213 research outputs found

    What are the Alternative to Financing Students in Higher Education during a Period of Retrenchment?

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    Application of an integrated geotechnical and topographic monitoring system in the Lorano marble quarry (Apuan Alps, Italy)

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    PublishedThis is the author accepted manuscript. The final version is available from Elsevier via http://dx.doi.org/10.1016/j.geomorph.2015.04.009Accurate slope stability analysis is essential for human activity in high-risk geological contexts. This may, however, not be enough in the case of quarrying where the dynamic and evolving environment also requires effective monitoring. A well-designed monitoring system requires the acquisition of a huge dataset over time, improving knowledge of the study area and helping to refine prediction from stability analysis.This paper reports the implementation of an integrated monitoring system in a marble quarry in the Apuan Alps (Italy) and some of the results obtained. The equipment consists of a traditional geotechnical monitoring system (extensometers, crackmeters and clinometers) and two modern topographic monitoring systems (a terrestrial interferometer and a robotic total station). This work aims to provide in-depth knowledge of the large scale rock mass behaviour as a result of marble exploitation, thereby allowing continuous excavation. The results highlight the importance of integrating different monitoring systems.The present study was undertaken within the framework of the Italian National Research Project PRIN2009, funded by the Ministry of Education, Universities and Research, which involves the collaboration between the University of Siena, “La Sapienza” University of Rome, and USL1 of Massa and Carrara (Mining Engineering Operative Unit - Department of Prevention)

    Geological 3D modeling for excavation activity in an underground marble quarry in the Apuan Alps (Italy)

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    The three-dimensional laser scanning technique has recently become common in diverse working environments. Even in geology, where further development is needed, this technique is increasingly useful in tackling various problems such as stability investigations or geological and geotechnical monitoring. Three-dimensional laser scanning supplies detailed and complete geometrical information in short working times, as a result of the acquisition of a large number of data-points that accurately model the detected surfaces. Moreover, it is possible to combine these data with high quality photographic images so as to provide important information for geological applications, as follows. A working approach, that combines terrestrial laser scanning and traditional geological surveys, is presented. A three-dimensional model, that includes information about the geological structure in an underground quarry in the Apuan Alps, is realized. This procedure is adaptable to other geological contexts, and because of its operating speed and accuracy it is invaluable for optimal excavation, in which a proper planning of quarrying activity is vital for safety and commercial reasons. © 2014 Elsevier Ltd.The authors gratefully acknowledge the assistance of the personnel of the Romana Quarry and particularly Geol. Massimo Corniani. This paper was possible because of support from the Tuscany Region Research Project known as “Health and safety in the quarries of ornamental stones – SECURCAVE”

    Magnetic-Oriented Nickel Particles and Nickel-Coated Carbon Nanotubes: An Efficient Tool for Enhancing Thermal Conductivity of PDMS Composites

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    In this study, PDMS composites are thermally cured with nickel particles and nickel-coated carbon nanotubes as fillers. Both fillers are oriented with the aim to increase the thermal conductivity of the silicone polymer network, due to the formation of a continuous thermal path. Scanning electron microscopy (SEM) gives a picture of the polymer network's morphology, proving the effective alignment of the nickel particles. Rheology and attenuated total reflectance Fourier transform infrared spectroscopy (ATR-FTIR) studies confirm the full curing of the silicon network and no influence in the curing kinetics of the type and content of fillers and their orientation. Dynamic mechanical thermal analysis (DMTA) and tensile analysis show instead different thermo-mechanical behavior of the polymer network due to the presence of different fillers, different fillers percentage, and orientation. Finally, the thermal transmittance coefficient (k) is studied by means of hot disk analysis, revealing the increment of almost 200% due to magnetic filler orientation

    An integrated remote sensing-GIS approach for the analysis of an open pit in the Carrara marble district, Italy: slope stability assessment through kinematic and numerical methods

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    PublishedJournal Article© 2015 Elsevier Ltd. Over the last decade, terrestrial laser scanning and digital terrestrial photogrammetry techniques have been increasingly used in the geometrical characterization of rock slopes. These techniques provide innovative remote sensing tools which overcome the frequent problem of rock slope inaccessibility. Comprehensive datasets characterizing the structural geological setting and geometry of the slopes can be obtained. The derived information is very useful in rock slope investigations and finds application in a wide variety of geotechnical and mine operations. In this research an integrated remote sensing - GIS approach is proposed for the deterministic kinematic characterization of the Lorano open pit in the Apuan Alps of Italy. Based on the results of geomatic and engineering geological surveys, additional geomechanical analysis using a 3D finite difference method will be presented in order to provide a better understanding of the role of stress-induced damage on slope performance

    One year in review 2020:comorbidities, diagnosis and treatment of primary Sjogren's syndrome

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    Primary Sjogren's syndrome (pSS) is a complex and heterogeneous disorder characterised by a wide spectrum of glandular and extra-glandular features. The discovery of novel biomarkers allowed to characterise the disease not only phenotypically on the basis of clinical presentation, but also on the basis of the endotype. Moreover, a better stratification of patients has important value in the evaluation of mechanisms underlying the risk of lymphoproliferative disorders in these patients. Finally, novel targeted therapies may open new possibilities for the application of personalised medicine in pSS

    One year in review 2020:comorbidities, diagnosis and treatment of primary Sjogren's syndrome

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    Primary Sjogren's syndrome (pSS) is a complex and heterogeneous disorder characterised by a wide spectrum of glandular and extra-glandular features. The discovery of novel biomarkers allowed to characterise the disease not only phenotypically on the basis of clinical presentation, but also on the basis of the endotype. Moreover, a better stratification of patients has important value in the evaluation of mechanisms underlying the risk of lymphoproliferative disorders in these patients. Finally, novel targeted therapies may open new possibilities for the application of personalised medicine in pSS

    Coating of bioactive glasses with chitosan: The effects of the glass composition and coating method on the surface properties, including preliminary in vitro results

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    Two bioactive glasses were coated with chitosan: SCNB belongs to the SiO2-CaO-Na2O system, and SCNA has the addition of Al2O3 to enhance chemical stability. Different coating methods were compared: direct physical attachment, surface activation through tresyl chloride, and polydopamine as a linker. The samples were char-acterized through SEM-EDS, contact angle measurements, FTIR, zeta potential titrations, tape tests, in vitro precipitation of hydroxylapatite (bioactivity), and cell cultures (RAW 264.7 and UMR-106) on some selected samples. Direct physical attachment (in acetic acid) or use of polydopamine allowed complete surface coverage, while it dropped to one-quarter on both glasses by using tresyl chloride. The coating had a contact angle of about 80 degrees and it well showed typical functional groups (FTIR). The coatings on SCNA were chemically and mechan-ically stable (classified as 4-5B by the tape tests, partially maintained after soaking for 14 days), and showed an isoelectric point around 8. On SCNB, the coatings were unstable (classified as 0-3B, dissolved during soaking) but bioactivity was preserved. The coating affected the biological outcome of SCNA with M0/M1 polarization (1 day) and reduced viability of macrophages (3 days), while osteoblastic cells showed poor adhesion but maintained cell viability and osteogenic potential (3-7 days)
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