74 research outputs found
Policy impacts on regulating ecosystem services: looking at the implications of 60Â years of landscape change on soil erosion prevention in a Mediterranean silvo-pastoral system
Estruturas secretoras de mucilagem em Hibiscus pernambucensis Arruda (Malvaceae): distribuição, caracterização morfoanatômica e histoquÃmica
Differences in brain activity between fast and slow responses on psychomotor vigilance task:an fNIRS study
Optical monitoring and detection of spinal cord ischemia.
Spinal cord ischemia can lead to paralysis or paraparesis, but if detected early it may be amenable to treatment. Current methods use evoked potentials for detection of spinal cord ischemia, a decades old technology whose warning signs are indirect and significantly delayed from the onset of ischemia. Here we introduce and demonstrate a prototype fiber optic device that directly measures spinal cord blood flow and oxygenation. This technical advance in neurological monitoring promises a new standard of care for detection of spinal cord ischemia and the opportunity for early intervention. We demonstrate the probe in an adult Dorset sheep model. Both open and percutaneous approaches were evaluated during pharmacologic, physiological, and mechanical interventions designed to induce variations in spinal cord blood flow and oxygenation. The induced variations were rapidly and reproducibly detected, demonstrating direct measurement of spinal cord ischemia in real-time. In the future, this form of hemodynamic spinal cord diagnosis could significantly improve monitoring and management in a broad range of patients, including those undergoing thoracic and abdominal aortic revascularization, spine stabilization procedures for scoliosis and trauma, spinal cord tumor resection, and those requiring management of spinal cord injury in intensive care settings
Ultrastructural changes in chloroplasts of Populus tremula L., leaves affected by the fungus Melampsora pinitorqua Braun. Rostr
Fiber-optic monitoring of spinal cord hemodynamics in experimental aortic occlusion
BACKGROUND: Spinal cord ischemia occurs frequently during thoracic aneurysm repair. Current methods to detect ischemia, based upon electrophysiology techniques, are indirect, non-specific, and temporally slow. Here we report the testing of a spinal cord blood flow and oxygenation monitor, based on Diffuse Correlation and Optical Spectroscopies, during aortic occlusion in a sheep model. METHODS: Testing was carried out in sixteen Dorset sheep. Sensitivity in detecting spinal cord blood flow and oxygenation changes during aortic occlusion, pharmacologically induced hypotension and hypertension, and physiologically induced hypoxia/hypercarbia were assessed. Accuracy of the Diffuse Correlation Spectroscopy measurements was determined via comparison to microsphere blood flow measurements. Precision was assessed through repeated measurements in response to pharmacologic interventions. RESULTS: The fiber optic probe can be placed percutaneously, and is capable of continuously measuring spinal cord blood flow and oxygenation preoperatively, intraoperatively, and postoperatively. The device is sensitive to spinal cord blood flow and oxygenation changes associated with aortic occlusion, immediately detecting a fall in blood flow (−65 ± 32%, n=32) and blood oxygenation (−17 ± 13%, n=11) in 100% of trials. Comparison of spinal cord blood flow measurements by the device with microsphere measurements led to a correlation of R(2)=0.49, p<0.01 and the within-sheep coefficient of variation was 9.69%. Finally, Diffuse Correlation Spectroscopy is temporally more sensitive to ischemic interventions than motor evoked potentials. CONCLUSIONS: The first generation spinal fiber optic monitoring device offers a novel and potentially important step forward in the monitoring of spinal cord ischemia
Concise overview of European soil erosion research and evaluation
Soil loss by erosion is a major threat to European soil resources. It is linked to most other threats to soils and is estimated to incur substantial costs to society. To monitor and evaluate soil erosion comprehensively, measurements and modelled estimates of soil loss by erosion need to integrate water, wind and tillage erosion, as these are common throughout Europe. Tolerable rates of soil erosion (thresholds) in Europe can be set equal to estimated soil formation rates, that is, 1 t ha 1 yr 1, but defining this threshold will require further research in the context of soil functions. There is a strong need for improving the knowledge base of current erosion rates, especially to develop and validate reliable erosion prediction models. This should include depositional environments (e.g. flood plains) where greater erosion rates than those on hill slopes may be tolerable, depending on the consequent effects on all relevant ecosystem goods and services provided by soil. Moreover, in considering erosion at catchment (watershed) level, the distance between erosion sites and areas of deposition should be taken into account.publishe
Fiber-optic Monitoring of Spinal Cord Hemodynamics in Experimental Aortic Occlusion
BACKGROUND: Spinal cord ischemia occurs frequently during thoracic aneurysm repair. Current methods to detect ischemia, based upon electrophysiology techniques, are indirect, non-specific, and temporally slow. Here we report the testing of a spinal cord blood flow and oxygenation monitor, based on Diffuse Correlation and Optical Spectroscopies, during aortic occlusion in a sheep model. METHODS: Testing was carried out in sixteen Dorset sheep. Sensitivity in detecting spinal cord blood flow and oxygenation changes during aortic occlusion, pharmacologically induced hypotension and hypertension, and physiologically induced hypoxia/hypercarbia were assessed. Accuracy of the Diffuse Correlation Spectroscopy measurements was determined via comparison to microsphere blood flow measurements. Precision was assessed through repeated measurements in response to pharmacologic interventions. RESULTS: The fiber optic probe can be placed percutaneously, and is capable of continuously measuring spinal cord blood flow and oxygenation preoperatively, intraoperatively, and postoperatively. The device is sensitive to spinal cord blood flow and oxygenation changes associated with aortic occlusion, immediately detecting a fall in blood flow (−65 ± 32%, n=32) and blood oxygenation (−17 ± 13%, n=11) in 100% of trials. Comparison of spinal cord blood flow measurements by the device with microsphere measurements led to a correlation of R(2)=0.49, p<0.01 and the within-sheep coefficient of variation was 9.69%. Finally, Diffuse Correlation Spectroscopy is temporally more sensitive to ischemic interventions than motor evoked potentials. CONCLUSIONS: The first generation spinal fiber optic monitoring device offers a novel and potentially important step forward in the monitoring of spinal cord ischemia
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