4,808 research outputs found
PROBLEMATIKA HUKUM PEMBAGIAN WARIS 2:1 DALAM PENDEKATAN TEORI QATH’I ZHANNI
In inheritance law of Islam, the Qur’an has idealized and specified clearly that sons inherit twice that of daughters. Instead of legal practice some communities in Indonesia that the sons received the same parts with the daughters. Even dividing when the heir is still alive because their lack of understanding of the text qath’i zhani. Qath’i al-dalalah Islamic inheritance texts about the distribution of 2: 1 between sons and daughters, according to the ulama not absolutely necessary, as the opinion of Munawir Sjadazali. Thus it was stated by Mashdar Farid Mas'udin, that the qath’i was only the principles of justice are conceived by the verses of the Islamic inheritance and not the provisions of section men who got twice that of women. But this kind of division has implications for the strength of law, if there is a dispute in the future then it is incapable to be accountable because distribution is outside of the provisions of the Qur'an and Law and also, this sort of thing would have implications for the impartial justice in Islamic inheritance law of the balance between the rights of the estate obtained by the obligations or burdens that must be borne or fulfilled among the heirs. Therefore, the sense of justice in Islamic inheritance law is not measured by the similarity degree between the heirs, but is determined based on the large-small burden or responsibility entrusted to them, in terms of generality state/human life
Analysis of X-inactivation status in a Rett syndrome natural history study cohort
BACKGROUND: Rett syndrome (RTT) is a rare neurodevelopmental disorder associated with pathogenic MECP2 variants. Because the MECP2 gene is subject to X-chromosome inactivation (XCI), factors including MECP2 genotypic variation, tissue differences in XCI, and skewing of XCI all likely contribute to the clinical severity of individuals with RTT.
METHODS: We analyzed the XCI patterns from blood samples of 320 individuals and their mothers. It includes individuals with RTT (n = 287) and other syndromes sharing overlapping phenotypes with RTT (such as CDKL5 Deficiency Disorder [CDD, n = 16]). XCI status in each proband/mother duo and the parental origin of the preferentially inactivated X chromosome were analyzed.
RESULTS: The average XCI ratio in probands was slightly increased compared to their unaffected mothers (73% vs. 69%, p = .0006). Among the duos with informative XCI data, the majority of individuals with classic RTT had their paternal allele preferentially inactivated (n = 180/220, 82%). In sharp contrast, individuals with CDD had their maternal allele preferentially inactivated (n = 10/12, 83%). Our data indicate a weak positive correlation between XCI skewing ratio and clinical severity scale (CSS) scores in classic RTT patients with maternal allele preferentially inactivated XCI (r
CONCLUSION: These results extend our understanding of the pathogenesis of RTT and other syndromes with overlapping clinical features by providing insight into the both XCI and the preferential XCI of parental alleles
Enhancing BER performance limit of BCH and RS codes using multipath diversity
Modern wireless communication systems suffer from phase shifting and, more importantly, from interference caused by multipath propagation. Multipath propagation results in an antenna receiving two or more copies of the signal sequence sent from the same source but that has been delivered via different paths. Multipath components are treated as redundant copies of the original data sequence and are used to improve the performance of forward error correction (FEC) codes without extra redundancy, in order to improve data transmission reliability and increase the bit rate over the wireless communication channel. For a proof of concept Bose, Ray-Chaudhuri, and Hocquenghem (BCH) and Reed-Solomon (RS) codes have been used as FEC to compare their bit error rate (BER) performances. The results showed that the wireless multipath components significantly improve the performance of FEC. Furthermore, FEC codes with low error correction capability and employing the multipath phenomenon are enhanced to perform better than FEC codes which have a bit higher error correction capability and did not utilise the multipath. Consequently, the bit rate is increased, and communication reliability is improved without extra redundancy
Spontaneous and stimulated emission tuning characteristics of a Josephson junction in a microcavity
We have investigated theoretically the tuning characteristics of a Josephson
junction within a microcavity for one-photon spontaneous emission and for
one-photon and two-photon stimulated emission. For spontaneous emission, we
have established the linear relationship between the magnetic induction and the
voltage needed to tune the system to emit at resonant frequencies. For
stimulated emission, we have found an oscillatory dependence of the emission
rate on the initial Cooper pair phase difference and the phase of the applied
field. Under specific conditions, we have also calculated the values of the
applied radiation amplitude for the first few emission maxima of the system and
for the first five junction-cavity resonances for each process. Since the
emission of photons can be controlled, it may be possible to use such a system
to produce photons on demand. Such sources will have applications in the fields
of quantum cryptography, communications and computation
Knowledge and Health Beliefs Regarding Sickle Cell Disease Among Omanis in a Primary Healthcare Setting : Cross-sectional study
Objectives: Sickle cell disease (SCD) is a global health concern associated with high childhood morbidity and mortality; in Oman, the prevalence of SCD is 0.2%. Public awareness of SCD and the need for premarital screening (PMS) are essential to reduce the incidence of this disease. This study aimed to assess awareness of and beliefs regarding SCD and PMS among Omanis in a primary healthcare setting. Methods: This cross-sectional study took place in five health centres located in Al-Seeb Province, Muscat, Oman, between June and August 2015. A total of 500 Omanis aged ≥18 years old attending the clinics were invited to participate in the study. A previously described questionnaire by Gustafson et al. was used to measure awareness of and beliefs regarding SCD and PMS. Results: A total of 450 Omani adults completed the questionnaire (response rate: 90.0%). The majority (67.8%) were aware that SCD is genetically inherited and 85.1% believed in the value of PMS; however, only 24.4% reported having undergone PMS previously. Few participants were aware that SCD can be very painful (20.2%) and can cause strokes, infections and organ damage (20.0%). More than half (56.7%) reported that the availability of educational material on SCD or PMS in Oman was inadequate. Participants’ education levels were positively associated with accurate SCD knowledge (P <0.05). Conclusion: Despite the free availability of PMS services in local health centres, few Omanis reported having undergone PMS previously. Health promotion and education programmes are therefore needed in Oman in order to increase public awareness of SCD and the value of PMS
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