Autumn microhabitat breadth differs between family groups of Atlantic salmon parr (Salmo salar) in a small chalk stream

The effect of family traits on the microhabitat use by six genetically distinct groups (three in each year of study) of juvenile Atlantic salmon tagged with passive integrated transponder (PIT) tags was studied via PIT-tag detectors installed on the river bed in a small chalk stream of southern England, during Autumn in 2006 and 2007. Canonical correspondence analysis of the molecular and microhabitat data revealed considerable overlap in the microhabitat use of the family groups and notable differences in microhabitat breadth, which was partly influenced by sample size. The data suggest that microhabitat breadth and preferences of wild salmon are influenced by family of origin

Minimal breast milk transfer of rituximab, a monoclonal antibody used in neurological conditions.

ObjectiveTo determine the transfer of rituximab, an anti-CD20 monoclonal antibody widely used for neurologic conditions, into mature breast milk.MethodsBreast milk samples were collected from 9 women with MS who received rituximab 500 or 1,000 mg intravenous once or twice while breastfeeding from November 2017 to April 2019. Serial breast milk samples were collected before infusion and at 8 hours, 24 hours, 7 days, and 18-21 days after rituximab infusion in 4 patients. Five additional patients provided 1-2 samples at various times after rituximab infusion.ResultsThe median average rituximab concentration in mature breast milk was low at 0.063 μg/mL (range 0.046-0.097) in the 4 patients with serial breast milk collection, with an estimated median absolute infant dose of 0.0094 mg/kg/d and a relative infant dose (RID) of 0.08% (range 0.06%-0.10%). Most patients had a maximum concentration at 1-7 days after infusion. The maximum concentration occurred in a woman with a single breast milk sample and was 0.29 μg/mL at 11 days postinfusion, which corresponds with an estimated RID of 0.33%. Rituximab concentration in milk was virtually undetectable by 90 days postinfusion.ConclusionsWe determined minimal transfer of rituximab into mature breast milk. The RID for rituximab was less than 0.4% and well below theoretically acceptable levels of less than 10%. Low oral bioavailability would probably also limit the absorption of rituximab by the newborn. In women with serious autoimmune neurologic conditions, monoclonal antibody therapy may afford an acceptable benefit to risk ratio, supporting both maternal treatment and breastfeeding

Tax Levy Financing for Local Public Health: Relationships between Fiscal Allocation, Fiscal Effort and Fiscal Capacity

This study examines property tax levy (local tax levy) as a source of local health department (LHD) funding during a five year period (2006-2010) in all Minnesota counties by assessing fiscal effort, fiscal allocation and fiscal capacity. Local health departments rely on pluralistic funding from local, state, federal and private sources. However, local tax levy funding is unexplored and little is known regarding the extent of fiscal allocation (tax levy used for LHD), fiscal effort (potential amount of tax levy available for LHD), and fiscal capacity (wealth of community). More important it is not known to what extent variation between local jurisdictions fluctuated over time, how they are offset by declining funding from other sources, or whether other sources supplement total tax levy reductions. It is essential to explore these issues to provide a basic understanding of fiscal drivers for ongoing services. Our findings indicate that from 2006 to 2010 the local tax levy for public health as a percent of total local health department expenditures decreased 6.7%, while local tax levy for public health as a percent of total tax levy decreased 14.6%. However, during this time period the total per capita tax levy for all services increased 25.2%

Connections: A Journal of Public Education Advocacy - Fall 2002, Vol. 9, No. 2

President's Message - Wendy D. Puriefoy sees education as the universal liberator and children as our nation's most valuable resource.Richard Riley on Transforming American Education - Don't shortchange adolescents, urges Richard W. Riley, Clinton administration secretary of education, as we build for a knowledge-driven economy.Q&A: Bob Moses - Civil rights activist Bob Moses promotes math literacy as the key to education and economic access.Making It Happen - Phyllis McClure, Title I expert, alerts parents and communities to valuable NCLB-mandated information on schools, districts, and states coming their way.Viewpoint - Boeing Company CEO Philip M. Condit links the need for a worldclass workforce to the need for quality public education.Conversations - Grassroots organizer Donna Cooper, Maryland lawmaker Pete Rawlings, and New York attorney Michael Rebell discuss accountability, adequacy, and fiscal equity as long-term investments in the future of our nation.End Notes - William Novelli, CEO, on how AARP members put lifelong learning into action

The impact of streetlights on an aquatic invasive species: artificial light at night alters signal crayfish behaviour

Artificial light at night (ALAN) can significantly alter the behaviour, communication and orientation of animals, and will potentially interact with other stressors to affect biodiversity. Invasive, non-native species are one of the largest threats to freshwater biodiversity; however, the impact of ALAN on such species is unknown. This study assessed the effects of ALAN at ecologically relevant levels on the behaviour of a globally widespread invasive species, the signal crayfish (Pacifastacus leniusculus). In experimental aquaria, crayfish were exposed to periods of daylight, control (<0.1 lx) and street-lit nights to test two hypotheses: (1) signal crayfish under natural conditions are nocturnal animals, spending more time in shelter during the day, whilst active and interacting during the night, and (2) ALAN reduces crayfish activity and intraspecific interactions, whilst increasing their propensity to use shelter. Our results confirm that signal crayfish are largely nocturnal, showing peak activity and interaction levels during control nights, whilst taking refuge during daylight hours. When exposed to short-term simulated light pollution from a streetlight at night however, activity and interactions with conspecifics were significantly reduced compared to control nights, whilst time spent in shelters increased. By altering crayfish behaviour, ALAN may change the ecosystem impacts of invasive crayfish in the wild. This study is the first to show an impact of ALAN on the behaviour of an invasive, non-native species, and provides information for the management of invasive crayfish in areas where ALAN is prevalent

Educational Services Center for Minority Students, Correspondence 1973

Correspondence between Adrienne Riley, Acting Director of Educational Services Center for Minority Students, Dr. Lloyd Luckmann, Dean of Colleges of Liberal Arts and Sciences, Dr. John Marshall, Vice President of Student Development, and William C. McInnes, S.J. President of USF. Includes pamphlet from program

Does relatedness influence migratory timing and behaviour in Atlantic salmon smolts?

Aggregating and moving with relatives may enable animals to increase opportunities for kin selection to occur. To gain group-living benefits, animals must coordinate their behaviour. Atlantic salmon, Salmo salar, demonstrate both territoriality and schooling: the two key social behaviours performed by fish. In this investigation we compared the migratory timing and behaviour of six distinct full-sibling groups of tagged S. salar smolts with a large control sample from the same wild population. The results clearly demonstrate that the incidence of schooling and diel migratory timing is not significantly influenced by relatedness, and this adds further support to the hypothesis that S. salar smolt migration is primarily an adaptive response to environmental conditions, rather than a behaviour based solely on genetics or kin-biased behaviour. Used in conjunction with the results of two previous investigations, this is the first study to illustrate that kin discrimination among full-sibling groups of parr does not lead to kin-biased schooling in smolts. Thus, even within the same full-sibling groups, the extent of kin-biased behaviour in fish can both differ within a life history stage under varying ecological conditions and shift from one life history stage to the next

Initial Laboratory-Scale Melter Test Results for Combined Fission Product Waste

This report describes the methods and results used to vitrify a baseline glass, CSLNTM-C-2.5 in support of the AFCI (Advanced Fuel Cycle Initiative) using a Quartz Crucible Scale Melter at the Pacific Northwest National Laboratory. Document number AFCI-WAST-PMO-MI-DV-2009-000184

Using novel methodologies to examine the impact of artificial light at night on the cortisol stress response in dispersing Atlantic salmon (Salmo salarL.) fry

Artificial light at night (ALAN) is gaining recognition as having an important anthropogenic impact on the environment, yet the behavioural and physiological impacts of this stressor are largely unknown. This dearth of information is particularly true for freshwater ecosystems, which are already heavily impacted by anthropogenic pressures. Atlantic salmon (Salmo salar L.) is a species of conservation and economic importance whose ecology and behaviour is well studied, making it an ideal model species. Recent investigations have demonstrated that salmon show disrupted behaviour in response to artificial light; however, it is not yet clear which physiological processes are behind the observed behavioural modifications. Here, two novel non-invasive sampling methods were used to examine the cortisol stress response of dispersing salmon fry under different artificial lighting intensities. Fish egg and embryos were reared under differing ALAN intensities and individual measures of stress were subsequently taken from dispersing fry using static sampling, whereas population-level measures were achieved using deployed passive samplers. Dispersing fry exposed to experimental confinement showed elevated cortisol levels, indicating the capacity to mount a stress response at this early stage in ontogenesis. However, only one of the two methods for sampling cortisol used in this study indicated that ALAN may act as a stressor to dispersing salmon fry. As such, a cortisol-mediated response to light was not strongly supported. Furthermore, the efficacy of the two non-invasive methodologies used in this study is, subject to further validation, indicative of them proving useful in future ecological studies

The impact of next and back buttons on time to complete and measurement reliability in computer-based surveys

To assess the impact of including next and back buttons on response burden and measurement reliability of computer-based surveys. A sample of 807 participants (mean age of 53; 64% women, 83% non-Hispanic white; 81% some college or college graduates) from the YouGov Polimetrix panel was administered 56 items assessing performance of social/role activities and 56 items measuring satisfaction with social/role activities. Participants were randomly assigned to either (1) automatic advance to the next question with no opportunity to go back (auto/no back); (2) automatic advance to the next questions with an opportunity to go back (auto/back); (3) next button to go to the next question with no opportunity to go back (next/no back); or (4) next button to go to the next question with an opportunity to go back (next/back). We found no difference in missing data, internal consistency reliability, and domain scores by group. Time to complete the survey was about 50% longer when respondents were required to use a next button to go on. Given the similarity in missing data, reliability and mean scale scores with or without use of the next button, we recommend automatic advancement to the next item with the option to go back to the previous item