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    Histologic features of bone regenerated by means of negative pressure in the context of odontogenic keratocyst

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    Prop贸sito: El objetivo de la presente investigaci贸n es describir las caracter铆sticas histol贸gicas del hueso regenerado mediante presi贸n negativa (sugosteog茅nesis) en un grupo de pacientes con diagn贸stico de queratoquiste odontog茅nico (QO) sometidos a descompresi贸n activa y sugosteog茅nesis por distracci贸n (ADDS) en nuestra instituci贸n. Materiales y m茅todos: Los autores dise帽aron un estudio retrospectivo de serie de casos. La poblaci贸n incluy贸 pacientes con diagn贸stico histol贸gico de queratoquiste odontog茅nico en los que se realiz贸 descompresi贸n activa y sugosteog茅nesis por distracci贸n seguida de enucleaci贸n. Todos los pacientes fueron atendidos y seguidos desde julio de 2019 hasta enero de 2021. La investigaci贸n fue aprobada por la Junta de Revisi贸n Institucional, y observ贸 la Declaraci贸n de Helsinki sobre protocolo m茅dico. Las variables de este estudio incluyeron la edad, el sexo, la localizaci贸n anat贸mica (mand铆bula o maxilar) y las caracter铆sticas histol贸gicas del hueso regenerado mediante presi贸n negativa. Las caracter铆sticas histol贸gicas se definieron como consistentes o inconsistentes con hueso maduro viable. Resultados: Se consideraron las biopsias 贸seas de 6 pacientes. En total, el 83,33% de los pacientes eran varones y el 16,66% mujeres. El cien por cien de las muestras 贸seas sometidas a presi贸n negativa mostraban caracter铆sticas de hueso maduro viable. Conclusiones: En este estudio, las caracter铆sticas histol贸gicas del hueso sometido a presi贸n negativa demostraron las caracter铆sticas normales del hueso maduro normal. 2022, El/los autor/es, bajo licencia exclusiva de Springer-Verlag GmbH Alemania, parte de Springer Nature.Purpose: The objective of the present research is to describe the histologic features of the bone regenerated by means of negative pressure (sugosteogenesis) in a group of patients diagnosed with odontogenic keratocyst (OKC) who underwent active decompression and distraction sugosteogenesis (ADDS) at our institution. Materials and methods: The authors designed a retrospective case series study. The population included patients with a histologic diagnosis of odontogenic keratocyst in whom active decompression and distraction sugosteogenesis followed by enucleation was performed. All patients were seen and followed from July 2019 to January 2021. The investigation was approved by the Institutional Review Board, and it observed the Declaration of Helsinki on medical protocol. Variables of this study included age, gender, anatomic location (mandible or maxilla), and histologic characteristics of the bone regenerated by means of negative pressure. Histologic features were defined as being consistent or inconsistent with viable mature bone. Results: Bone biopsies of 6 patients were considered. In total, 83.33% of patients were males and 16.66% females. One hundred percent of the bone samples subjected to negative pressure showed features of viable mature bone. Conclusions: In this study, the histological features of the bone subjected to negative pressure demonstrated the normal characteristics of the mature, normal bone. 漏 2022, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature
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