105 research outputs found
Les énergies marines renouvelables: Les défis d’une filière industrielle émergente
National audienceThe Renewable Marine Energy (RME) is a challenge and an opportunity for the very next decades. For many years France has been delaying its involvement in this industrial area but is now aiming to install 6 GW of electrical power produced at sea by 2020. To keep in line with these international and European commitments, France encourages many stakeholders to join their efforts towards a fast and efficient development of these technologies within the French waters. This paper introduces the industrial background and the outstanding actions – from government and regional authorities. The Pôle Mer Bretagne (Brittany Maritime Competitiveness Cluster) is dealing with to help developing the RME industry in France. It is foreseen that this industry will represent by 2020 an overall market of 30 billion euros and 10 000 jobs. To achieve such a goal, several actions have been launched these last years. Among those, the best financial tool is the "Investment for the Future" ("Investissements d'avenir") initiative which offers a proper framework to develop ambitious projects such as:• The five R&D projects dedicated to the design of innovative offshore energy harnessing devices:- Two floating wind turbines (WINFLO & VERTIWIND)- Two tidal turbines (ORCA & SABELLA)- And one wave converter (S3)• The Institute of Excellence in Carbon-free Energy "France Energie Marine" aiming at aggregating all the French research efforts dedicated to RME and to manage the test sites that already exist or that will be installed soon.• The selection of the contractors for the four first French wind farms to be installed in the Channel and the Atlantic Ocean for a total power of 1 728 MW.The paper introduces the various devices to be designed in the next future, highlighting the critical aspects where R&D is still needed, and the specificities of such systems from an electrical engineering point of view. Finally it concludes with an overviewof the supporting initiatives, such as education and infrastructures, and of the perspectives
Recommendations on the use of recombinant activated factor VII as an adjunctive treatment for massive bleeding – a European perspective
INTRODUCTION: Our aim was to develop consensus guidelines for use of recombinant activated factor VII (rFVIIa) in massive hemorrhage. METHODS: A guidelines committee derived the recommendations using clinical trial and case series data identified through searches of available databases. Guidelines were graded on a scale of A to E (with A being the highest) according to the strength of evidence available. Consensus was sought among the committee members for each recommendation. RESULTS: A recommendation for the use of rFVIIa in blunt trauma was made (grade B). rFVIIa might also be beneficial in post-partum hemorrhage (grade E), uncontrolled bleeding in surgical patients (grade E), and bleeding after cardiac surgery (grade D). rFVIIa could not be recommended for use in the following: in penetrating trauma (grade B); prophylactically in elective surgery (grade A) or liver surgery (grade B); or in bleeding episodes in patients with Child–Pugh A cirrhosis (grade B). Efficacy of rFVIIa was considered uncertain in bleeding episodes in patients with Child–Pugh B and C cirrhosis (grade C). Monitoring of rFVIIa efficacy should be performed visually and by assessment of transfusion requirements (grade E), while thromboembolic adverse events are a cause for concern. rFVIIa should not be administered to patients considered unsalvageable by the treating medical team. CONCLUSION: There is a rationale for using rFVIIa to treat massive bleeding in certain indications, but only adjunctively to the surgical control of bleeding once conventional therapies have failed. Lack of data from randomized, controlled clinical trials, and possible publication bias of the case series data, limits the strength of the recommendations that can be made
Transcatheter tricuspid valve implantation: A multicentre French study
SummaryBackgroundTranscatheter valve-in-valve (VIV) implantation in failing bioprosthesis is an emerging field in cardiology.AimTo report on a French multicentre experience and a literature review of tricuspid VIV implantation.MethodsWe approached different institutions and collected 10 unpublished cases; a literature review identified 71 patients, including our 10 cases. Clinical aspects and haemodynamic data are discussed.ResultsAmong our 10 unpublished cases, the reason for implantation was significant tricuspid stenosis (n=4), significant tricuspid regurgitation (n=1) or mixed lesion (n=5). Implantation was performed under general anaesthesia at mean age 28±17 years. The 22mm Melody valve was implanted in seven patients; the Edwards SAPIEN valve was implanted in three patients. The procedure succeeded in all cases, despite two embolizations in the right cardiac chambers; in both cases, the valve was stabilized close to the tricuspid annulus using a self-expandable stent, before implantation of a second Edwards SAPIEN valve. Functional class improved in all but one case. Mean diastolic gradient decreased from 9±2.45mmHg to 3.65±0.7mmHg (p=0.007); no more than trivial regurgitation was noticed. Among the published cases, the Melody valve was implanted in 41 patients, the Edwards SAPIEN valve in 29 patients and the Braile valve in one patient. Short-term results were similar for our 10 cases, but mid-term results are not yet available.ConclusionsTricuspid VIV implantation using the Melody or Edwards SAPIEN valves is a feasible and effective procedure for selected patients with failing bioprosthesis
les énergies marines renouvelables: Les défis d’une filière industrielle émergente
The Renewable Marine Energy (RME) is a challenge and an opportunity for the very next decades. For many years France has been delaying its involvement in this industrial area but is now aiming to install 6 GW of electrical power produced at sea by 2020. To keep in line with these international and European commitments, France encourages many stakeholders to join their efforts towards a fast and efficient development of these technologies within the French waters. This paper introduces the industrial background and the outstanding actions – from government and regional authorities. The Pôle Mer Bretagne (Brittany Maritime Competitiveness Cluster) is dealing with to help developing the RME industry in France. It is foreseen that this industry will represent by 2020 an overall market of 30 billion euros and 10 000 jobs. To achieve such a goal, several actions have been launched these last years. Among those, the best financial tool is the "Investment for the Future" ("Investissements d'avenir") initiative which offers a proper framework to develop ambitious projects such as: • The five R&D projects dedicated to the design of innovative offshore energy harnessing devices: - Two floating wind turbines (WINFLO & VERTIWIND) - Two tidal turbines (ORCA & SABELLA) - And one wave converter (S3) • The Institute of Excellence in Carbon-free Energy "France Energie Marine" aiming at aggregating all the French research efforts dedicated to RME and to manage the test sites that already exist or that will be installed soon. • The selection of the contractors for the four first French wind farms to be installed in the Channel and the Atlantic Ocean for a total power of 1 728 MW. The paper introduces the various devices to be designed in the next future, highlighting the critical aspects where R&D is still needed, and the specificities of such systems from an electrical engineering point of view. Finally it concludes with an overview of the supporting initiatives, such as education and infrastructures, and of the perspectives
Les régions «sans meubles» : le cas du Poitou-Charentes (en particulier des diocèses de Poitiers et La Rochelle)
Riou Yves-Jean. Les régions «sans meubles» : le cas du Poitou-Charentes (en particulier des diocèses de Poitiers et La Rochelle). In: Revue de l'Art, 1986, n°71. pp. 71-76
Premesse per un repertorio sistematico delle opère e degli artisti della Valle Intelvi. Atti del convegno internazionale... promosso dalla « Magistri intelvesi ». Villa Monastero di Varenna, 1-4 settembre 1966. Dir. Maria- Luisa Gatti Perer
Riou Yves-Jean. Premesse per un repertorio sistematico delle opère e degli artisti della Valle Intelvi. Atti del convegno internazionale... promosso dalla « Magistri intelvesi ». Villa Monastero di Varenna, 1-4 settembre 1966. Dir. Maria- Luisa Gatti Perer. In: Cahiers de civilisation médiévale, 11e année (n°42), Avril-juin 1968. p. 248
L’album de dessins de François Thiollet : une source architecturale et topographique post révolutionnaire
Riou Yves-Jean. L’album de dessins de François Thiollet : une source architecturale et topographique post révolutionnaire. In: Bulletin Monumental, tome 175, n°1, année 2017. p. 71
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