43 research outputs found
Eating quality of beef from biotypes included in the PGI “Ternera Asturiana” showing distinct physicochemical characteristics and tenderization pattern
determine if their differences in physicochemical characteristics and tenderization pattern during
maturation (3 to 21 days) had an effect on the consumer evaluation of beef palatability. Biotype affected
significantly pH, water holding capacity, chemical composition (Pb0.001) and meat lightness (Pb0.05).
Ageing time affected significantly (Pb0.05) colour, meat toughness and sensory attributes in a different way
within each biotype. Multivariate analysis showed two different meat groups: 1) meat from mh-genotypes,
characterized by high juice losses, lightness (L*), protein content and high sensory acceptability at
intermediate (7 and 14 days) ageing times; 2) meat from rustic (AM) breed and biotypes free of myostatin
mutation (AV (+/+) and AV×AM), showing higher intramuscular fat, myoglobin content, and instrumental
toughness and requiring longer storage times (21 days). This should be taken into account for the proper
post-mortem management and commercialization of each product to achieve its best sensory quality
Electrochemical behavior of simetryn herbicide at water|1,2-dichloroethane interface
Herein, the electrochemical behavior of the simetryn herbicide at the water|1,2-dichloroethane interface was investigated by cyclic voltammetry and electrochemical impedance spectroscopy. Parameters such as transfer Gibbs energy, ionic partition coefficient, and the apparent rate constants across the interface were evaluated. According to the results, the ionic form of this herbicide is highly hydrophobic because Δw o G0 SIMH w→o + is 3.57 kJ mol−1 and logPSIMH 0 + is −0.622. In addition, the ionic partition diagram for this compound shows dual behavior as a function of pH: when pH pKa, simetryn serves as a mobile proton carrier across the interface. The present study offers some important insights that help in understanding the partitioning and kinetic processes of environmentally important molecules across biological membranes.Fil: Velázquez-Manzanares, Miguel. Universidad Autonoma de Coahuila; MéxicoFil: García Martínez, Humberto. Universidad Autonoma de Coahuila; MéxicoFil: Yudi, Lidia Mabel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Físico-química de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Instituto de Investigaciones en Físico-química de Córdoba; ArgentinaFil: Amador-Hernández, Judith. Universidad Autonoma de Coahuila; MéxicoFil: de la Garza Rodríguez, Iliana M.. Universidad Autonoma de Coahuila; MéxicoFil: Colunga Urbina, Edith M.. Universidad Autonoma de Coahuila; Méxic
Autophagy upregulation and loss of NF-kB in oxidative stress-related immunodeficient SAMP8 mice
Aged spleens from senescence-accelerated prone mice 8 (SAMP8) and senescence-accelerated resistant
mice 1 (SAMR1) were examined to determine whether sex or melatonin had an effect on oxidative
stress-related immune impairments. We observed that the immunosenescence of SAMP8 mice was
associated with a redox imbalance, leading to an age-related increase in oxidative damage, resulting
from a decrease in antioxidant defense and protease activity. Moreover, increased apoptotic cell death, a
decrease in proliferative activity and the loss of NF-kB activation were also related to the
immunodeficiency seen in SAMP8 compared to SAMR1 mice. Females demonstrated higher oxidative
stress-related alterations in the immune response, and subsequent, melatonin treatment provided the
best protective effects. Pathways involved in autophagy were upregulated in SAMP8 as an adaptive
response to oxidative stress, in an attempt to rescue the cell from increased apoptosis and age-related
immunodeficiency. However, the NF-kB signaling and autophagic processes were unaffected by
treatment with melatonin. Therefore, we propose a key role for NF-kB signaling and autophagy in the
oxidative stress-related immunosenescent spleens of SAMP8 mice