692 research outputs found
Hemoglobin life-threatening value (1.9 g/dl) in good general condition: a pediatric case-report
Abstract Background We report a pediatric patient presenting in good general condition despite a hemoglobin value of 1,9 g/dL, which is normally regarded as life-threatening. Case presentation An African 5 years-old girl presented to our Emergency Department (ED) for worsening asthenia, within a clinical picture of good general condition. The hemoglobin value at admission was 1,9 g/dL. The subsequent diagnostic-therapeutic pathway highlighted the presence of two different causes, both well known to be responsible for chronic anemia (with slow reduction of hemoglobin values): iron deficiency anemia (IDA) due to a very low dietary intake of iron-rich foods, and homozygous sickle cell disease (HbSS). She received transfusions of packed red blood cells (overall 15 ml/kg) and subsequently intravenous iron preparations (total amount 200 mg) followed by oral iron supplements. The Hb value at discharge, 10 days after the admission, was 9.8 g/dL. Conclusions When approaching a picture of severe anemia, we suggest pediatricians take into consideration clinical conditions rather than laboratory values and to take advantage of detailed anamnestic data in order to make the diagnosis
Dynamic of Native Pasture Influenced by Deferment of Grazing and Fertilization
Native pastures of southern Brazil cover 12 million ha and are the main forage feed resource for most domestic livestock. However, their heavy and continuous use has reduced standing biomass and the presence of good forage species, reducing animal performance and jeopardizing the ecosystem sustainability. An alternative for better use of these pastures and their preservation is grazing deferment that allow natural reseeding. The objective of this research was evaluate native pasture dynamic after six years of grazing deferments (GD) periods and soil fertilization effects by point-quadrat method every season. All pasture components were affected by GD, with prostrate grasses increasing their frequency (P \u3c 0.05) under continuous grazing while periods of rest encouraged erect plants. Fertilization improved pasture condition by reducing frequencies of no forage species, litter and bare soil, and increasing frequencies and dry matter contribution of good ones like native legumes, especially Desmodium incanum
Investigation on virucidal activity of chlorine dioxide. Experimental data on Feline calicivirus, HAV and Coxsackie B5
Introduction. The aim of this study was to evaluate the efficacy
of ClO2 with regard to viruses which show a particular resistance
to oxidizing agent such as HAV and Norwalk and Norwalk-like
viruses, and which play an important role in the epidemiology of
viral foodborne diseases.
In the food industry, disinfection of processing systems and equipment
is a very important instrument to prevent secondary contamination
and to guarantee food safety. Among disinfectants,
chlorine dioxide (ClO2) presents a good efficacy at wide range
of pH values, its action is rapid and generates few reaction byproducts
if compared to hypoclorite. Experimental studies have
highlighted that ClO2 shows a good bactericidal activity and it is
also active towards viruses. Furthermore, the low concentrations
and low contact times required to obtain microbial load reduction
are favourable elements for the application of this compound in
the industrial sanitizing practices.
Methods. As it is impossible to cultivate the Norwalk virus in vitro,
we tested the resistance of Feline calicivirus (F9 strain) vs. ClO2, in
comparison with HAV (strain HM-175) and CoxsackieB5. Chlorine
dioxide was used at concentrations ranging from 0.2 to 0.8 mg/l in
water solution, at pH 7 and at +20 °C. Viral suspensions were added
to disinfecting solution and, at pre-set times, were sampled to undergo
to titration after blocking the disinfectant action with thiosulphate 0.05
M. On the basis of the data obtained, for each virus and in relation
to different concentrations, mean reduction times were calculated for
99%, 99.9% and 99.99% using the regression analysis model.
Results. As regards Feline calicivirus, at a concentration of 0.8
mg/l of ClO2, we obtained the complete elimination of the viral
titre in 2 min while 30 min were required at concentrations of 0.2
mg/l. Coxackie B5 showed a similar behaviour, being completely
inactivated in 4 min with 0.4 mg/l of ClO2 and after 30 min at a
concentration of 0.2 mg/l. Inactivation was quicker for HAV, which
was eliminated after only 30 sec at a concentration of 0.8 mg/l and
after 5 min at 0.4 mg/l.
Conclusion. Our data show that for complete inactivation of HAV
and Feline calicivirus, concentrations ? 0.6 mg/l are required.
This observation is true for Coxsackie B5 too, but this virus has
shown a good sensitivity at all concentration tested according to
regression analysis results. For Feline calicivirus and HAV, at
low concentrations of disinfectant, prolonged contact times were
needed to obtain a 99.99% reduction of viral titres (about 16 and
20 minutes respectively)
An observation methodology for non-measurable rotorcraft states
In an attempt to reduce acoustic pollution due to terminal flight phases (lift-offs and landings) in the surroundings of heliport, project MANOEUVRES developed a device capable of estimating the acoustic footprint of helicopters on the ground. This device requires knowledge of certain quantities that cannot be directly measured through physical sensors: the tip-path plane angle of attack and the main rotor thrust coefficient. Previous research has demonstrated that these quantities can be accurately estimated using observers that are properly fed with directly measurable flight mechanics and rotor state variables. However, these observers, which are based on linear mathematical models identified offline and employed through interpolation with respect to nominal airspeed, have shown poor robustness when the number of identification input cases is reduced, as required for a realistic design of observers in the field. This issue has particularly emerged when non-trimmed manoeuvres were considered during observation testing. To address this issue, this paper introduces a new baseline for the observation model, which includes dynamic pressure as an additional input. Moreover, a different model structure is considered depending on the observed variable. Specifically, for the tip-path plane angle of attack, a single model covers the entire airspeed range, while observation models for the rotor thrust coefficient are interpolated based on flight altitude. This new approach demonstrates results of comparable or superior quality to previous observation models. Furthermore, it exhibits increased robustness when the pool of identification cases used for observer synthesis is significantly reduced. Such improved performance and ease of synthesis pave the way for the setup and adoption of the proposed observers in the field
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