ETUDE D’UNE STRUCTURE DE LIAISON PAR FIBRE OPTIQUE : CARACTERISATION DE LA PROPAGATION ET BILAN ENERGETIQUE

Les communications par fibres optiques sont caractérisées par une demande croissante en termes de capacité de transmission. L'objectif est de transmettre de plus en plus de données sans atténuation en minimisant les pertes. Ce mémoire a pour objectif d'étudier de plus près les limitations qui affectent le signal lors de sa propagation on donnant une attention particulière au bilan énergétique d’une liaison par fibre optique. Tous les effets de dispersion et les effets non linéaires ont été discutés

Validity of Prostate Health Index and Percentage of [-2] Pro-Prostate-Specific Antigen as Novel Biomarkers in the Diagnosis of Prostate Cancer: Omani Tertiary Hospitals Experience

Objectives: Prostate cancer is the leading cancer in older men. The Ministry of Health Oman Cancer Incidence Registry 2013 lists cancer of the prostate as the first most common cancer in males. Therefore, early detection is important and prostate-specific antigen (PSA) is widely used as an established laboratory test. However, despite its wide use, its value in screening, particularly in asymptomatic males, is controversial when considering the risks and benefits of early detection. Methods: This prospective, observational study included 136 males (67.0±8.9 years; range 45–90) who were scheduled for a prostate biopsy in two different tertiary care teaching hospitals in Oman: the Royal Hospital and Sultan Qaboos University Hospital. Blood specimens from these patients were collected at the same setting before obtaining a prostatic biopsy. Three PSA markers (total PSA (tPSA), free PSA (fPSA), and [-2]proPSA (p2PSA)) were measured and the Prostate Health Index (phi) calculated. The histopathological report of the prostatic biopsy for each patient was obtained from the histopathology laboratory of the concerned hospital along with clinical and laboratory data through the hospital information system. Results: Phi has the highest validity markers compared with other prostate markers, with a sensitivity of 82.1%, specificity of 80.6%, and area under the curve (AUC) value of 0.81 at a cutoff of 41.9. The other prostatic markers showed sensitivities and specificities of 78.6% and 25.9% for tPSA; 35.7% and 92.6% for %fPSA; and 64.3% and 82.4% for %p2PSA, respectively. The AUCs at the best cutoff values were 0.67 at 10.1 µg/L for tPSA; 0.70 at 11.6% for %fPSA; and 0.55 at 1.4% for %p2PSA. An association between phi values and aggressiveness of prostate malignancy was noted. Of the 28 patients with prostate cancer, 22 patients had tPSA > 4 µg/L. However, no patient had phi in the low-risk category, and five, six, and 17 patients had phi in the moderate-, high-, and very high-risk categories, respectively. Conclusions: Phi outperforms tPSA and fPSA when used alone or in combination, and appears to be more accurate than both markers in excluding prostate cancer before biopsy. Use of this biomarker helps clinicians to avoid unnecessary biopsies, particularly in patients with gray-zone tPSA level. Phi is the strongest marker that correlates proportionally with Gleason Score; therefore, it is also useful in predicting the aggressiveness of the disease. This is the first reported experience for the use of p2PSA and phi in Oman, the Middle East, and North Africa

Abstracts of the First International Conference on Advances in Electrical and Computer Engineering 2023

This book presents extended abstracts of the selected contributions to the First International Conference on Advances in Electrical and Computer Engineering (ICAECE'2023), held on 15-16 May 2023 by the Faculty of Science and Technology, Department of Electrical Engineering, University of Echahid Cheikh Larbi Tebessi, Tebessa-Algeria. ICAECE'2023 was delivered in-person and virtually and was open for researchers, engineers, academics, and industrial professionals from around the world interested in new trends and advances in current topics of Electrical and Computer Engineering. Conference Title: First International Conference on Advances in Electrical and Computer Engineering 2023Conference Acronym: ICAECE'2023Conference Date: 15-16 May 2023Conference Venue: University of Echahid Cheikh Larbi Tebessi, Tebessa-AlgeriaConference Organizer: Faculty of Science and Technology, Department of Electrical Engineering, University of Echahid Cheikh Larbi Tebessi, Tebessa-Algeri