53,506 research outputs found
Government Transfer Payments and Strike Activity: Reforming Public Policy
[Excerpt] One of the most controversial labor policy issues is whether strikers should be eligible for government transfer payments, such as unemployment compensation, public assistance, and food stamps. The controversy often focuses on whether payment of such benefits to strikers increases the magnitude of strike activity. In this article, we argue that that is the wrong focus. The key issue is not whether strikers receive benefits, but who finances them. We contend that to the extent that the benefits are financed by the parties to the conflict (the employer and union), the transfers will not affect strike activity. This article extends our recent book on this topic, by briefly describing current and past policies, summarizing our argument for why financing is key, and presenting a proposal for reforming strike-related government transfers
Target shape dependence in a simple model of receptor-mediated endocytosis and phagocytosis
Phagocytosis and receptor-mediated endocytosis are vitally important particle
uptake mechanisms in many cell types, ranging from single-cell organisms to
immune cells. In both processes, engulfment by the cell depends critically on
both particle shape and orientation. However, most previous theoretical work
has focused only on spherical particles and hence disregards the wide-ranging
particle shapes occurring in nature, such as those of bacteria. Here, by
implementing a simple model in one and two dimensions, we compare and contrast
receptor-mediated endocytosis and phagocytosis for a range of biologically
relevant shapes, including spheres, ellipsoids, capped cylinders, and
hourglasses. We find a whole range of different engulfment behaviors with some
ellipsoids engulfing faster than spheres, and that phagocytosis is able to
engulf a greater range of target shapes than other types of endocytosis.
Further, the 2D model can explain why some nonspherical particles engulf
fastest (not at all) when presented to the membrane tip-first (lying flat). Our
work reveals how some bacteria may avoid being internalized simply because of
their shape, and suggests shapes for optimal drug delivery.Comment: 18 pages, 5 figure
Can Foreign Aid Buy Investment? Appropriation Through Conflict
The failure of foreign aid to promote growth in the developing world has received significant attention as evidence suggests that foreign aid does not translate into investment. This research has demonstrated that poor institutions in these developing economies (particularly with respect to property rights) results in an inability to fully appropriate the return to one’s investment, thereby serving as a prominent disincentive to investment. This paper presents an experimental test of a a 2-player, one-shot game of conflict in which we vary the strength of property rights. Our results suggest that stronger property rights reduce conflict and increase investment. In addition, we test the conventional wisdom that technological progress can increase the effectiveness of aid in stimulating investment. Contrary to intuition, we find technological progress has practically no effect on investment and that this failure to stimulate investment is largely due to deficiencies in property right institutions. Key Words: Property Rights; Conflict; Investment; Foreign Aid; Experiments
Solving Systems of Non-Linear Equations by Broyden's Method with Projected Updates
We introduce a modification of Broyden's method for finding a zero of n nonlinear equations in n unknowns when analytic derivatives are not available. The method retains the local Q-superlinear convergence of Broyden's method and has the additional property that if any or all of the equations are linear, it locates a zero of these equations in n+1 or fewer iterations. Limited computational experience suggests that our modification often improves upon Eroyden's method.
Technological Development and Medical Productivity: The Diffusion of Angioplasty in New York State
A puzzling feature of many medical innovations is that they simultaneously appear to reduce unit costs and increase total costs. We consider this phenomenon by examining the diffusion of percutaneous transluminal coronary angioplasty (PTCA) -- a treatment for coronary artery disease -- over the past two decades. We find that growth in the use of PTCA led to higher total costs despite its lower unit cost. Over the two decades following PTCA's introduction, however, we find that the magnitude of this increase was reduced by between 10% and 20% due to the substitution of PTCA for CABG. In addition, the increased use of PTCA appears to be a productivity improvement. PTCAs that substitute for CABG cost less and have the same or better outcomes, while PTCAs that replace medical management appear to improve health by enough to justify the cost.
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