Pretreatment with beta-blockers and the frequency of hypokalemia in patients with acute chest pain

Plasma potassium concentration was measured at admission in 1234 patients who presented with acute chest pain. One hundred and ninety five patients were on P blockers before admission. The potassium concentrations of patients admitted early (within four hours of onsetof symptoms) were compared with those admitted later (4-18 hours after onset of symptoms). There was a transient fall in plasma potassium concentrations in patients not pre-treated with , B blockers. This was not seen in patients who had been on P blockers before admission. Nonselective, B blockers were more effective than cardioselective agents in maintaining concentrationsof plasma potassium. These findings suggest a mechanism for the beneficial effects of ,B blockers on morbidity and mortality in acute myocardial infarction

Delayed Photoionization Feedback in a Super Star Cluster in SBS0335-052E

SBS0335-052 is a well studied Blue Compact Dwarf galaxy with one of the lowest metallicities of any known galaxy. It also contains 6 previously identified Super Star Clusters. We combine archival HST NICMOS images in the Pa alpha line and the 1.6 micron continuum of the eastern component, SBS0335-052E, with other space and ground based data to perform a multi-wavelength analysis of the super star clusters. We concentrate on the southern most clusters, designated S1 and S2, which appear to be the youngest clusters and are the strongest emitters of Pa alpha, radio, and x-ray flux. Our analysis leads to a possible model for S1 and perhaps S2 as a cluster of very young, massive stars with strong stellar winds. The wind density can be high enough to absorb the majority of ionizing photons within less than 1000 AU of the stars, creating very compact HII regions that emit optically thick radiation at radio wavelengths. These winds would then effectively quench the photoionizing flux very close to the stars. This can delay the onset of negative feedback by photoionization and photodissociation on star formation in the clusters. This is significant since SBS0335-052E resembles the conditions that were probably common for high redshift star formation in galaxies near the epoch of reionization.Comment: Accepted for publication in the Astrophysical Journa

Missing driver in the Sun–Earth connection from energetic electron precipitation impacts mesospheric ozone

Energetic electron precipitation (EEP) from the Earth’s outer radiation belt continuously affects the chemical composition of the polar mesosphere. EEP can contribute to catalytic ozone loss in the mesosphere through ionization and enhanced production of odd hydrogen. However, the long-term mesospheric ozone variability caused by EEP has not been quantified or confirmed to date. Here we show, using observations from three different satellite instruments, that EEP events strongly affect ozone at 60–80 km, leading to extremely large (up to 90%) short-term ozone depletion. This impact is comparable to that of large, but much less frequent, solar proton events. On solar cycle timescales, we find that EEP causes ozone variations of up to 34% at 70–80 km. With such a magnitude, it is reasonable to suspect that EEP could be an important part of solar influence on the atmosphere and climate syste

A Search for the Damped Ly-alpha Absorber at z=1.86 toward QSO 1244+3443 with NICMOS

We have carried out a high-resolution imaging search for the galaxy associated with the damped Lyman-alpha (DLA) absorber at z=1.859 toward the z_{em}=2.48 quasar QSO 1244+3443, using the HST and the NICMOS. Images were obtained in the broad filter F160W and the narrow filter F187N with camera 2 on NICMOS with the goal of detecting the rest-frame optical continuum and the H-alpha line emission from the DLA. After PSF subtraction, two weak features are seen at projected separations of 0.16-0.24" from the quasar. Parts of these features may be associated with the DLA absorber, although we cannot completely rule out that they could be artifacts of the point spread function (PSF). If associated with the DLA, the objects would be ~1-2 h_{70}^{-1} kpc in size with integrated flux densities of 2.5 and 3.3 mu Jy in the F160W filter, implying luminosities at lambda_{central}=5600 A in the DLA rest frame of 4.4-5.9 x 10^{9} h_{70}^{-2} L_{solar} at z=1.86, for q0=0.5. However, no significant H-alpha line emission is seen from these objects, suggesting low star formation rates (SFRs). Our 3 sigma upper limit on the SFR in the DLA is 1.3 h_{70}^{-2} M_{solar}/yr for q0 = 0.5 (2.4 h_{70}^{-2} M_{solar} yr^{-1} for q0 = 0.1). This together with our earlier result for LBQS 1210+1731 mark a significant improvement over previous constraints on the star formation rates of DLAs. A combination of low SFR and some dust extinction is likely to be responsible for the lack of H-alpha emission. Alternatively, the objects, may be associated with the quasar host galaxy. In any case, our observations suggest that the DLA is not a large bright proto-disk, but a compact object or a low-surface brightness galaxy. If the two features are PSF artifacts then the constraints on DLA properties are even more severe.Comment: 28 pages, 9 figures. Accepted for publication in The Astrophysical Journal. Figures are given at a slightly lower resolution here, to decrease file sizes. The higher resolution versions can be found in the Ap

‘If you look the part you’ll get the job’: should career professionals help clients to enhance their career image?

This article presents a critical exploration of the role of career professionals in supporting people to reflect on and enhance their appearance, attractiveness and self-presentation (career image). The article is conceptual and based on a review of the broader literature on career success, appearance and attractiveness. It explores the evidence for a relationship between attractiveness and career, and the authors propose a conceptual framework in which career image is comprised of three elements (interpersonal skills, aesthetic presentation and beauty). The paper examines a possible role for career professionals in relation to this and then critically examines this role and concludes with the proposition of a research agenda in this area

NICMOS Imaging of a Damped Lyman-alpha Absorber at z=1.89 toward LBQS 1210+1731 : Constraints on Size and Star Formation Rate

We report results of a high-resolution imaging search (in rest frame H-$\alpha$ and optical continuum) for the galaxy associated with the damped Lyman-$\alpha$ (DLA) absorber at $z=1.892$ toward the $z_{em}=2.543$ quasar LBQS 1210+1731, using HST/NICMOS. After PSF subtraction, a feature is seen in both the broad-band and narrow-band images, at a projected separation of 0.25\arcsec from the quasar. If associated with the DLA, the object would be $\approx 2-3$ $h_{70}^{-1}$ kpc in size with a flux of $9.8 \pm 2.4$ $\mu$Jy in the F160W filter, implying a luminosity at $\lambda_{central}=5500$ {\AA} in the rest frame of $1.5 \times 10^{10}$ $h_{70}^{-2}$ L$_{\odot}$ at $z=1.89$, for $q_{0}=0.5$. However, no significant H-$\alpha$ emission is seen, suggesting a low star formation rate (SFR) (3 $\sigma$ upper limit of 4.0 $h_{70}^{-2}$ M$_{\odot}$ yr$^{-1}$), or very high dust obscuration. Alternatively, the object may be associated with the host galaxy of the quasar. H-band images obtained with the NICMOS camera 2 coronagraph show a much fainter structure $\approx 4-5$ $h_{70}^{-1}$ kpc in size and containing four knots of continuum emission, located 0.7\arcsec away from the quasar. We have probed regions far closer to the quasar sight-line than in most previous studies of high-redshift intervening DLAs. The two objects we report mark the closest detected high-redshift DLA candidates yet to any quasar sight line. If the features in our images are associated with the DLA, they suggest faint, compact, somewhat clumpy objects rather than large, well-formed proto-galactic disks or spheroids.Comment: 52 pages of text, 19 figures, To be published in Astrophysical Journal (accepted Dec. 8, 1999

Organic-Silica Interactions in Saline:Elucidating the Structural Influence of Calcium in Low-Salinity Enhanced Oil Recovery

Abstract Enhanced oil recovery using low-salinity solutions to sweep sandstone reservoirs is a widely-practiced strategy. The mechanisms governing this remain unresolved. Here, we elucidate the role of Ca2+ by combining chemical force microscopy (CFM) and molecular dynamics (MD) simulations. We probe the influence of electrolyte composition and concentration on the adsorption of a representative molecule, positively-charged alkylammonium, at the aqueous electrolyte/silica interface, for four electrolytes: NaCl, KCl, MgCl2, and CaCl2. CFM reveals stronger adhesion on silica in CaCl2 compared with the other electrolytes, and shows a concentration-dependent adhesion not observed for the other electrolytes. Using MD simulations, we model the electrolytes at a negatively-charged amorphous silica substrate and predict the adsorption of methylammonium. Our simulations reveal four classes of surface adsorption site, where the prevalence of these sites depends only on CaCl2 concentration. The sites relevant to strong adhesion feature the O− silica site and Ca2+ in the presence of associated Cl−, which gain prevalence at higher CaCl2 concentration. Our simulations also predict the adhesion force profile to be distinct for CaCl2 compared with the other electrolytes. Together, these analyses explain our experimental data. Our findings indicate in general how silica wettability may be manipulated by electrolyte concentration