Meaningful* percentage temporal changes in absolute intake of food group consumption in grams of secular trends in all reporters and plausible energy reporters in the 1) “healthy”, 2) “mixed” and 3) “western” patterns.

<p>Only groups of food are included, which had meaningful changes. The analysis was unadjusted for population differences between the two surveys in age, sex, smoking and physical activity. The unhealthy perceived food groups go first, the healthy food groups are in continuation. A positive value means an increase from the REGICOR 2000 to the REGICOR 2005 and a negative value means a decrease from the REGICOR 2000 to the REGICOR 2005. White—all reporters, black—plausible energy reporters. *≥15% change in food group consumption compared between the REGICOR 2000 and the REGICOR 2005 surveys.</p

Impact of a Partial Smoke-Free Legislation on Myocardial Infarction Incidence, Mortality and Case-Fatality in a Population-Based Registry: The REGICOR Study

<div><h3>Background and Objective</h3><p>Coronary heart disease (CHD) is the leading cause of death, and smoking its strongest modifiable risk factor. Our aim was to determine the impact of the Spanish 2006 partial smoke-free legislation on acute myocardial infarction (AMI) incidence, hospitalization and mortality rates, and 28-day case-fatality in Girona, Spain.</p> <h3>Methods</h3><p>Using a population-based registry (the REGICOR Study), we compared population incidence, hospitalization, and mortality rates, and 28-day case-fatality in the pre- and post-ban periods (2002–2005 and 2006–2008, respectively) by binomial regression analysis adjusted for confounding factors. We also analyzed the ban's impact on the outcomes of interest using the AMI definitions of the American Heart Association (AHA)/European Society of Cardiology (ESC) and the World Health Organization (WHO)-Monitoring trends and determinants in cardiovascular diseases (MONICA).</p> <h3>Results</h3><p>In the post-ban period, AMI incidence and mortality rates significantly decreased (relative risk [RR] = 0.89; 95% confidence interval [CI] = 0.81–0.97 and RR = 0.82; 95% CI = 0.71–0.94, respectively). Incidence and mortality rates decreased in both sexes, especially in women, and in people aged 65–74 years. Former and non-smokers (passive smokers) showed diminished incidence rates. Implementation of the ban was not associated with AMI case-fatality. Models tended to be more significant with the WHO-MONICA than with the AHA/ESC definition.</p> <h3>Conclusions</h3><p>The 2006 Spanish partial smoke-free legislation was associated with a decrease in population AMI incidence and mortality, particularly in women, in people aged 65–74 years, and in passive smokers. These results clarify the association between AMI mortality and the enactment of a partial smoke-free legislation and reinforce the effectiveness of smoking regulations in preventing CHD.</p> </div

Annual AMI incidence, hospitalization and mortality rates and 28-day case-fatality by age group or sex, in 2002–2008, according to the AHA/ESC AMI definition.

<p><i>AMI</i> acute myocardial infarction, <i>AHA</i> American Heart Association, <i>ESC</i> European Society of Cardiology.</p

Characteristics of patients with AMI in Girona Province (Spain), in 2002–2008, according to the AHA/ESC AMI definition.

<p><i>AMI</i> acute myocardial infarction, <i>AHA</i> American Heart Association, <i>ESC</i> European Society of Cardiology, <i>SD</i> Standard deviation.</p

RR and 95% CI for AMI mortality and 28-day case-fatality comparing the period after to the period before the 2006 partial smoke-free legislation enactment, according to the AHA/ESC AMI definition.

<p><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0053722#s3" target="_blank">Results</a> from negative binomial regression analysis.</p>*<p>p-value<0.05.</p><p><i>RR</i> relative risk, <i>CI</i> confidence interval, <i>AMI</i> acute myocardial infarction, <i>AHA</i> American Heart Association, <i>ESC</i> European Society of Cardiology.</p

Annual AMI incidence and mortality crude rates by sex and age group.

<p>Time trend of the 2002–2008 AMI incidence and mortality crude rates according to the AHA/ESC AMI definition. Annual rates are plotted in the middle of each year. A vertical bar in 2006 indicates the start of the partial smoke-free legislation. Upper left panel: AMI incidence in women, upper right panel: AMI mortality in women, lower left panel: AMI incidence in men, lower right panel: AMI mortality in men. Abbreviations: <i>AMI</i> acute myocardial infarction, <i>AHA</i> American Heart Association, <i>ESC</i> European Society of Cardiology.</p

Additional file 2: of Interatrial block and atrial remodeling assessed using speckle tracking echocardiography

Table S2. Matrix of correlations between P-wave duration on ECG, Doppler- echocardiographic and strain variables. Correlation between continuous variables: P-wave duration on ECG, Doppler- echocardiographic and strain variables. (DOC 41 kb

Additional file 1: of Interatrial block and atrial remodeling assessed using speckle tracking echocardiography

Table S1. Clinical and Doppler-echocardiographic characteristics. Clinical and transthoracic echocardiography characteristics of the patients included in this study. (DOC 47 kb

Additional file 3: of Interatrial block and atrial remodeling assessed using speckle tracking echocardiography

Table S3. Peak left atrial longitudinal strain rate in booster pump function phase in tertiles. Mantel Haenszel Test for tendencies of peak left atrial longitudinal strain rate in booster pump function phase. (DOC 34 kb

Sociodemographic and clinical characteristics of study participants.

<p>Sociodemographic and clinical characteristics of study participants.</p