5,866 research outputs found
Illegal Immigration and Media Exposure: Evidence on Individual Attitudes
Illegal immigration has been the focus of much debate in receiving countries, but little is known about what drives individual attitudes towards illegal immigrants. To study this question, we use the CCES survey, which was carried out in 2006 in the United States. We find evidence that - in addition to standard labor market and welfare state considerations - media exposure is significantly correlated with public opinion on illegal immigration. Controlling for education, income and ideology, individuals watching Fox News are 9 percentage points more likely than CBS viewers to oppose the legalization of undocumented immigrants. We find an effect of the same size and direction for CNN viewers, whereas individuals watching PBS are instead more likely to support legalization. Ideological self-selection into different news programs plays an important role, but cannot entirely explain the correlation between media exposure and attitudes about illegal immigration.Immigration, Illegal Immigration, Attitudes, Preferences, Media
Impact of monotherapy on HIV-1 reservoir, immune activation, and co-infection with Epstein-Barr virus
Abstract
Objectives
Although monotherapy (mART) effectiveness in maintaining viral suppression and CD4 cell count has been extensively examined in HIV-1-infected patients, its impact on HIV-1 reservoir, immune activation, microbial translocation and co-infection with Epstein-Barr Virus (EBV) is unclear.
Methods
This retrospective study involved 32 patients who switched to mART; patients were studied at baseline, 48 and 96 weeks after mART initiation. Thirty-two patients who continued combined antiretroviral therapy (cART) over the same period of time were included in the study. Markers of HIV-1 reservoir (HIV-1 DNA and intracellular HIV-1 RNA) were quantified by real-time PCR. Markers of T-(CD3(+)CD8(+)CD38(+)) and B-(CD19(+)CD80/86(+) and CD19(+)CD10-CD21(low)CD27(+)) cell activation were evaluated by flow cytometry. Plasma levels of microbial translocation markers were quantified by real-time PCR (16S ribosomal DNA and mitochondrial [mt] DNA) or by ELISA (LPS and sCD14). EBV was typed and quantified by multiplex real-time PCR.
Results
At baseline, no differences were found between mART and cART groups. Three (10%) mART-treated patients had a virological failure vs none in the cART group. Levels of HIV-1 DNA, intracellular HIV-1 RNA and EBV-DNA remained stable in the mART group, while decreased significantly in the cART group. Percentages of T-and B-activated cells significantly increased in the mART-treated patients, while remained at low levels in the cART-treated ones (p = 0.014 and p<0.001, respectively). Notably, levels of mtDNA remained stable in the cART group, but significantly rose in the mART one (p<0.001).
Conclusions
Long-term mART is associated with higher levels of T-and B-cell activation and, conversely to cART, does not reduce the size of HIV-1 reservoir and EBV co-infection
Validation of an adapted Italian-language version of the Sociocultural Attitudes Toward Appearance Questionnaire-3 (SATAQ-3), within a female population: the Sociocultural Attitudes Toward Appearance Questionnaire - Social Media (SATAQ-SM)
Sociocultural Attitudes Towards Appearance Questionnaire-Social Media (SATAQ-SM) is a self-administered questionnaire for the evaluation of social media pressure and internalization of beauty standards. This study aims to validate the SATAQ-SM an adapted Italian version of the Sociocultural Attitudes Towards Appearance Questionnaire third version (SATAQ-3). Confirmatory factor analysis was used to investigate whether the empirical data fitted the four-factor structure of SATAQ-3. Assessment of goodness-of-fit was based on standard model fit criteria: relative chi(2) value (chi(2)/df), Root Mean-Squared Error of Approximation (RMSEA), Comparative Fit Index (CFI) and Tucker-Lewis Index (TLI). Internal consistency was assessed using McDonald's omega. Criterion validity was calculated by correlating the SATAQ-SM factors scores with the total score of the Rosenberg self-esteem scale (RSES) and Eating Attitudes Test (EAT-26). Four-hundred and eighty-five females agreed to participate in the study. The four-factor model appears to be confirmed by the fit indices: chi(2)/df = 3.73, RMSEA = 0.07, CFI = 0.99 and TLI = 0.99. All the items defining the four factors had a factor loading of >= 0.40. McDonald's omega of the entire questionnaire was equal to 0.95 and for the four subscales it did not assume values lower than 0.81. The correlations between the factor score of SATAQ-SM and the RSES were all negative and statistically relevant (p < 0.001); the correlations between the scores of the SATAQ-SM subscales and the total score of the EAT-26 are all positive and statistically significant. SATAQ-SM demonstrated good psychometric properties to assess the influence of social media on body image perception related to social media
A rapid magnetic solid phase extraction method followed by liquid chromatography-tandem mass spectrometry analysis for the determination of mycotoxins in cereals
Mycotoxins can contaminate various food commodities, including cereals. Moreover, mycotoxins of different classes can co-contaminate food, increasing human health risk. Several analytical methods have been published in the literature dealing with mycotoxins determination in cereals. Nevertheless, in the present work, the aim was to propose an easy and effective system for the extraction of six of the main mycotoxins from corn meal and durum wheat flour, i.e., the main four aflatoxins, ochratoxin A, and the mycoestrogen zearalenone. The developed method exploited magnetic solid phase extraction (SPE), a technique that is attracting an increasing interest as an alternative to classical SPE. Therefore, the use of magnetic graphitized carbon black as a suitable extracting material was tested. The same magnetic material proved to be effective in the extraction of mycoestrogens from milk, but has never been applied to complex matrices as cereals. Ultra high-performance liquid chromatography tandem mass spectrometry was used for detection. Recoveries were > 60% in both cereals, even if the matrix effects were not negligible. The limits of quantification of the method results were comparable to those obtained by other two magnetic SPE-based methods applied to cereals, which were limited to one or two mycotoxins, whereas in this work the investigated mycotoxins belonged to three different chemical classes
Genetic diversity in Sicilian populations of Quercus ilex (Fagaceae)
Recent studies on the genetic structure of the Italian populations of Quercus ilex demonstrated their high diversity, particularly in the Sicilian metapopulation. In order to check if the holm oak stands in the mountains of NW Sicily could have some relationship with Q. ilex subsp. bal- lota (distributed in Spain and NW Africa), 26 specimens from the Sicilian most distinctive Q. ilex populations have been compared with some representative populations of the Italian Peninsula, North Africa and Spain, by means of the ISSR technique. Even if the results are too preliminary to confirm or reject the initial hypothesis, they confirmed an high level of genetic variability, well distributed among the analyzed specimens. In particular, the metapopulations from the Sicilian mountains (Quacella, Vallone Canna) revealed some genetic affinity with those of the Moroccan mountains (Marrakech/Oukaimeden and Ifrane). These populations, on their turn, resulted to be quite distant from the sample from SE-Spain (Sierra de Javalambre). Moreover, a certain genetic distance has been detected from the comparison of the mountain populations of Sicily with those of coastal sites of this Island (Scopello, Castellammare) and Capri (Villa Jovis)
What makes a patient engaged: a multilevel integrative review of factors contributing to patient engagement.
Background: Scholars and practitioners from diverse disciplines are increasingly exploring Patient Engagement (PE), defined as individual consensus and participation in health treatment. However, this heightened attention has generated contention over PE's definition and promotion. This study addresses the challenge through a multilevel integrative review to deepen PE understanding.
Methods: Using the umbrella review approach, we synthesized literature from different disciplines (e.g., psychology, healthcare studies, medicine) by classifying antecedents of PE at different levels, namely from the individual level to the societal level.
Findings: Our multilevel review provides an integrated understanding of PE as a multidimensional concept with antecedents and implications across various levels. At the individual level, we identified intra- and inter-individual factors with elements (e.g., trust, expectations, autonomy, motivation) shaping the PE experience. The task level included factors related to treatment, illness type, and technological devices, with specific elements (e.g., demands, usability, duration). The relational level encompassed healthcare providers and patients' perspectives (e.g., interprofessional communication, collaboration, and goal setting). The organizational level included factors like work environment planning, organizational resources, and policies, with specific elements (e.g., care planning and accessibility). The societal level considered factors like access to health programs and societal/cultural accounts (e.g., public/private distinctions and patient-centered care/approach).
Discussion: This contribution introduces an integrated model, expanding perspectives beyond the traditional individual PE model to encompass multiple factors, including organizational and social spheres. The proposed multilevel perspective is applied for theoretical considerations (e.g., identifying antecedents and facilitating factors) and practical applications (e.g., enhancing healthcare service quality)
On-line separation and determination of trivalent and hexavalent chromium with a new liquid membrane annular contactor coupled to inductively coupled plasma optical emission spectrometry
We describe a new on-line sensitive and selective procedure for the determination of trivalent and hexavalent chromium in liquid samples by a tailor-made contactor (TMC), specifically a liquid membrane annular TMC, coupled with inductively coupled plasma with optical detection. The TMC was designed and developed to integrate the extraction and stripping phases of the analyte in one module to minimize the membrane solvent’s consumption and maximize the speed of transport through the liquid membrane. Moreover, the particular geometry studied, which consists of two coaxial hollow fibers, allows the TMC to be used for both separating and preconcentrating purposes. Both (−)-N-dodecyl-N-methylephedrinium bromide (30 mM) in dichloroethane and HNO3 (0.75 M) were used as the liquid membrane and receiving solution, re-spectively. The proposed method’s performance was evaluated in terms of the hexavalent chro-mium extraction efficiency and the coefficient of variation percentages; these were higher than 85% and less than 5%, respectively. In addition, the proposed procedure was applied to two real sam-ples: a tap water sample and an eluate from solid urban waste. In both cases, the analytical per-formances were good and comparable to those obtained using synthetic standard solutions
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