
<p>Abbreviations: OR, Odds Ratio; CI, Confidence Interval; B, model coefficient beta.</p