Looking westwards and worshipping: The New York 'Creative Revolution' and British advertising, 1956-1980

This article explores the ways in which developments associated with the ?creative revolution? in New York advertising in the 1950s and 1960s were imported into the United Kingdom, helping to reshape advertising practices in London. In locating the development of UK advertising within this history of commercial exchange, this article explores the modes of transmission and the material conduits through which innovations in advertising practice crossed the Atlantic. It also focuses on the role played by a distinctive 1960s formation of practitioners who used an organisation called the Design and Art Directors Association to champion the new idioms of US advertising. Their rise to influence helped to legitimate a new set of criteria for evaluating advertising which placed ?creativity? above ?research? and the ?science of selling? as the principal measure of good advertising. In exploring the exporting of the ?new advertising? to the United Kingdom, this article develops a particular understanding of how Anglo-American advertising relations worked to shape UK advertising practices. This foregrounds the way the US ?creative revolution?, like other forms of US advertising, was adapted, hybridised and indigenised in its importing to Britain. This article shows how the ?new advertising? pioneered in New York was reworked and combined with more local cultural influences. Out of this emerged distinctive styles of British advertising in the 1960s and 1970s

MFA13 (MFA 2013)

Catalogue of a culminating student exhibition held at the Mildred Lane Kemper Art Museum, May 3-July 29, 2013. Contents include Introduction / Buzz Spector -- The collaborative turn : new models of thinking, making, and learning / Patricia Olynyk -- [Introduction] / David Schuman -- Lyndon Barrois, Jr. / Rickey Laurentiis -- Sarah Bernhardt -- Shifting Shanghais / Hsuan Ying Chen -- Serhii Chrucky / JaNae Contag -- JaNae Contag / Emily Hanson -- Carrie DeBacker / Gabriel Feldman -- Erin M. Duhigg -- José Garza / Serhii Chrucky -- Eric Gray / Ariel Lewis -- Meghan Allynn Johnson : to or towards / Blair Allyn Johnson -- Hoa Le / Maria Xia -- Christine Eunji Lee -- Lavar Munroe : the black superhero when everyone was looking for the scapegoat / Patrick Johnson -- Jon A. Orosco : architectonics / Rickey Laurentiis -- Michael Powell / Nicholas Tamarkin -- Bridget A. Purcell : welcome home / Andy Chen -- Malahat Qureshi -- Natalie Rodgers / Katie McGinnis -- Carla Fisher Schwartz / Jennifer Padgett -- Zak Smoker -- Laurencia Strauss / Maura Pellettieri -- Lili Yang -- Vivian Zapata -- Contributors -- About the Sam Fox School.https://openscholarship.wustl.edu/books/1004/thumbnail.jp

Randomized factorial trial of esomeprazole and aspirin in Barrett’s oesophagus: the Aspirin and Esomeprazole Chemoprevention in Barrett’s metaplasia Trial (AspECT)

Background: Oesophageal adenocarcinoma (OA) is the sixth commonest cause of cancer death worldwide and Barrett’s oesophagus (BO) is the most significant risk factor. We evaluated the efficacy of high-dose esomeprazole proton pump inhibitor acid suppression (PPI) and aspirin in improving outcome for BO patients in the largest such randomized controlled trial. Methods: Patients with ≥1cm BO in UK and Canadian hospitals were randomized 1:1:1:1 using a computer-generated schedule held in a central trials unit in a 2X2 factorial design to high-dose (40mg twice-daily) or low-dose (20mg once-daily) PPI, alone or with aspirin (UK: 300mg/day, Canada: 325mg/day), unblinded (reporting pathologists blinded). The primary composite endpoint was time to all-cause mortality, OA, or high-grade dysplasia, analysed using accelerated failure time modelling adjusted for minimization factors (age, BO length, intestinal metaplasia). Findings: Recruited patients (N=2557) were followed for 8·9 years (median; interquartile range 8·2–9·8), collecting 20,095 follow-up years and 99·9% of planned data. There were 313 primary events. High-dose PPI was superior to low-dose PPI (p=0·037, N=1265 (low dose), N=1270 (high dose), time ratio (TR)=1·27, 95%CI=1·01–1·58). Aspirin was not significantly better than no aspirin (p=0·068, N=1142 (no aspirin), N = 1138 (aspirin), TR=1·24, 95%CI=0·98–1·57). If patients using NSAIDs were censored at time of first use,aspirin was significantly better than no Aspirin (p=0·043, N=2,236, TR=1·29 95%CI=1·01– 1·66). Combining high-dose PPI with aspirin had the strongest effect compared with low dose PPI without aspirin (p=0·0068, TR=1·59, 95%CI=1·14–2·23). NNT for PPI and aspirin benefit is 34 and 43, respectively. Only 1·0% (28) of participants reported study-treatment related serious adverse events. Interpretation: High-dose PPI and aspirin chemoprevention therapy, especially in combination, significantly and safely improve outcome in BO patients

Now I can see a train comin\u27 down the railroad track [first line of chorus]

Performers: Jimmie RodgersPiano, Voice and Chord

Listen to me mama while I sing you this song, listen to your [first line of chorus]

Performers: Jimmie RodgersPiano, Voice and Chord

The old pals are always the best you see good friends you find [first line of chorus]

Performers: Jimmie RodgersPiano, Voice and Chord

Away out on the mountain, away out on the mountain [first line of chorus]

Performers: Jimmie RodgersPiano, Voice and Chord

In that dear old sunny south by the sea that is where I\u27ll [first line of chorus]

Performance Medium: Piano, Voice and Chord

Genetic variation and population structure of moose (Alces alces) at neutral and functional DNA loci

Genetic variation was examined for moose (Alces alces) from Riding Mountain, Isle Royale, and Pukaskwa national parks; northwestern, Nipigon, northeastern, and central Ontario; New Brunswick; and Newfoundland. The national parks were identified as maintaining potentially different local selection pressures due to the absence of hunting and the presence or absence of the parasite Parelaphostrongylus tenuis. Genetic variation was estimated using neutral DNA markers, assessed by multilocus DNA fingerprinting and five microsatellite loci, and the functional antigen binding region (ARS) (exon 2) of the major histocompatibility complex (MHC) gene DRB. There was discordance in the allelic diversity observed at the neutral loci compared with the MHC DRB locus in a number of populations. Ontario populations demonstrated higher levels of variability at the neutral loci and relatively low levels at the DRB locus. Conversely, the Isle Royale population has the lowest genetic variability, consistent with a historic small founding event, at the neutral DNA markers and relatively high variability at the MHC gene. Relatively high levels of genetic variation at the DRB locus were observed in protected park populations concomitant with the absence of white-tailed deer (Odocoileus virginianus) or the parasite P. tenuis and an absence of hunting. Gene flow was observed among the neighboring geographic regions within Ontario, including Pukaskwa National Park, with evidence of isolation-by-distance among more distant regions within Ontario. The discordant patterns between DNA markers suggest that neutral DNA markers may not accurately reflect adaptive variation present at functional loci