EFFECT OF CERTAIN TETRACYCLINE ANALOGS ON (CARBON-14-LABELED)-PHENYLALANINE INCORPORATION BY ESCHERICHIA COLI B CELL-FREE EXTRACTS

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Design for Meaning of Smart Connected Products

This paper tackles the topic of meaning-driven innovation from a Product Design perspective. It focuses on the design of Smart Connected Products: internet-enabled phygital products that blend hardware and software. This category of products represents a positive field of exploration for meaning-driven innovation. The paper highlights three kinds of meaning that are relevant for Smart Connected Products: the meaningful identity of the object as product category, the meaning of the product in relation to its shape and functionality, and in relation to a phygital ecosystem. The paper reflects on the methods that can support designers in the development of meaningful smart products and presents the “Mapping the IoT” Toolkit, a downloadable tool that guides in specific activities aimed at framing the product’s meaning. Tests with the Toolkit proved the effectiveness of using cards with critical questions as a way to deepen design concepts and reach a common, meaningful vision

Reimagining the Digital Humanities with \u27New Majority\u27 Students for Public Higher Education

When we talk about the digital humanities as scholars and practitioners in higher education, who do we imagine to be the students of this emerging field? How is this connected to efforts to make the digital humanities more inclusive and interdisciplinary

Temperature Controlled High Energy Adjustable Multi-Mode Emission Laser Therapy in the Treatment of the Chronic Low Back Pain

Temperature controlled high energy adjustable multi-mode emission laser therapy (THEAL) is a new physiotherapy method recently introduced in the treatment of musculoskeletal disorders. The first published clinical trials show an excellent clinical response in the treatment oflow back pain (LBP). In view of various protocol modulation modes, we wanted to verify the effect of a protocol that provided contextual administration of different wavelengths. We administered to twenty patients a treatment that consisted of ten sessions of Temperature controlled High Energy Adjustable multi-mode emission Laser therapy (THEAL) (iLux XP/ Ixyon, Mectronic Medicale, Italy), with the simultaneous delivery of 650nm, 810nm and 1064nm wavelengths. The patients have been monitored during different follow-ups(FUs)to check the remission of pain, using Visual Analog Scale (VAS) for pain, Roland Score for functional recovery with and OswestryScore for regression of disability. Already at the end of the treatment after 10 days, and at subsequent FUs time at 1, 2, 4 and 12 months, a significant improvement was noticed for all these scores. These clinical results are consistent with the expected biological effects for each wavelengththat we have administered. The 810nm has a strong affinity for modulating no receptive pain, 650nm wavelengths have a marked anti-inflammatory effect and 1064nm has a decontracting action on muscles. The possibility to use a High Energy Laser with adaptive modulating emission and thermal control of biological tissue (THEAL) allows an optimized energy delivery with good local compliance. The concomitant administration of these wavelengths would therefore enable action on the various pathogenic noxa: radicular pain, local inflammation and reactive muscle response