Incorporating Seasonality into Agricultural Project Design and Learning

Seasonality can be extremely damaging to the lives and livelihoods of rural people, but this is rarely recognised and factored into the design and implementation of agricultural projects. During the annual hungry season, farmers face empty granaries, high food prices and waterborne diseases, which compel them to adopt ‘coping strategies’ that perpetuate poverty ratchets. Seasonal employment programmes can smooth income and consumption but could overburden women, since seasonal workloads are highly gendered. Incorporating a seasonal perspective into agricultural programming requires building a seasonality assessment into the baseline survey and design phase of agricultural projects, reducing seasonal food insecurity by stabilising rather than maximising crop production, and enhancing seasonality awareness among agricultural advisers and project staff, in each local context. Incorporating seasonality into M&E processes has implications for the timing and frequency of data collection, and requires a deeper understanding of the complexity of livelihood processes between and within rural households

Response to the Consultation on the Tax Deductibility of Corporate Interest Expense

This note is a response to the consultation on the corporate interest expense, published by HM Treasury on October 22, 2015. It reflects the views of the named authors, rather than the Oxford University Centre for Business Taxation, which has no corporate views. Our aim is to address the big picture regarding the nature of relief for the cost of finance. We do not offer answers to most of the questions raised in the consultation document, other than perhaps the first, on whether a general interest restriction should be introduced in the UK

Seagrass Distribution in the Pensacola Bay System, Northwest Florida

Aerial surveys of seagrass coverage in the Pensacola Bay system (PBS) have been conducted during 1960, 1980, 1992 and 2003. This report summarizes the results for the 2003 survey and compares the results to those previously reported for other surveys. The estimated coverage of seagrass for the PBS during 2003 was 1,654 ha. Continuous and patchy coverages ranged from 0 to 684 ha and 11 to 543 ha, respectively, for five PBS subsystems. In 2003, the majority of seagrass coverage occurred in Santa Rosa Sound (76%). Declines in total coverage occurred for East Bay (93%) and Escambia Bay (75%) whereas increases were observed for Pensacola Bay (32%) and Santa Rosa Sound (8%). The approximate 9% decline (about 160 ha or 395 a) in total coverage since 1992 represents an estimated 7 to 8 million dollar loss in ecological services. The changes in coverage are likely due to naturally occurring and anthropogenic factors but it is not possible to differentiate the relative contributions of these factors alone and in combination on seagrass distribution. The ability of seagrasses to exist long-term in Florida’s fourth largest estuarine system is uncertain due to the adverse effects of rapid urbanization in the watershed. Active resource management which includes more frequent in-situ monitoring and aerial assessment and the availability of relevant water and sediment quality criteria protective of submerged aquatic vegetation are needed to prevent future declines

Quality assurance for advocates

This is the final report of a pilot study and evaluation of a mechanism for assessing the quality of criminal defence advocates acting under legal aid

Electrocardiographic detection of left ventricular hypertrophy using echocardiographic determination of left ventricular mass as the reference standard Comparison of standard criteria, computer diagnosis and physician interpretation

Electrocardiographic findings of left ventricular hypertrophy were compared with echocardiographic left ventricular mass in 148 patients to assess performance of standard electrocardiographic criteria, the IBM Bonner program and physician interpretation. On echocardiography, 43% of the patients had left ventricular hypertrophy (left ventricular mass > 215 g). Sokolow-Lyon voltage (S in V1+ R in V5or V6) and Romhilt-Estes point score correlated modestly with left ventricular mass (r = 0.40, p < 0.001 and r = 0.55, p < 0.001, respectively). Sensitivity of Sokolow-Lyon voltage greater than 3.5 mV for left ventricular hypertrophy was only 22%, but specificity was 93%. Point score for probable left ventricular hypertrophy (≥ 4 points) had 48% sensitivity and 85% specificity, whereas definite hypertrophy (≥ 5 points) had 34% sensitivity and 98% specificity. Computer analysis resulted in 45% sensitivity and 83% specificity. Overall diagnostic accuracy of the IBM Bonner program (67%) was better than that of Sokolow-Lyon voltage (62%), but worse than the Romhilt-Estes point score (69% for ≥ 4 points or 70% for ≥ 5 points). Three cardiologists interpreted electrocardiograms independently and in a blinded fashion. Physician sensitivity was 56%, specificity 92% and accuracy 76%. Correlation with left ventricular hypertrophy was good (r = 0.70, p < 0.001).It is concluded that: 1) computer diagnosis of left ventricular hypertrophy by the IBM Bonner program is no more accurate than diagnosis by Sokolow-Lyon or Romhilt-Estes criteria, and 2) physician recognition of left ventricular hypertrophy is more accurate. This suggests that additional information about left ventricular hypertrophy is present in the electrocardiogram that is not detectable by standard criteria or the IBM computer program

Simple and objective prediction of survival in patients with lung cancer: staging the host systemic inflammatory response

Background. Prediction of survival in patients diagnosed with lung cancer remains problematical. The aim of the present study was to examine the clinical utility of an established objective marker of the systemic inflammatory response, the Glasgow Prognostic Score, as the basis of risk stratification in patients with lung cancer. Methods. Between 2005 and 2008 all newly diagnosed lung cancer patients coming through the multidisciplinary meetings (MDTs) of four Scottish centres were included in the study. The details of 882 patients with a confirmed new diagnosis of any subtype or stage of lung cancer were collected prospectively. Results. The median survival was 5.6 months (IQR 4.8–6.5). Survival analysis was undertaken in three separate groups based on mGPS score. In the mGPS 0 group the most highly predictive factors were performance status, weight loss, stage of NSCLC, and palliative treatment offered. In the mGPS 1 group performance status, stage of NSCLC, and radical treatment offered were significant. In the mGPS 2 group only performance status and weight loss were statistically significant. Discussion. This present study confirms previous work supporting the use of mGPS in predicting cancer survival; however, it goes further by showing how it might be used to provide more objective risk stratification in patients diagnosed with lung cancer

942-42 Is Mitral Valve Prolapse with Significant Mitral Regurgitation a Different Condition from Uncomplicated Mitral Prolapse? Results of Family Studies

Mild instances of mitral valve prolapse (MVP) have been suggested to represent variants of normal, whereas individuals with complicated forms of MVP have a distinct medical condition. This hypothesis would predict different phenotypic features and patterns of inheritance in relatives of index cases with complicated or uncomplicated MVP. Accordingly, we performed clinical and echocardiographic assessment of 16 MVP patients with and 76 without moderate to severe mitral regurgitation (MR+and MR– probands) and 60 and 256, respectively, first-degree relatives (MR+ and MR– relatives). MR+ probands were older (p=0.01), more likely to be male (p=0.002), were more overweight (p=0.004) and had higher systolic blood pressures (p=0.05) and larger aortic roots (p=0.034) after the effects of age and body size were taken into account. MR+ and MR– relatives had similar prevalences (27 and 32%) and age distribution of MVP, but affected MR+ relatives were younger (expected because more children and fewer parents of MR+ probands could be evaluated). and more likely to be male. MR+ and MR- relatives were virtually identical in regard to body habitus, blood pressure, the prevalence of auscultatory findings, thoracic bony abnormalities and palpitations and all echo measurements including anterior mitral leaflet thickness. Four instances of significant MR and two MVP-related complications (infective endocarditis and transient ischemic attack) occurred in the 82 relatives of MR– probands as opposed to none among relatives of MR+ probands. In 20 families, one proband or relative with MVP had severe MR and at least one other with MVP (presumably due to the same gene) was free of MR or complications. Thus, MVP with severe MR does not represent a heritable phenotype and commonly coexists with mild forms of MVP in the same family, making their classification as separate conditions illogical and potentially misleading

Comparison of m-mode echocardiographic left ventricular mass measured using digital and strip chart readings: The Atherosclerosis Risk in Communities (ARIC) study

BACKGROUND: Epidemiological and clinical studies frequently use echocardiography to measure LV wall thicknesses and chamber dimension for estimating quantitative measures of LV mass. While echocardiographic M-mode LV images have traditionally been measured using hand-held calipers and strip-chart paper tracings, digitized M-mode LV image measurements made directly on the computer screen using electronic calipers have become standard practice. We sought to determine if systematic differences in LV mass occur between the two methods by comparing LV mass measured from simultaneous M-mode strip chart recordings and digitized recordings. METHODS: The Atherosclerosis Risk in Communities study applied the latter method. To determine if systematic differences in LV mass occur between the two methods, LV mass was measured from simultaneous M-mode strip chart recordings and digitized recordings. RESULTS: We found no difference in LV mass (p > .25) and a strong correlation in LV mass between the two methods (r = 0.97). Neither age, sex, nor hypertension status affected the correlation of LV mass between the two methods. CONCLUSIONS: We conclude that digital estimates of LV mass provide unbiased estimates comparable to the strip-chart method