Chronic Actinic Dermatitis: Two Patients with Successful Management using Narrowband Ultraviolet B Phototherapy with Systemic Steroids

Background. Chronic actinic dermatitis (CAD) is a debilitating photodermatosis with characteristic clinical, histological and photobiological features (reduced minimal erythema dose: MED). Its management involves various therapeutic approaches, among them there is phototherapy. Efficacy of psoralen ultraviolet therapy (PUVA therapy) was previously demonstrated but there are no current data on the use of narrowband ultra violet B (UVB) therapy (NB-UVB) in CAD. NB-UVB has already been proven to be effective and safe in several other photodermatoses. Case reports. We report here two dark-skinned patients (skin type IV and V) with CAD, successfully treated with an incremental regimen of NB-UVB phototherapy coupled to a 3 month-course of systemic steroids (1mg/Kg/day). Conclusion. Our protocol of NB-UVB with steroids seems to be effective for the management of CAD with a good short term safety profile

Adénite granulomateuse révélant un déficit en récepteur de l’IL12

International audienceLettre à la rédactio

Granulome annulaire généralisé, thyroïdite auto-immune et diabète insulinodépendant. A propos d’une observation

Les Auteurs rapportent l’observation d’un granulome annulaire généralisé survenu chez une patiente âgée de 16 ans présentant un diabète de type I. Un bilan immunologique pratiqué dans le cadre de son diabète, découvre des anticorps antimicrosomaux et des anticorps antigliadine de type IgA. La recherche des anticorps antigliadine de type IgG et des anticorps antiendomesium de type IgG était, par ailleurs, négative. Ce bilan traduit l’existence d’une thyroïdite auto-immune associée au diabète et fait suspecter une maladie coeliaque. Cette nouvelle observation de granulome annulaire, survenant sur un terrain dysimmunitaire, vient renforcer l’hypothèse d’une origine auto-immune du granulome annulaire

Tinea capitis favosa due to Trichophyton schoenleinii.

Archives Acta Dermatovenerol Alp Pannonica Adriat (http://www.acta-apa.org/journals/acta-dermatovenerol-apa/papers/10.15570/archive/acta-apa-07-1/7.pdf)International audienceA case of a tinea capitis caused by Trichophyton schoenleinii is presented. It involves a 6-year old Tunisian boy that had presented with diffuse scaling of the scalp misdiagnosed as psoriasis and was treated unsuccessfully with keratolytic shampoos for two years. Tinea favosa due to Trichophyton schoenleinii was confirmed by mycological examination. He was successfully treated with griseofulvin for 6 weeks and topical application of imidazole. Trichophyton schoenleinii is an important anthropophilic dermatophyte that causes tinea favosa. It is transmitted by contagion between humans and is currently endemic in Africa. Ringworm is still frequent in Tunisia, but favus is becoming exceptional due to improvements in living conditions and hygiene