34,571 research outputs found
Square lattice hollow core photonic bandgap fibres
We propose a novel photonic bandgap fibre (PBGF) based on a square lattice cladding. The fibre presents a 20% wider bandgap than conventional triangular-lattice-based PBGFs and with a 9-cell core can be effectively single moded
Epidemiology and economic impact of Johne's disease in Irish dairy herds
End of project reportThis project addressed two aspects of an emerging infectious disease of Irish cattle; the epidemiology and the economic impacts of Johne’s disease (paratuberculosis). Though this disease has been present in Irish cattle herds for decades, only since the introduction of the Single European Market in 1992 has it become more widespread. In addition to this change in the epidemiology of the disease in Irish cattle, there is increasing evidence that the causative organism, Mycobacterium avium subsp. paratuberculosis (MAP) may be implicated in a human illness, Crohn’s disease, though proof of a zoonotic link is currently disputed (Tremblay, 2004). Against this background a collaborative research project was set up by Teagasc and funded by Irish dairy farmers
All-optical pulse reshaping and retiming systems incorporating pulse shaping fiber Bragg grating
This paper demonstrates two optical pulse retiming and reshaping systems incorporating superstructured fiber Bragg gratings (SSFBGs) as pulse shaping elements. A rectangular switching window is implemented to avoid conversion of the timing jitter on the original data pulses into pulse amplitude noise at the output of a nonlinear optical switch. In a first configuration, the rectangular pulse generator is used at the (low power) data input to a nonlinear optical loop mirror (NOLM) to perform retiming of an incident noisy data signal using a clean local clock signal to control the switch. In a second configuration, the authors further amplify the data signal and use it to switch a (low power) clean local clock signal. The S-shaped nonlinear characteristic of the NOLM results in this instance in a reduction of both timing and amplitude jitter on the data signal. The underlying technologies required for the implementation of this technique are such that an upgrade of the scheme for the regeneration of ultrahigh bit rate signals at data rates in excess of 320 Gb/s should be achievable
SEM characterization of mm-long nanowires
The fabrication of optical fibre nanowires has recently attracted much attention [1-5]. Nanowires longer than 110mm [2] and with diameters smaller than 20 nm [5] have now been fabricated using a top-down approach. Because of the extraordinarily large ratio between length and diameter (>100000), the characterization of optical fibre nanowires requires instrumentation capable of measuring lengths over a range spanning more than five orders of magnitude. In our experiments dimensional characterization along the nanowire has been performed using an SEM and calibrated references. The samples are first attached to conductive carbon pads to avoid electrostatic build-up. Charging makes accurate metrology difficult because the electron beam can be deflected by the induced electric field on the sample. Fig. 1 illustrates a nanowire with a radius r=30nm wrapped around a microfibre with r=2µm. Variations in radius of another nanowire along its length are shown in fig. 2
Novel Fiber Design for Wideband Conversion and Amplification in Multimode Fibers
We propose an operating principle to achieve broadband and highly tunable
mode conversion and amplification exploiting inter-modal four wave mixing in a
multimode fiber. A bandwidth of 30 nanometers is demonstrated by properly
designing a simple step-index silica fiber.Comment: Ecoc conference 201
Gli2a protein localization reveals a role for Iguana/DZIP1 in primary ciliogenesis and a dependence of Hedgehog signal transduction on primary cilia in the zebrafish
Background: In mammalian cells, the integrity of the primary cilium is critical for proper regulation of the Hedgehog (Hh) signal transduction pathway. Whether or not this dependence on the primary cilium is a universal feature of vertebrate Hedgehog signalling has remained contentious due, in part, to the apparent divergence of the intracellular transduction pathway between mammals and teleost fish.
Results: Here, using a functional Gli2-GFP fusion protein, we show that, as in mammals, the Gli2 transcription factor localizes to the primary cilia of cells in the zebrafish embryo and that this localization is modulated by the activity of the Hh pathway. Moreover, we show that the Igu/DZIP1 protein, previously implicated in the modulation of Gli activity in zebrafish, also localizes to the primary cilium and is required for its proper formation.
Conclusion: Our findings demonstrate a conserved role of the primary cilium in mediating Hedgehog signalling activity across the vertebrate phylum and validate the use of the zebrafish as a representative model for the in vivo analysis of vertebrate Hedgehog signalling
Limited Arbitrage and Short Sales Restrictions: Evidence from the Options Markets
In this paper, we investigate empirically the well-known put-call parity no-arbitrage relation in the presence of short sale restrictions. We use a new and comprehensive sample of options on individual stocks in combination with a measure of the cost and difficulty of short selling, specifically the spread between the rate a short-seller earns on the proceeds from the sale relative to the standard rate (the rebate rate spread). We find that violations of put-call parity are asymmetric in the direction of short sales constraints, their magnitudes are strongly related to the rebate rate spread, and they are maintained even in the presence of transactions costs both in the options and equity lending market. These violations appear to be related to both the maturity of the option and the level of valuations in the stock market, consistent with a behavioral finance theory that relies on over-optimistic investors in the stock market and segmentation between the stock and options markets. Moreover, the extent of violations of put-call parity and the rebate rate spread for individual stocks are significant predictors of future stock returns. For example, cumulative abnormal returns, net of borrowing costs, over a 2«-year sample period can exceed 65%.
Quadrature decomposition of optical fields using two orthogonal phase sensitive amplifiers
We propose a new technique to optically process coherent signals by simultaneously extracting their two (I and Q) quadrature components into two orthogonal polarizations at the same frequency. Two possible implementations are demonstrated
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