Additional file 1: of A scoping review of palliative care for children in low- and middle-income countries

The discription of the search strategy. (DOCX 20 kb

Adjusted odds ratios (ORs) for adverse maternal and perinatal outcomes of pre-eclampsia.

<p>Adjusted for facility capacity index score at facility level, GNI per capita and maternal mortality ratio at the country level, marital status, maternal education, maternal age, maternal BMI, parity, clinical conditions (hypertension, diabetes, cardiac/renal disease, pyelonephritis or urinary infection, severe anemia) and number of antenatal care visits at the individual level.</p>a<p>Also adjusted for infant sex.</p>b<p>Also adjusted for gestational age.</p

Pre-eclampsia prevalence per facility by country and region.

<p>Plot showing prevalence of pre-eclampsia per facility by country and region (Africa, Asia and Latin America).</p

Distribution of pre-eclampsia and its adverse maternal and perinatal outcomes in the study population by region and country.

<p>*Democratic Republic of Congo; NR- not reported.</p

Adjusted odds ratios (ORs) of risk factors for pre-eclampsia/eclampsia.

<p>Three-level structure logistic random effects regression models were used to obtain the Adjusted ORs: individual (level 1); facility (level 2); and country (level 3) adjusted with variables in the table.</p

Overall and regional distribution of risk factors for pre-eclampsia/eclampsia.

<p>Overall and regional distribution of risk factors for pre-eclampsia/eclampsia.</p

Estimation of cases detected and cases intervened by different screening strategies.

<p>Estimation of cases detected and cases intervened by different screening strategies.</p

Additional file 2: of Assessing health-related quality of life in Japanese children with a chronic condition: validation of the DISABKIDS chronic generic module

Summary of Confirmatory Factor Analysis. (PDF 10 kb

Cost-Effectiveness Analysis of a National Neonatal Hearing Screening Program in China: Conditions for the Scale-Up

<div><h3>Background</h3><p>In 2009, the Chinese Ministry of Health recommended scale-up of routine neonatal hearing screening - previously performed primarily only in select urban hospitals - throughout the entire country.</p> <h3>Methods</h3><p>A decision analytical model for a simulated population of all live births in China was developed to compare the costs and health effects of five mutually exclusive interventions: 1) universal screening using Otoacoustic Emission (OAE) and Automated Auditory Brainstem Response (AABR); 2) universal OAE; 3) targeted OAE and AABR; 4) targeted OAE; and 5) no screening. Disability-Adjusted Life Years (DALYs) were calculated for health effects.</p> <h3>Results and Discussion</h3><p>Based on the cost-effectiveness and potential health outcomes, the optimal path for scale-up would be to start with targeted OAE and then expand to universal OAE and universal OAE plus AABR. Accessibility of screening, diagnosis, and intervention services significantly affect decision of the options.</p> <h3>Conclusion</h3><p>In conclusion, to achieve cost-effectiveness and best health outcomes of the NHS program, the accessibility of screening, diagnosis, and intervention services should be expanded to reach a larger population. The results are thus expected to be of particular benefit in terms of the ‘rolling out’ of the national plan.</p> </div

Decision tree for cost-effectiveness analysis of different screening strategies among all simulated live births in China.

<p>Decision tree for cost-effectiveness analysis of different screening strategies among all simulated live births in China.</p