Polarization mode dispersion compensator field trial and field fiber characterization

Two high-PMD long distance routes were characterized and used to test an optical polarization mode dispersion compensator (PMDC) under field conditions. For this trial, 110 km routes with mean PMD values of 25 and 26.5 ps were provisioned with commercial WDM transport equipment and tested for several weeks. The route was comprised of three spans of characterized fiber that followed railroad tracks. We show the temporal variation of the output polarization state and the evolution of first- and second-order PMD spectra over 7 days. The deployment of a variable-length PMDC on these links allowed error-free transmission of an OC-192 signal. Splitting the output to receivers with and without PMDC demonstrated specific PMD events that caused errors in the absence of a PMDC. (C) 2002 Optical Society of America

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead