Competitive Actions Of New Technology Firms The Red Queen Effect And New Firm Performance

The competitive strategy used by a new firm may be the most important strategy it ever employs (Covin & Slevin, 1989; Ferrier, 2001). A well-chosen and executed firm strategy is essential for a firm to realize its potential competitive advantage (Porter, 1981). A firm‘s strategic intent and resulting competitive actions are especially important when firms are new and vulnerable as they strive to learn which strategic actions help them adapt to their rivals actions and to their environment (Stinchcombe, 1965). Further, the competitive actions that new firms choose to take with rival firms affects the overall competitive dynamics of their industry (Smith, Ferrier, and Ndofor, 2001). One way to explore how the competitive actions of new firms affect their future is to capture and examine their individual competitive moves and countermoves over time (Smith, Grimm, Gannon, & Chen, 1991). Red Queen competition is a particular form of competitive dynamics that is well-suited to explore these issues of new rival firms (Barnett, 2008). Barnett and Sorenson (2002) suggested that competition and learning reinforce one another as organizations develop, and this is what van Valen (1973) referred to as the ‗Red Queen.‘ This definition of the Red Queen led to the development of the concept of Red Queen competition and the Red Queen effect. The competitive strategies these new firms use to obtain resources as they adapt, in particular how these firms compete and or cooperate, are key competitive strategies that remain understudied to-date (Amit, Glosten, and Muller, 1990). I explore Red Queen competition, and the ensuing Red Queen Effect, in a complex environmental setting that represents a high technology ecosystem (Arned, 1996, 2010; Iansiti & Levien, 2004a, 2004b; Moore, 1993; Pierce, 2009). New firms in such an ecosystem represent a particularly salient combination of type of firm, firm lifecycle period, and firm environment to iii examine strategic actions since these firms comprise a significant portion of the high-growth and future of our global economy (Stangler, 2010). Further, due to their need to rapidly adapt in a complex ecosystem, these firms rely heavily on short-lived information resources for competitive advantage (Barney, 1991; Nelson and Winter, 1982; Omerzel, 2008). To place this research in context, I consider the moderating effects of key environmental ecosystem resource conditions (Dess & Beard, 1984; Miller & Friesen, 1983; Sharfman & Dean, 1991). Empirical studies to-date have yielded mixed results and left unanswered questions about the basic components and the effects of Red Queen competition. To address these issues I explore this literature in chapter one of the dissertation, and in chapter two I develop a theoretical model of Red Queen competition that draws on the available empirical and theoretical literature to-date. Due to the mixed finding from the empirical results, I develop a precise agent-based simulation model of Red Queen competition in chapter three to facilitate data collection. Using this data I test a series of hypotheses designed to explore the fundamentals of Red Queen competition, specifically how escalating competitive activity for resources among new firms impacts their survival and performance. In addition, the moderating effect of environmental changes on Red Queen competition is also tested to explore the affect of context on Red Queen competition. Chapter four explains the findings from these hypotheses, future research directions, implications and limitations from the research, and my concluding thought

National Institute of Neurological Disorders and Stroke (NINDS): Advances in understanding and treating neuropathy, 24–25 October 2006; Bethesda, Maryland

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/75348/1/j.1529-8027.2008.00154.x.pd

Ptychographic hyperspectral spectromicroscopy with an extreme ultraviolet high harmonic comb

We demonstrate a new scheme of spectromicroscopy in the extreme ultraviolet (EUV) spectral range, where the spectral response of the sample at different wavelengths is imaged simultaneously. It is enabled by applying ptychographical information multiplexing (PIM) to a tabletop EUV source based on high harmonic generation, where four spectrally narrow harmonics near 30 nm form a spectral comb structure. Extending PIM from previously demonstrated visible wavelengths to the EUV/X-ray wavelengths promises much higher spatial resolution and more powerful spectral contrast mechanism, making PIM an attractive spectromicroscopy method in both the microscopy and the spectroscopy aspects. Besides the sample, the multicolor EUV beam is also imaged in situ, making our method a powerful beam characterization technique. No hardware is used to separate or narrow down the wavelengths, leading to efficient use of the EUV radiation

Scan time reduction for readout-segmented EPI using simultaneous multislice acceleration: Diffusion-weighted imaging at 3 and 7 Tesla

Purpose: Readout‐segmented echo‐planar imaging (rs‐EPI) can provide high quality diffusion data because it is less prone to distortion and blurring artifacts than single‐shot echo‐planar imaging (ss‐EPI), particularly at higher resolution and higher field. Readout segmentation allows shorter echo‐spacing and echo train duration, resulting in reduced image distortion and blurring, respectively, in the phase‐encoding direction. However, these benefits come at the expense of longer scan times because the segments are acquired in multiple repetitions times (TRs). This study shortened rs‐EPI scan times by reducing the TR duration with simultaneous multislice acceleration. Methods: The blipped‐CAIPI method for slice acceleration with reduced g‐factor SNR loss was incorporated into the diffusion‐weighted rs‐EPI sequence. The rs‐ and ss‐EPI sequences were compared at a range of resolutions at both 3 and 7 Tesla in terms of image fidelity and diffusion postprocessing results. Results: Slice‐accelerated clinically useful trace‐weighted images and tractography results are presented. Tractography analysis showed that the reduced artifacts in rs‐EPI allowed better discrimination of tracts than ss‐EPI. Conclusion: Slice acceleration reduces rs‐EPI scan times providing a practical alternative to diffusion‐weighted ss‐EPI with reduced distortion and high resolution. Magn Reson Med 74:136–149, 2015

Hypothenar hammer syndrome: Proposed etiology

AbstractPurpose: Finger ischemia caused by embolic occlusion of digital arteries originating from the palmar ulnar artery in a person repetitively striking objects with the heel of the hand has been termed hypothenar hammer syndrome (HHS). Previous reports have attributed the arterial pathology to traumatic injury to normal vessels. A large experience leads us to hypothesize that HHS results from trauma to intrinsically abnormal arteries. Methods: We reviewed the arteriography, histology, and clinical outcome of all patients treated for HHS in a university clinical research center study of hand ischemia, which prospectively enrolled more than 1300 subjects from 1971 to 1998. Results: Twenty-one men had HHS. All had occupational (mechanic, carpenter, etc) or avocational (woodworker) exposure to repetitive palmar trauma. All patients underwent upper-extremity and hand arteriography, unilateral in eight patients (38%) and bilateral in 13 patients (62%). By means of arteriogram, multiple digital artery occlusions were shown in the symptomatic hand, with either segmental ulnar artery occlusion in the palm or characteristic “corkscrew” elongation, with alternating stenoses and ectasia. Similar changes in the contralateral asymptomatic (and less traumatized) hand were shown by means of 12 of 13 bilateral arteriograms (92%). Twenty-one operations, consisting of segmental ulnar artery excision in the palm and vein grafting, were performed on 19 patients. Histology was compatible with fibromuscular dysplasia with superimposed trauma. Patency of arterial repairs at 2 years was 84%. One patient (5%) required amputative debridement of necrotic finger tips. No other tissue loss occurred. There have been no recurrences of ischemia in patients with patent bypass grafts. Conclusion: To our knowledge, this is the largest reported group of HHS patients. The characteristic angiographic appearance, histologic findings, and striking incidence of bilateral abnormalities in patients with unilateral symptoms lead us to conclude that HHS occurs when persons with preexisting palmar ulnar artery fibrodysplasia experience repetitive palmar trauma. This revised theory for the etiology of HHS explains why HHS does not develop in most patients with repetitive palmar trauma. (J Vasc Surg 2000;31:104-13.

Plasma Magnetohydrodynamics and Energy Conversion

Contains reports on four research projects.U. S. Air Force (Research and Technology Division) under Contract AF33(615)-1083 with the Air Force Aero Propulsion Laboratory, Wright-Patterson Air Force Base, Ohi