Peranan Ultraviolet B Sinar Matahari terhadap Status Vitamin D dan Tekanan Darah pada Wanita Usia Subur

Sinar ultraviolet B adalah sumber utama vitamin D, tetapi wanita usia subur yang bekerja di dalam ruangan mempunyai vitamin D yang rendah meskipun Indonesia negara tropis. Tujuan penelitian ini untuk mengevaluasi peranan paparan sinar matahari pada wanita usia subur terhadap status vitamin D dan tekanan darah. Desain penelitian yang digunakan adalah eksperimen tanpa kelompok kontrol pada 21 wanita sehat. Penelitian ini membandingkan status vitamin D dan tekanan darah sebelum dan setelah mendapat paparan sinar matahari pada wajah dan lengan tiga kali seminggu selama 12 minggu. Analisis data menggunakan uji t-berpasangan. Paparan sinar matahari dapat meningkatkan vitamin D. Serum 25(OH)D meningkat 15,9% dari 15.7 ng/dL menjadi 18,2 ng/dL. Paparan sinar matahari menurunkan tekanan darah sistolik (nilai p = 0,004) dan diastolik (nilai p = 0,011). Ultraviolet B dari sinar matahari 30 menit tiga kali seminggu selama 12 minggu dapat memperbaiki status vitamin D dan tekanan darah.Ultraviolet B sunlight exposure is a primary source of vitamin D, but women of childbearing age who worked in room every day had low serum vitamin D despite Indonesia is a tropical country. The objective of this study was to evaluate the role of sun exposure in women of childbearing age on vitamin D status, and blood pressure. An intervention before-after study without group control was conducted on 21 healthy women. This study compared vitamin D status, and blood pressure before and after receiving ultraviolet B (UVB) from sun exposure on the face and both arms three times a week for 12 weeks. Anthropometric parameter and blood pressure were measured, were determined at baseline and after 12 weeks of sun exposure. The effect of sun exposure can improve vitamin D. Serum 25 (OH)D increase 15.9% from 15.7 ng/dL to 18.2 ng/dL. Sun exposure significantly reduced systolic blood pressure (p value = 0.004), and diastolic blood pressure (p value = 0.011). Ultraviolet B from sun exposure for 30 minutes, 3 times a week for 12 weeks improves the vitamin D status, and blood pressure

Pengaruh Pemberian Suplemen Selenium Dan Iodium Terhadap Status Gizi, Skor IQ Dan Jumlah Tanda Khas Kretin Pada Anak Sekolah Dasar

Iodine Deficiency Disorder (IDD) and Protein Energy Malnutrition (PEM) is still a public health problem in school-aged children living in endemic area. This study was aimed to investigate some biochemical parameters, nutritional status and IQ score in children in endemic area of Boyolali Regency, Central Java. Before and after quasi experimental study design was implemented. A number of 115 school-aged children (9-12 years) with iodine deficiency, PEM problem and attributed to 6-10 sign of cretinism were selected as study sample. Sampling was conducted by using random sampling procedure. The Group of treatment were selenium supplement (n=34), iodine supplement (n=35), selenium and iodine (n=18) and placebo (n=28). The study found that selenium, iodine, selenium and iodine supplement intervention were significantly reduce the stunted (p=0.04, r=0.587) and underweight (p=0.01, r=0.87). Selenium and iodine were able to improved IQ score of those who were deficient with IQ score under 20 (14.8% student) to IQ score 20-35. The children with very severe deficiency of iodine and selenium (17.4%) and IQ score under 20 could be corrected by iodine supplement and IQ score increased to 20-35. A reduction of the cretinism attributes were found among the children after intervention (from 6-11 sign to 5-10 sign). Anomaly of erythrocytes and leucocytes were found to be associated with severity of stunted and underweight, number of attributes and deficiency level of selenium and iodine

Penilaian Kromium Serum Darah pada Penyandang Diabetes Mellitus Tipe 2 dan Non Diabetes

Diabetes mellitus tipe 2 merupakan salah satu masalah kesehatan dunia. Berdasarkan survei Riskesdas 2013, prevalensi dari diabetes melitus tipe 2 di Indonesia pada usia 15 tahun atau lebih adalah 6.9%. Prevalensiyang tinggi dapat dipicu oleh diet yang kurang sehat dan rendahnya aktivitas fisik. Kromium dalam hal ini sebagai mineral mikro yang memiliki peran dalam menjaga homeostasis glukosa darah diduga memiliki fungsi dalam meningkatkan respon insulin. Penelitan ini bertujuan mengetahui hubungan antara aktivitas fisik, tingkat kecukupan energi dan zat gizi, dengan kadar glukosa darah puasa dan HbA1c. Desain penelitian ini adalah survei potong lintang dengan subjek penyandang diabetes tipe 2 sebanyak 42 orang dan subjek normal sebanyak 49 orang. Kriteria inklusi adalah pria atau wanita normal atau penyandang diabetes usia 50-65 tahun, sudah menopause untuk wanita minimal 1 tahun, dan bersedia mengikuti penelitian dengan menandatangani informed concent. Hasil penelitian menunjukkan bahwa Cr serum darah pada penyandang diabetes lebih rendah dibandingkan pada subjek normal. Terdapat hubungan yang signifikan antara HbA1c dengan IMT, lingkar pinggang, aktivitas fisik, Cr serum darah, dan tingkat kecukupan serat. Tingkat kecukupan Cr berpengaruh signifikan terhadap HbA1c. Tingkat Cr serum HbA1C (r = -0.466, p<0.01). kesimpulan dari penelitian ini adalah rendahnya tingkat Cr serum darah diduga menjadi salah satu penyebab berkembangnya diabetes mellitus tipe 2

Efek Diet Tinggi Kolesterol Terhadap Peningkatan Kolesterol Darah, Gambaran Histopatologi Hati, Dan Bobot Badan Kelinci New Zealand White Jantan

This study was conducted to analyze the high cholesterol diet effect of egg yolk powder toward the increase of blood cholesterol and body weight in male New Zealand White rabbit and learned their liver histophatology figure. The experimental studies with Completely Randomized Design (CRD) used 13 male New Zealand White rabbit aged 6 – 7 months and weight 2,9 – 4,0 kg. Rabbit were divided into 3 groups: group 0 (n=4) given the standard feed, group 1 (n=4) given high cholesterol diet from egg yolk powder, and group 2 (n=5) given high cholesterol diet from egg yolk powder and red palm oil mix. The intervention was implemented for 8 weeks after 4 weeks adaptation period. The results showed that intervention of high cholesterol diet from egg yolk powder significantly increased levels of serum cholesterol and fatty liver, but did not significantly affect body weight of male New Zealand White rabbit

Food and Zinc Intake, and Determinant of Zinc Status Among Pregnant Women in Leuwiliang and Cibungbulang Sub-Districts, District of Bogor

The objectives of this study were to analyze zinc status, nutrient dietary quality, zinc content, zinc intake, determinant of zinc status and implications for preventing zinc deficiency among pregnant women living in Leuwiliang and Cibungbulang sub-districts, district of Bogor. The research used base line data of 252 pregnant women from previous study entitled "Effect of Multi-nutrients Fortificated Food Supplement for Pregnant Women and Child Growth and Development in Leuwiliang and Cibungbulang". Additional data collected were local food potency, zinc content of 17 foods, and formal and nonformal local leaders opinion on future institution programs related to nutrition and health.Logistic regression was applied for determinants analysis

Pengaruh Pengolahan Kedelai Menjadi Tempe Dan Pemasakan Tempe Terhadap Kadar Isoflavon (Effects of Soybean Processing Becoming Tempeh and the Cooking of Tempeh on Isoflavones Level)

Background: Research over the past two decades has provided significant clinical trial and epidemiological evidence for health benefits of the consumption of soybean-based foods. A health claim indicating that high soybean consumption is associated with a lower risk of coronary heart disease (CHD). Compositions of nutrient and non-nutrient in soybean have been examination and give the contribution on lower risk of CHD especially on improve of lipid profile. Isoflavones is a non-nutrient that abundant in soybean. Tempeh is fermented soybean that popular as Indonesian traditional food and content of isoflavones is greater than soybean. Objective: to study effect of soybean processing becoming tempeh and the cooking of tempeh on isoflavones level. Methods: The samples of this study is raw tempeh and steamed tempeh. The analysis of isoflavones has used high performance liquid chromatography (HPLC). Results: During soybean processing becoming tempeh, twice boiling of soybean produce result isoflavones 47.4 percent greater than once boiling. Steaming tempeh result minimized isoflavones reduction (13.3%). Although there is no dietary recommendation for individual isoflavones, may be great benefit in increased consumption of tempeh. [Penel Gizi Makan 2010, 33(2): 148-153

Potensi Asam Amino pada Tempe untuk Memperbaiki Profil Lipid dan Diabetes Mellitus

Degenerative diseases prevalence had been arining over years. One of the causes is the life style changes including eating pattern. Tempeh, an Indonesian soybean traditionally fermented food, was known and consumed by almost all Indonesian people. However, only a few know the health benefit of tempeh. Tempeh was also welknown and cheap protein source food affordable for the poor. Hence, there is a need to explore the nutritious content of tempeh and health benefit of it deeper such as in preventing degenerative diseases. Fermentation process of soybean to becometempeh had improved nutrient and non-nutrient contents that make tempeh better than soybean. Tempeh protein is more digestible than soybean and the arginine content increases twice, that could improve lipid profile and diabetes mellitus. Tempeh could be considered as functional food having health benefit

Efek Pemberian Gula Kelapa yang Diperkaya Minyak Sawit Merah terhadap Peningkatan Berat Badan dan Kadar Retinol Serum Tikus Defisien Vitamin A (Effect Of The Feeding Of Brown Sugar Enriched With Red Palm Oil On Body Weight Gain And Serum Retinol Levels

Vitamin A deficiency (VAD) is an important cause of blindness and premature death. Vitamin A also plays an important role on growth and immune function. Red palm oil is the richest naturally occurring source of β-carotene, a carotenoid that the human body can convert into USAble vitamin A (retinol). This research was to evaluate the effect of feeding red palm oil enriched brown sugar on improving body weight and serum retinol level of vitamin A depletion Sprague-Dawley rats. Twenty four of six weeks old-male Sprague Dawley rats were used. After 2 weeks of adaptation period, rats were given vitamin A deficient diet (modified AIN-93M) for 10 weeks, and then divided into 3 groups and received for 2 weeks the different treatment as repletion period: 1) RPO group which received red palm oil enriched brown sugar (1.5 mL/d), 2) CPO group which received crude palm oil enriched brown sugar (1.5 mL/d) and 3) and RE group which received retinyl palmitate (0.6 mL/d) . Each treatment contains approximately 40 µg beta carotene/day. Intervention by feeding brown sugar enriched with RPO and CPO for 2 weeks can increase the body weight of rats by 3.54 percent and 5.23 percent, respectively, which is markedly better than the group that was given retynil palmitat (9.38%) (p&lt;0.05). However, an increase in serum retinol concentrations in all group showed no significant differences (p&gt;0.05). Consumption of brown sugar enriched with RPO or CPO enhances body weight and serum retinol concentration of vitamin A deficient rats