12 research outputs found
Evolution of a beam dynamics model for the transport lines in a proton therapy facility
Despite the fact that the first-order beam dynamics models allow an
approximated evaluation of the beam properties, their contribution is essential
during the conceptual design of an accelerator or beamline. However, during the
commissioning some of their limitations appear in the comparison against
measurements. The extension of the linear model to higher order effects is,
therefore, demanded. In this paper, the effects of particle-matter interaction
have been included in the model of the transport lines in the proton therapy
facility at the Paul Scherrer Institut (PSI) in Switzerland. To improve the
performance of the facility, a more precise model was required and has been
developed with the multi-particle open source beam dynamics code called OPAL
(Object oriented Particle Accelerator Library). In OPAL, the Monte Carlo
simulations of Coulomb scattering and energy loss are performed seamless with
the particle tracking. Beside the linear optics, the influence of the passive
elements (e.g. degrader, collimators, scattering foils and air gaps) on the
beam emittance and energy spread can be analysed in the new model. This allows
for a significantly improved precision in the prediction of beam transmission
and beam properties. The accuracy of the OPAL model has been confirmed by
numerous measurements.Comment: 17 pages, 19 figure
Full Scale Proton Beam Impact Testing of new CERN Collimators and Validation of a Numerical Approach for Future Operation
New collimators are being produced at CERN in the framework of a large
particle accelerator upgrade project to protect beam lines against stray
particles. Their movable jaws hold low density absorbers with tight geometric
requirements, while being able to withstand direct proton beam impacts. Such
events induce considerable thermo-mechanical loads, leading to complex
structural responses, which make the numerical analysis challenging. Hence, an
experiment has been developed to validate the jaw design under representative
conditions and to acquire online results to enhance the numerical models. Two
jaws have been impacted by high-intensity proton beams in a dedicated facility
at CERN and have recreated the worst possible scenario in future operation. The
analysis of online results coupled to post-irradiation examinations have
demonstrated that the jaw response remains in the elastic domain. However, they
have also highlighted how sensitive the jaw geometry is to its mounting support
inside the collimator. Proton beam impacts, as well as handling activities, may
alter the jaw flatness tolerance value by 70 m, whereas the
flatness tolerance requirement is 200 m. In spite of having validated
the jaw design for this application, the study points out numerical limitations
caused by the difficulties in describing complex geometries and boundary
conditions with such unprecedented requirements.Comment: 22 pages, 17 figures, Prepared for submission to JINS
Uncertainty quantification analysis and optimization for proton therapy beam lines
Since many years proton therapy is an effective treatment solution against deep-seated tumors. A precise quantification of sources of uncertainty in each proton therapy aspect (e.g. accelerator, beam lines, patient positioning, treatment planning) is of profound importance to increase the accuracy of the dose delivered to the patient. Together with Monte Carlo techniques, a new research field called Uncertainty Quantification (UQ) has been recently introduced to verify the robustness of the treatment planning. In this work we present the first application of UQ as a method to identify typical errors in the transport lines of a cyclotron-based proton therapy facility and analyze their impact on the properties of the therapeutic beams. We also demonstrate the potential of UQ methods in developing optimized beam optics solutions for high-dimensional problems. Sensitivity analysis and surrogate models offer a fast way to exclude unimportant parameters frcomplex optimization problems such as the design of a superconducting gantry performed at Paul Scherrer Institute in Switzerland
Cyclinac Medical Accelerators Using Pulsed C 6+ /H 2 + Ion Sources
ABSTRACT: Charged particle therapy, or so-called hadrontherapy, is developing very rapidly. There is large pressure on the scientific community to deliver dedicated accelerators, providing the best possible treatment modalities at the lowest cost. In this context, the Italian research Foundation TERA is developing fast-cycling accelerators, dubbed 'cyclinacs'. These are a combination of a cyclotron (accelerating ions to a fixed initial energy) followed by a high gradient linac boosting the ions energy up to the maximum needed for medical therapy. The linac is powered by many independently controlled klystrons to vary the beam energy from one pulse to the next. This accelerator is best suited to treat moving organs with a 4D multi-painting spot scanning technique. A dual proton/carbon ion cyclinac is here presented. It consists of an Electron Beam Ion Source, a superconducting isochronous cyclotron and a high-gradient linac. All these machines are pulsed at high repetition rate (100-400 Hz). The source should deliver both C 6+ and H 2 + ions in short pulses (1.5 ÎĽs flat-top) and with sufficient intensity (at least 10 8 fully stripped carbon ions at 300 Hz). The cyclotron accelerates the ions to 120 MeV/u. It features a compact design (with superconducting coils) and a low power consumption. The linac has a novel C-band high gradient structure and accelerates the ions to variable energies up to 400 MeV/u. High RF frequencies lead to power consumptions which are much lower than the ones of synchrotrons for the same ion extraction energy. This work is part of a collaboration with the CLIC group, which is working at CERN on highgradient electron-positron colliders
Cyclinac medical accelerators using pulsed C6+/H2+ ion sources
20 páginas, 9 figuras, 2 tablas.-- Trabajo presentado al International Symposium on Electron Beam Ion Sources and Traps (EBIST2010), celebrado en Estocolmo (Suecia/ Abril 2010).-- This work is part of a collaboration with the CLIC group, which is working at CERN on high-gradient electron-positron colliders.-- El PDF es la versión pre-print.-- et al.Charged particle therapy, or so-called hadrontherapy, is developing very rapidly. There is large pressure on the scientific community to deliver dedicated accelerators, providing the best possible treatment modalities at the lowest cost. In this context, the Italian research Foundation TERA is developing fast-cycling accelerators, dubbed `cyclinacs'. These are a combination of a cyclotron (accelerating ions to a fixed initial energy) followed by a high gradient linac boosting the ions energy up to the maximum needed for medical therapy. The linac is powered by many independently controlled klystrons to vary the beam energy from one pulse to the next. This accelerator is best suited to treat moving organs with a 4D multipainting spot scanning technique. A dual proton/carbon ion cyclinac is here presented. It consists of an Electron Beam Ion Source, a superconducting isochronous cyclotron and a high-gradient linac. All these machines are pulsed at high repetition rate (100–400 Hz). The source should deliver both C6+ and H2+ ions in short pulses (1.5 μs flat-top) and with sufficient intensity (at least 108 fully stripped carbon ions per pulse at 300 Hz). The cyclotron accelerates the ions to 120 MeV/u. It features a compact design (with superconducting coils) and a low power consumption. The linac has a novel C-band high-gradient structure and accelerates the ions to variable energies up to 400 MeV/u. High RF frequencies lead to power consumptions which are much lower than the ones of synchrotrons for the same ion extraction energy. This work is part of a collaboration with the CLIC group, which is working at CERN on high-gradient electron-positron colliders.The authors warmly thank A.D.A.M. S.A. and the Vodafone Foundation for their
generous financial support of TERA research activities.Peer reviewe
Full Scale Proton Beam Impact Testing of new CERN Collimators and Validation of a Numerical Approach for Future Operation
New collimators are being produced at CERN in the framework of a large particle accelerator upgrade project to protect beam lines against stray particles. Their movable jaws hold low density absorbers with tight geometric requirements, while being able to withstand direct proton beam impacts. Such events induce considerable thermo-mechanical loads, leading to complex structural responses, which make the numerical analysis challenging. Hence, an experiment has been developed to validate the jaw design under representative conditions and to acquire online results to enhance the numerical models. Two jaws have been impacted by high-intensity proton beams in a dedicated facility at CERN and have recreated the worst possible scenario in future operation. The analysis of online results coupled to post-irradiation examinations have demonstrated that the jaw response remains in the elastic domain. However, they have also highlighted how sensitive the jaw geometry is to its mounting support inside the collimator. Proton beam impacts, as well as handling activities, may alter the jaw flatness tolerance value by 70 m, whereas the flatness tolerance requirement is 200 m. In spite of having validated the jaw design for this application, the study points out numerical limitations caused by the difficulties in describing complex geometries and boundary conditions with such unprecedented requirements
Commissioning of a gantry beamline with rotator at a synchrotron-based ion therapy center
This paper provides an overview of the worldwide first commissioning of a gantry beamline with a rotator at the MedAustron synchrotron-based proton/ion cancer therapy facility in Wiener Neustadt, Austria. The gantry beamline consists of the high energy beam transfer (HEBT) line and the gantry beam transport system. It transports the beam from the synchrotron to the gantry-room isocenter. The HEBT transports the beam from the synchrotron to the gantry entrance, which is the coupling point between the HEBT and the gantry. The rotator is one of the HEBT modules, thus it is an integral part of the gantry beamline. The MedAustron rotator is the worldwide first rotator system used to match slowly extracted asymmetric beams from the synchrotron to the rotating gantry. In this paper, main attention is paid to ion-optical and beam-alignment aspects of the beamline commissioning. A novel orbit-correction and beam-alignment technique has been developed specifically for the beamline with the rotator. While the theoretical concept of the rotator has existed for almost two decades, the MedAustron rotator is the first hardware implementation of this concept all over the world. The presented overview of the beamline commissioning includes a description of the principal technical solutions and main results of the first beam-transport measurements. Since the measured beam size and beam position agree well with theoretical predictions, one can conclude that the proof-of-concept of the rotator-matching has been successfully accomplished