Letter in Reply: Appendiceal Inflammatory Myofibroblastic Tumor and HIV Infection, An Association Not To Be Missed

We read with interest the comments made by Al-Mendalawi on our publication, and we thank him for his useful comments and suggestions

Primary leiomyosarcoma of the inferior vena cava: Report of a case diagnosed by fine needle aspiration cytology and confirmed by histopathologic examination

Leiomyosarcoma is a malignant neoplasm and can originate within major abdominal veins, including the inferior vena cava (IVC). Case A 45-year-old woman presented with upper abdominal pain and a mass lesion in the liver and within the lumen of the IVC. A diagnosis of primary leiomyosarcoma of the IVC was made by using imaging techniques, fine needle aspiration cytology and histopathologic examination of the resected specimen. Conclusion: In patients presenting with vague upper abdominal pain and radiologic features of a hepatic mass extending to major veins, the rare possibility of primary leiomyosarcoma of the IVC should be considered and investigated by both fine needle aspiration cytology and intraoperative histology. Early surgical intervention and/or postoperative chemotherapy and radiotherapy are associated with improved survival

UNUSUAL CLINICOPATHOLOGICAL AND IMMUNOLOGICAL PRESENTATION OF CHRONIC BULLOUS DERMATOSIS OF CHILDHOOD (LINEAR IGA DERMATOSIS)

Linear IgA bullous dermatosis is a rare sulfone-responsive subepidermal blistering disorder of unknown etiology in which smooth linear deposits of IgA are found in the basement membrane zone. Chronic bullous dermatosis of childhood is equivalent to linear IgA disease of adulthood and is characterized by an abrupt onset of large, widespread and tense bullae on a normal or erythematous base. In this case, we describe an unusual presentation of chronic bullous dermatosis in a 14-month-old Saudi girl. Histopathological examination revealed subepidermal cell poor blisters with linear deposition of IgA, IgG, IgM, and C3 along the dermoepidermal junction. The unusual clinical, histopathological and immunofluorescence findings in this patient are discussed, with an account on the differential diagnosis in such cases along with a detailed review of the relevant literature

Safety of intraneural injection of local anesthetic

There is conflicting information in the literature regarding nerve damage following regional anesthesia. Intraneural injection of local anesthetic was described as a safe practice in regional anesthesia. This review focuses on the histopathological and functional assessment of peripheral nerve function following intraneural injection of local anesthetics

Tuberculosis of the Tongue Clinically Masquerading as a Neoplasm: A Case Report and Literature Review

Tuberculosis of the tongue is a very rare event even in areas and countries in which tuberculosis is endemic. The disease can present itself in a variety of clinical appearances, most of which may mimic malignant lingual neoplasms clinically. In this case, we present a patient who initially complained of an ulcerated lingual swelling, which was suspected to be a squamous cell carcinoma on clinical examination. In addition, the diagnosis was missed on the first and initial biopsy as it was not representative of the lesion. The diagnosis of lingual tuberculosis was made by histopathology on a second biopsy. In this article, we described the clinicopathological features of tuberculous glossitis with a comparison between our case and other similar reported cases in addition to a literature review

Acrodermatitis Continua of Hallopeau with Bone Resorption in an 8-Year-Old Patient: A Case Report

Acrodermatitis continua of Hallopeau (ACH) is an uncommon inflammatory disease manifesting as sterile pustular eruption of the fingers and toes. The disease is of a chronic relapsing nature and is often refractory to treatment. With longstanding disease, osteitis with consequent bone resorption of the underlying phalanges can occur, leading to disability. While the incidence of ACH is rare in children, complications like osteolysis have not been reported previously in this age group. In this paper, we report the case of an 8-year-old boy with severe ACH complicated by bone resorption

An invasive primary thymoma : a rare cause of intrapulmonary mass

Background: Primary intrapulmonary thymomas are extremely rare tumors and could be mistaken for a variety of benign and malignant epithelial or mesenchymal lesions. Case report: A case of a primary invasive intrapulmonary thymoma manifested with massive hemoptysis is presented. CT demonstrated a mass with specks of calcification, located within the upper lobe of the right lung. The lesion showed heterogeneous enhancement with areas of cystic and necrotic degeneration and hemorrhagic foci. CT differential diagnosis included the possibility of invasive thymoma, which was confirmed by surgery and histopathology. Conclusions: Though a rare entity, intrapulmonary thymoma, because of its potentially invasive and malignant nature, should be included in the radiological differential diagnosis of intrapulmonary masses. This is important, since it can determine further management