Characteristics of chimpanzee population.

<p>Characteristics of the chimpanzee population studied, the HCV-genotype, the time since HCV exposure, HCV-RNA load, serum IP-10levels, and the liver enzymes levels ALT, AST and γGT. The average values and the range are shown.</p

Relation between IP-10 levels and aminotransferases in serum.

<p>Relation between IP-10 and liver enzymes γGT, ALT and AST from HCV-infected individual chimpanzees (A) and HCV-infected patients (B) A significant correlation between the two parameters is defined as r²>0.85 and p<0.05 where “r²” is a measure for correlation and “p” is a measure for the quality if this correlation.</p

γGT, ALT and AST in humans and chimpanzees chronically infected with HCV.

<p>Interquartile range and the median (horizontal line) of γGT, ALT and AST in U/ml in chimpanzees and patients chronically infected with HCV.</p

Characteristics of the patient cohort chronically infected with HCV.

<p>Characteristics of chronic HCV patients studied: HCV genotype, HCV-RNA load, serum IP-10 levels, the levels of liver enzymes ALT, AST and γGT. The average values and the range are presented.</p

Correlation between HCV viremia and IP-10 in serum in chimpanzees.

<p>Box-whisker plots indicate the interquartile range and the median (horizontal line) of IP-10 concentrations in serum from animals of the different groups; “high HCV load” where the virus load of individual animal is higher as compared to median value of 200,000 IU/ml; “low HCV load” where the virus load of individual animal is lower as compared to the median value of 200,000 IU/ml; HCV resolvers and naïve, non-exposed (A). Box-whisker plots indicate the interquartile range and the median (horizontal line) of IP-10 concentrations in serum of humans and chimpanzees with high HCV load (>median virus load) and low HCV load (2>0.85 and p<0.05 where “r²” is a measure for correlation and “p” is a measure for the quality if this correlation.</p