Correlation between CD68 (a) count or CD 163 (b) count and OS in both surgery and non-surgery groups.

<p>The CD68 count does not correlate with OS (Pearson r -0.07, p = 0.81), the CD163 count shows an inverse trend with OS (Pearson r -0.33, p = 0.22).</p

Tumor derived factors influence macrophages towards a M2 phenotype to varying degrees.

<p>Relative mRNA expression levels of IL-10 (a), CD163 (b), CD80 (c), HLA-DR (d), PD-L1 (e), and Arginase-1/iNOS (NOS2) ratio (f) in macrophages cultured in six mesothelioma cell line conditioned media (T1 - T6) compared to standard M1 and M2 conditions.</p

Representative images of CD68 (a) and CD163 (b) staining in the tumor biopsy of one MPM patient.

<p>Representative images of CD68 (a) and CD163 (b) staining in the tumor biopsy of one MPM patient.</p

Patient characteristics.

<p>Patient characteristics.</p

Representative image of CD8 staining in the tumor biopsy of one MPM patient.

<p>Representative image of CD8 staining in the tumor biopsy of one MPM patient.</p

Correlation between CD163/CD68 ratio in tumor in both surgery and non-surgery patients and OS.

<p>This ratio is significantly negatively correlated with OS in the total patient group (Pearson r -0.72, p<0.05).</p