Additional file 3: of RNS60 exerts therapeutic effects in the SOD1 ALS mouse model through protective glia and peripheral nerve rescue

Figure S3. A-D) Representative images of LSC micrographs stained with S100β (green) and GFAP (red) at 20 weeks of age. Scale bar: 20 μm. E) Quantification of immunofluorescence showed no differences between the two transgenic groups. Bar graphs represents mean ± SEM, (n = 5 animals per group); One-way ANOVA followed by post hoc Fisher’s LSD non-parametric test (p = 0.420). (DOCX 1342 kb

Additional file 2: of RNS60 exerts therapeutic effects in the SOD1 ALS mouse model through protective glia and peripheral nerve rescue

Figure S2. Representative immunoblot for GFAP performed on ventral portion of LSC of NTG mice or transgenic mice treated with NS or RNS60, at 20 weeks of age, and relative quantification. Data are expressed as mean ± SEM, (n = 5 animals per group). Data were statistically analyzed using one way ANOVA followed by post hoc Fisher’s LSD. * = p < 0.05, ** = p < 0.01, *** = p < 0.001, n.s. = non significant. (DOCX 162 kb