6,313 research outputs found
Phase II, open-label study of brivanib as first-line therapy in patients with advanced hepatocellular carcinoma
The Dangerous Intersection between Race, Class and Stand Your Ground
The Stand Your Ground (SYG) law has and will likely continue to generate a wealth of controversy and political debate. It derives its historical significance from the Castle doctrine that allows citizens to protect themselves. The aftermath of SYG has led to an increase in justifiable homicides of minority victims. A preliminary analysis of data from FBI Uniform Crime Reports suggests that the race of the victim is the foremost determinant in the outcome of SYG cases where the perpetrator is non-minority. This research will further explore the Castle doctrine and examine SYG laws in Florida where racial tension is a challenge to determine if there has been an increase in the death of persons of color, especially Black male youths since the lawās enactment. Finally, it will use policy analysis methodology to identify the problem, underlying assumptions, implementation structure, rationales, and to forecast the policy implications of the law
Design and performance of a multicentre, randomized controlled trial of teleconsulting.
We have designed and performed a multicentre, randomized controlled trial of teleconsulting. The trial investigated the effectiveness and cost implications in rural and inner-city settings of using videoconferencing as an alternative to general practitioner referral to a hospital specialist. The participating general practitioners referred a total of 3170 patients who satisfied the entry criteria. Of these, 1040 (33%) failed to provide consent or otherwise refused to participate in the trial. Of the patients recruited to the trial, a total of 1902 (91%) completed and returned the baseline questionnaire. Although the trial was successful in recruiting sufficient patients and in obtaining high questionnaire response rates, the findings will require careful interpretation to take account of the limits which the protocol placed on the ability of general practitioners to select patients for referral
Assignment of the excess absorption underlying the SchumannāRunge bands of molecular oxygen
A long-standing problem, pertaining to the origin of the excess absorption found experimentally to underlie the high-vibrational SchumannāRunge bands of molecular oxygen, is resolved. Through new calculations, with parameter sets based on recently obtained experimental information, it is shown that the excess absorption arises from transitions into the lowest valence states of Ā³Ī u and Ā³Ī g symmetry
A Creative Writing Case Study of Gender-Based Violence in Coach Education: Staceyās Story
Creative nonfiction writing is the literary technique employed in this article to explore insights and assist our understanding of an āallegedā sexual assault in a sport coach education environment. Creative nonfiction employs various narrative tools: characters, setting, figurative language, sequences of events, plot, sub-plot, and dialogue, designed to render the sensitive and controversial elements of sexual assault significant. Readers are, therefore, invited to engage with Staceyās Story and reflect on the actions of both the perpetrator(s) and the victim. While there are risks associated with the sharing of stories, especially those which are considered dangerous, it is envisaged that Staceyās Story will be viewed as an opportunity to develop more critical responses and advance our understanding of gender-based violence in sport
Virtual outreach: economic evaluation of joint teleconsultations for patients referred by their general practitioner for a specialist opinion
Objectives To test the hypotheses that, compared with conventional outpatient consultations, joint teleconsultation (virtual outreach) would incur no increased costs to the NHS, reduce costs to patients, and reduce absences from work by patients and their carers.Design Cost consequences study alongside randomised controlled trial.Setting Two hospitals in London and Shrewsbury and 29 general practices in inner London and Wales.Participants 3170 patients identified; 2094 eligible for inclusion and willing to participate. 1051 randomised to virtual outreach and 1043 to standard outpatient appointments.Main outcome measures NHS costs, patient costs, health status (SF-12), time spent attending index consultation, patient satisfaction.Results Overall six month costs were greater for the virtual outreach consultations (pound724 per patient) than for conventional outpatient appointments (pound625): difference in means pound99 ($162; is not an element of138) (95% confidence interval pound10 to pound187, P=0.03). if the analysis is restricted to resource items deemed "attributable" to the index consultation, six month costs were still greater for virtual outreach: difference in means pound108 (pound73 to pound142, P < 0.0001). In both analyses the index consultation accounted for the excess cost. Savings to patients in terms of costs and time occurred in both centres: difference in mean total patient cost 8 pound (5 pound to 10 pound, P < 0.0001). Loss of productive time was less in the virtual outreach group: difference in mean cost pound11 (pound10 to pound12, P < 0.0001).Condusion The main hypothesis that virtual outreach would be cost neutral is rejected, but the hypotheses that costs to patients and losses in productivity would be lower are supported
The failed liberalisation of Algeria and the international context: a legacy of stable authoritarianism
The paper attempts to challenge the somewhat marginal role of international factors in the study of transitions to democracy. Theoretical and practical difficulties in proving causal mechanisms between international variables and domestic outcomes can be overcome by defining the international dimension in terms of Western dominance of world politics and by identifying Western actions towards democratising countries. The paper focuses on the case of Algeria, where international factors are key in explaining the initial process of democratisation and its following demise. In particular, the paper argues that direct Western policies, the pressures of the international system and external shocks influence the internal distribution of power and resources, which underpins the different strategies of all domestic actors. The paper concludes that analysis based purely on domestic factors cannot explain the process of democratisation and that international variables must be taken into more serious account and much more detailed
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