Aportaciones de la prospección geofísica al estudio del subsuelo del Berguedà y Solsonés. (pre-Pirineo Catalán, N.E. de la Península Ibérica)

A combined gravity and seismic study of a sector located in the limit of the Pre-Pyrenees and Catalonian Central Depresión structural units is presented. Two sets of geophysical data are used: gravity and seismic reflection, which are complementary since one detects subhorizontal limits while the other serves to locate heterogeneous density masses. To emphasize the local gravity anomalies, a residual map was obtained by removing the regional field, which is best represented by a second order trend surface. The most prominent features of this map are the gravity lows aligned over anticline structures. Gravity modelling constrained by seismic reflexion data reveals the existence of a low density plastic marls tectonically acumulated on the nucleus of the anticlines

Modelización gravimétrica 2D de la fosa de l'Empordà (NE de la Península Ibérica)

A gravimetric study of the Empordà Basin has been developed in this paper. Seismic reflection profiles and boreholes have furnished valuable data in order to build gravity models. The aim of this paper is the 2D modelling of the Empordà basin, and the calculation of neogene sediment thickness. 2D gravity profiles have been calculated parallel to the principal seismic lines

Tool-path effect on the geometric deviations in the machining of UNS A92024 aeronautic skins

Traditionally, aeronautics skins are being machined by chemical milling, a high-pollutant process. An efficient alternative to this technology is conventional machining. However, to ensure the parts machined with this process keeps the industrial quality controls, the effect of tool-path might be characterized, specially analyzing final thickness and roughness. In this paper, five different tool-paths have been applied under the same machining parameters in the dry milling of Al-Cu UNS A92024 thin plates. Machining time, final thickness and roughness have been evaluated. Most roughness and thickness results are under the industrial quality limits stablished for this type of parts.This work has received financial support from Spanish Goverment (Project DPI2015-71448-R), TECNALIA Research & Innovation and the University of Cadiz (University training plan UCA/REC01VI/2016)

Geofísica ambiental: técnicas no destructivas para el reconocimiento de zonas contaminadas por vertidos

Industrial countries face the consequences of decades of inappropiate handling of hazardous waste. The dumping of al1 types of hazardous materials has been ongoing in most industrialised countries for hundreds of years. Large quantities of industrial and other waste material have been buried in landfill sites. A relatively large number of these lack reliable man-made or natural geological barriers and toxic fluids are scaping and polluting the groundwater. The problem is greatly aggravated when a soil covenng is placed over the waste and there is no information about the dumping practices used in the past. One of the first tasks in any remedial action is to delineate the physical extent of the sites and its encroachment into the surrounding area. Test borings and limited excavations are very valuable but the information obtained is not continuous and dheir destructive nature makes it possible that waste could inadvertently be released during the probing phase. In this regard, both borehole drilling and excavation are very dangerous to workers and the environment and expensive and tedious to conduct.Many of these problems may be alleviated by using a geophysical assisted system approach to determine where the pollutants will go in the subsurface, gain more complete understanding of site conditions and asses the optimal placement of exploration drills and monitonng wells. At hazardous waste sites, the main objectives must commonly include:- Determine the presence, location, distribution, depth and composition of possible buried wastes.- Determine the presence and extent of contaminant and leachate plumes within the unsaturated and saturated zones.- Characterise and asses the local (and regional) geohydrologic regime for groundwater flow paterns, recharge areas and localised permeable pathways

A genome-wide association study on liver stiffness changes during hepatitis c virus infection cure

Liver stiffness (LS) at sustained virological response (SVR) after direct-acting antivirals (DAA)-based therapy is a predictor of liver events in hepatitis C virus (HCV)-infected patients. The study aim was to identify genetic factors associated with LS changes from the moment of starting anti-HCV therapy to SVR. This prospective study included HCV-infected patients from the GEHEP 011 cohort who achieved SVR with DAA-based therapy, with LS pre-treatment ≥9.5 kPa and LS measurement available at SVR. Plink and Magma software were used to carry out genome-wide single-nucleotide polymorphism (SNP)-based and gene-based association analyses, respectively. The ShinyGO application was used for exploring enrichment in Gene Ontology (GO) categories for biological processes. Overall, 242 patients were included. Median (quartile 1, quartile 3) LS values at pre-treatment and at SVR were 16.8 (12, 28) kPa and 12.0 (8.5, 19.3) kPa, respectively. Thirty-five SNPs and three genes reached suggestive association with LS changes from the moment of starting anti HCV therapy to SVR. GO categories related to DNA packaging complex, DNA conformation change, chromosome organization and chromatin organization were significantly enriched. Our study reports possible genetic factors associated with LS changes during HCV-infection cure. In addition, our results suggest that processes related to DNA conformation are also involved in these changes