PTIE Findings: Expanding Promotion and Tenure Guidelines to Inclusively Recognize Innovation and Entrepreneurial Impact

Funded through a grant from the National Science Foundation (Award # CNS-1936073), Oregon State University has led a nationwide effort to identify best practices for the inclusive recognition of innovation† & entrepreneurship (I&E) impact within promotion and tenure (P&T) guidelines. The grant PI for this effort is Rich G. Carter. The Co-PIs are Karl Mundorff, Jana Bouwma-Gearhart, Tuba Özkan-Haller and Irem Tumer. Additional organizing committee members are Julie Risien and Brian Wall. The overarching effort is referred to as Promotion & Tenure Innovation & Entrepreneurship (PTIE)

Pummerer Cyclization Revisited: Unraveling of Acyl Oxonium Ion and Vinyl Sulfide Pathways

Two viable pathways (vinyl sulfide and acyl oxonium ion) for the Pummerer cyclization have been unraveled that expand the reaction scope and capabilities. Use of Bronsted-enhanced Lewis acidity was key to realization of the vinyl sulfide pathway, whereas selective complexation of the sulfur lone pair facilitated the unprecedented acyl oxonium ion pathway. Preliminary mechanistic investigations support these hypotheses. A range of substrates have been explored to understand the reaction parameters

Total Syntheses of Aromatic Abietane Diterpenoids Utilizing Advances in the Pummerer Rearrangement

The first total syntheses of triptobenzene T, vitexifolin C, 4-epi-triptobenzene L, triptobenzene L, and nepetaefolin F have been accomplished through an enantioselective, common intermediate approach and have enabled the confirmation and/or establishment of the absolute stereochemistry of each natural product synthesized. Application of three new and/or underutilized Pummerer reaction pathways proved critical to the synthetic work. A proline sulfonamide-catalyzed Yamada-Otani reaction was used to access the highly functionalized cyclohexane A ring core, including the C-10 all-carbon quaternary stereocenter. Additionally, the importance of the A ring unsaturation for controlling the stereoselectivity during the C-4 alkylation is showcased

Proline sulphonamide-catalysed Yamada–Otani condensation: reaction development, substrate scope and scaffold reactivity

The development of a proline sulphonamide-catalysed method for enantioselective and diastereoselective construction of functionalized cyclohexenones is described. Impact of catalyst structure as well as solvent effects and additives are explored. A significant substrate scope is demonstrated by variation of both the aldehyde and the enone components. Diastereoselective derivatization of the cyclohexenone scaffold illustrates its utility as a building block for chemical synthesis.Keywords: Beta unsaturated ketones, Carbon, Cyclohexenones, Asymmetric synthesis, Addition reactions, Enantioselective construction, Alder reactions, Quaternary stereocenters, Mannich reactions, Alpha, MichaelThis is the publisher’s final pdf. The published article is copyrighted by the Royal Society of Chemistry

Mayall II = G1 in M31: Giant Globular Cluster or Core of a Dwarf Elliptical Galaxy ?

(Abridged version) Mayall II = G1 is one of the brightest globular clusters belonging to M31, the Andromeda galaxy. Our observations with HST/WFPC2 provide data for the (I vs. V-I) and (V vs. V-I) color-magnitude diagrams. From model fitting, we determine a rather high mean metallicity of [Fe/H] = --0.95 +- 0.09, somewhat similar to 47 Tucanae. We find a larger spread in V-I than can be explained by the measurement errors, and we attribute this to an intrinsic metallicity dispersion amongst the stars of G1. So far, only omega Centauri, the giant Galactic globular cluster, has been known to exhibit such an intrinsic metallicity dispersion. Three estimates of the total mass of this globular cluster can be obtained: King mass = 15 x 10^6 with M/Lv ~ 7.5, Virial mass = 7.3 x 10^6 with M/Lv ~ 3.6, and King-Michie mass range from 14 to 17 x 10^6. Although uncertain, all of these mass estimates make G1 more than twice as massive as omega Centauri. Such large masses relate to the metallicity spread whose origin is still unknown (either self-enrichment, an inhomogeneous proto-cluster cloud, or remaining core of a dwarf galaxy). When considering the positions of G1 in the different diagrams defined by Kormendy (1985), G1 always appears on the sequence defined by globular clusters, and definitely away from the other sequences defined by elliptical galaxies, bulges, and dwarf spheroidal galaxies. The same is true for omega Centauri and for the nucleus of the dwarf elliptical NGC 205. This does not prove that all (massive) globular clusters are the remnant cores of nucleated dwarf galaxies.Comment: 24 pages, 5 figures, accepted for publication in AJ (August 2001

Supplementary Material from Nationwide Survey to Gain Understanding of the Current Evaluation of Tenure-line Faculty Members’ I&E in P&T Considerations

This document provides supplementary material from nationwide survey sent to 377 institutions to gain an understanding of the current evaluation of tenure-line faculty members’ innovation and entrepreneurial impact in promotion and tenure considerations. This work was support by the National Science Foundation (Grant # CNS-1936073) and it part of the Promotion & Tenure Innovation & Entrepreneurship (PTIE) effort (PTIE.org)

Highly Regioselective Nitrile Oxide Dipolar Cycloadditions with ortho-Nitrophenyl Alkynes

The dipolar cylcoadditions of ortho-nitrophenyl alkynes with aryl nitrile oxides has been demonstrated. A range of substituents are tolerated on the alkyne. These reactions proceed with excellent levels of regioselectivity. Subsequent functionalization of the isoxazole scaffold has been demonstrated.This is the author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by the Royal Society of Chemistry and can be found at: http://pubs.rsc.org/en/journals/journalissues/ob. Supplementary information is included in the publisher's online version of the article

Highly Enantioselective Construction of Polycyclic Spirooxindoles by Organocatalytic 1,3-Dipolar Cycloaddition of 2-Cyclohexenone Catalyzed by Proline-Sulfonamide

An enantioselective 1,3-dipolar cycloaddition of 2-cyclo-hexene-1-one and azomethine ylide generated in situ from isatin and amino ester was developed by employing proline sulfonamide as the catalyst. Consequently, novel polycyclic spirooxindole scaffolds with three contiguous stereocenters were prepared in high yield (up to 95%) with excellent diastereo- (> 20:1 dr) and enantio-selectivity (up to 99% ee).Keywords: Isatin, Spiro compounds, Organocatalysis, Cycloaddition, Nitrogen heterocycles, Spirooxindole, 2-cyclohexene-1-one, Alkaloids, 1,3-dipolar cycloadditio

'Just open your eyes a bit more': The methodological challenges of researching black and minority ethnic students' experiences of physical education teacher education

In this paper we discuss some of the challenges of centralising 'race' and ethnicity in Physical Education (PE) research, through reflecting on the design and implementation of a study exploring Black and minority ethnic students' experiences of their teacher education. Our aim in the paper is to contribute to ongoing theoretical and methodological debates about intersectionality, and specifically about difference and power in the research process. As McCorkel and Myers notes, the 'researchers' backstage'-the assumptions, motivations, narratives and relations-that underpin any research are not always made visible and yet are highly significant in judging the quality and substance of the resulting project. As feminists, we argue that the invisibility of 'race' and ethnicity within Physical Education Teacher Education (PETE), and PE research more widely, is untenable; however, we also show how centralising 'race' and ethnicity raised significant methodological and epistemological questions, particularly given our position as White researchers and lecturers. In this paper, we reflect on a number of aspects of our research 'journey': the theoretical and methodological challenges of operationalising concepts of 'race' and ethnicity, the practical issues and dilemmas involved in recruiting participants for the study, the difficulties of 'talking race' personally and professionally and challenges of representing the experiences of 'others'. © 2012 Copyright Taylor and Francis Group, LLC

The intrinsic shape of galaxy bulges

The knowledge of the intrinsic three-dimensional (3D) structure of galaxy components provides crucial information about the physical processes driving their formation and evolution. In this paper I discuss the main developments and results in the quest to better understand the 3D shape of galaxy bulges. I start by establishing the basic geometrical description of the problem. Our understanding of the intrinsic shape of elliptical galaxies and galaxy discs is then presented in a historical context, in order to place the role that the 3D structure of bulges play in the broader picture of galaxy evolution. Our current view on the 3D shape of the Milky Way bulge and future prospects in the field are also depicted.Comment: Invited Review to appear in "Galactic Bulges" Editors: Laurikainen E., Peletier R., Gadotti D. Springer Publishing. 24 pages, 7 figure