Ureteropelvic junction obstruction caused by metastatic cholangiocarcinoma

We describe the rare case of a 61-year-old female with right ureteropelvic junction (UPJ) obstruction caused by metastatic cholangiocarcinoma. Her past medical history was notable for cholangiocarcinoma treated with neoadjuvant chemoradiation and two orthotopic liver transplants six years earlier. Urology was consulted when she presented with flank pain and urinary tract infection. Diagnostic workup demonstrated right UPJ obstruction. She was managed acutely with percutaneous nephrostomy. She subsequently underwent robotic pyeloplasty and intrinsic obstruction of the UPJ was discovered. Histological examination revealed adenocarcinoma, consistent with systemic recurrence of the patient\u27s known cholangiocarcinoma

A molecular superfluid: non-classical rotations in doped para-hydrogen clusters

Clusters of para-hydrogen (pH2) have been predicted to exhibit superfluid behavior, but direct observation of this phenomenon has been elusive. Combining experiments and theoretical simulations, we have determined the size evolution of the superfluid response of pH2 clusters doped with carbon dioxide (CO2). Reduction of the effective inertia is observed when the dopant is surrounded by the pH2 solvent. This marks the onset of molecular superfluidity in pH2. The fractional occupation of solvation rings around CO2 correlates with enhanced superfluid response for certain cluster sizes

Package Deal: The Economic Impacts of Recycling Standards for Packaging in Massachusetts

The Island Foundation, The Jessie B. Cox Charitable Trust, The Charles Stuart Mott Foundation, The New England Biolabs Foundation, Haymarket People's Fund, The Jewish Communal Fund of New Yor

Spreading in Social Systems: Reflections

In this final chapter, we consider the state-of-the-art for spreading in social systems and discuss the future of the field. As part of this reflection, we identify a set of key challenges ahead. The challenges include the following questions: how can we improve the quality, quantity, extent, and accessibility of datasets? How can we extract more information from limited datasets? How can we take individual cognition and decision making processes into account? How can we incorporate other complexity of the real contagion processes? Finally, how can we translate research into positive real-world impact? In the following, we provide more context for each of these open questions.Comment: 7 pages, chapter to appear in "Spreading Dynamics in Social Systems"; Eds. Sune Lehmann and Yong-Yeol Ahn, Springer Natur

Synthesis and Characterization of 3,5-Bis(di-tert-butylphosphinito)pyridine Pincer Complexes

The synthesis of some “reverse pyridine” bis(phosphinite) pincer complexes of nickel and rhodium is reported. N-Functionalization of a POCOP ligand with a borane Lewis acid was found to permit cyclometalation with metal precursors, which reacted with the free base ligand in an undesired manner. Convenient removal of the coordinated Lewis acid was accomplished using polymer-supported 4-dimethylaminopyridine. The effects of borane Lewis acid coordination on the physical and spectroscopic properties of the pincer complexes were also assessed

Synthesis and Characterization of 3,5-Bis(di-tert-butylphosphinito)pyridine Pincer Complexes

The synthesis of some “reverse pyridine” bis(phosphinite) pincer complexes of nickel and rhodium is reported. N-Functionalization of a POCOP ligand with a borane Lewis acid was found to permit cyclometalation with metal precursors, which reacted with the free base ligand in an undesired manner. Convenient removal of the coordinated Lewis acid was accomplished using polymer-supported 4-dimethylaminopyridine. The effects of borane Lewis acid coordination on the physical and spectroscopic properties of the pincer complexes were also assessed