6 research outputs found
Figure 1
<p><b>A & B</b>: Rare or no (arrows) H/RS cells stained with CD20 in refractory cHL (<b>A</b>) compared to the overexpression of CD20 on H/RS cells in a responder cHL (arrows) (<b>B</b>) (original magnification ×400). <b>C & D</b>: Numerous H/RS cells stained with bcl2 in a refractory cHL (arrows)(<b>C</b>) comparing to rare cells in a responder case (arrow)(<b>D</b>) (original magnification ×400). <b>E & F</b>: TiA1 expressed on numerous small lymphocytes in a refractory cHL (arrows) (<b>E</b>) and less frequent cells stained with this antibody in a responder cHL (arrows) (<b>F</b>) (original magnification ×400). <b>G & H</b>: c-kit stained frequent mast cells in a refractory cHL (arrows) (<b>G</b>) compared to rare mast cells expressing c-kit in a responder cHL (arrows) (<b>H</b>) (original magnification ×400).</p
Characteristics of patients & IHC markers (univariate analysis).
<p><b>Legends</b>: pts = patients sbtype = subtype L = lymphocytes MC = mast cells nber = number IHC:immunohistochemical CV: continuous variable HRS: Hodgkin and Reed Sternberg cells.</p
Primer positions are indicated from the c-Kit sequence published through the NCBI accession number X06182.
<p>Primer positions are indicated from the c-Kit sequence published through the NCBI accession number X06182.</p
Relationship between phenotype and genotype in patients with mastocytosis according to their age of onset.
<p>Data are expressed in number (percentage).</p
Exons 8 through 13 and 17 mutations according to mastocytosis age of onset.
<p>Data are expressed in number (percentage), 816: substitution of valine in 816 codon of <i>c-kit</i>, Other mutations: mutation in exons 8 through 13. WT: absence of mutation in exons 8 through 13 and 17. Complete genotype was not available for 4 816 WT patients; 1 patient in group 1A, 1 in group 1B and 2 in group 2.</p
Description of 5 adult patients with mastocytosis not related to 816 c-kit mutation.
<p>Description of 5 adult patients with mastocytosis not related to 816 c-kit mutation.</p