Mean hemodynamic response amplitudes (left channel 3, indicated in black, left inferior frontal junction) with standard errors of the mean in the peak activation region during phonological fluency.

<p>Mean amplitudes were adjusted for the covariates age, sex, education and performance of mean amplitudes. Values are shown for a) individuals without, with one, or with two or more vascular burden factors, and b) for individuals without and with hypertension.</p

Standardized β-weights of the predictor age in multiple regression analyses of hemodynamic responses in the replication sample of 727 individuals (a/b) and the initial sample (c/d; n = 325).

<p>Channels with significant (FDR-corrected) prediction of hemodynamic responses by age during (a) phonological fluency, and (b) semantic fluency. Regression models included the predictors age, sex, years of education and task performance.</p

Standardized β-weights of the predictor age in channel-wise (FDR-corrected) multiple regression analyses of hemodynamic response amplitudes during phonological fluency in a) individuals without hypertension, and b) individuals with hypertension.

<p>Regression models included the predictors age, sex, years of education and task performance. Interaction analyses of factor age and hypertension were not significant.</p