Addressing the ethics of telepresence applications through end-user engagement

Portacolone et al.’s Ethics Review highlights the ethical challenges associated with the implementation of telepresence devices and applications in the context of aging and dementia. In this response, we review ethical considerations as they relate to specific modalities of telepresence, with an emphasis on the continuum of potential interaction agents, from known individuals to fully automated and intelligent interlocutors. We further discuss areas in need of empirical evidence to inform regulatory efforts in telepresence. We close with a call for meaningful end-user engagement at all stages of technology development

Socially assistive robots as mental health interventions for children : a scoping review

Socially Assistive Robots are promising in their potential to promote and support mental health in children. There is a growing number of studies investigating the feasibility and effectiveness of robot interventions in supporting children’s mental wellbeing. Although preliminary evidence suggests that Socially Assistive Robots may have the potential to help address concerns such as stress and anxiety in children, there is a need for a greater focus in examining the impact of robotic interventions in this population. In order to better understand the current state of the evidence in this field and identify critical gaps, we carried out a scoping review of the available literature examining how social robots are investigated as means to support mental health in children. We identified existing types of robot intervention and measures that are being used to investigate specific mental health outcomes. Overall, our findings suggest that robot interventions for children may positively impact mental health outcomes such as relief of distress and increase positive affect. Results also show that the strength of evidence needs to be improved to determine what types of robotic interventions could be most effective and readily implemented in pediatric mental health care. Based on our findings, we propose a set of recommendations to guide further research in this area

Dithiols and monothiols are linked with GABA transport in membrane vesicles of rat brain synaptosomes

The properties of γ-aminobutyric acid (GABA) transport into membrane vesicles derived from synaptosomes of rat brain have been studied using membrane-permeable and -impermeable sulfhydryl reagents, dithiol-specific reagents and oxidizing reagents. GABA transport is inhibited, reversibly, by very low concentrations of the membrane-permeable trivalent arsenical, phenylarsine oxide. Preincubation with this reagent only partially protects GABA transport from inactivation by N-ethylmaleimide (NEM). Thorin, a negatively charged trivalent arsenical, has no influence on GABA transport at concentrations 100-fold higher than that of the inhibitory phenylarsine oxide. The impermeant oxidizing agent, potassium ferricyanide, did not inhibit transport whereas the permeant reagent, diamide, was inhibitory. These data indicate that the GABA transporter possesses an activity-linked dithiol in a hydrophobic region of the carrier not accessible to charged, polar reagents. p-Chloromercuribenzenesulfonate (PCMBS) also inhibits but does not protect against NEM inactivation, suggesting the occurrence of an activity-linked monothiol in a polar region of the carrier.

Native oxide limited cross-plane thermal transport in suspended silicon membranes revealed by scanning thermal microscopy

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Scanning thermal microscopy and nanoscale heat transfer

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