The Antioxidant Activity of Datura innoxia: New Antioxidant of Natural Origin in Food Industry

Introduction: The significance of medicinal plants as a source of active drugs emerged from the compounds that produces an obvious physiological action on the biological system. Phenolic compounds, alkaloids, tannins and flavonoids have been recognized as the most important bioactive compounds of plants. The present study is designed to evaluate the antioxidant ability of Datura innoxia petals in comparison with ascorbic acid. Materials and Methods: In this research, Datura innoxia petals were collected from Sabzevar city. Methanol extract was prepared by maceration method. Phytochemical screening and antioxidant activity of methanol extract was assessed by 1,1-diphenyl-2picrylhydrazyl (DPPH) assay. Results: Phytochemical screening revealed the presence of alkaloids, saponins, reluctant carbohydrates, cardiac glycosides, flavonoids, terpenoids, coumarins and free anthraquinones. The results indicated that the leaflets contained alkaloids, saponins, flavonoids, coumarins and tannin without cardiac glycosides, terpenoids, free and combined anthraquinone and steroids. The results also showed that the methanolic extract of Petal parts of the Datura innoxia has antioxidant activity with half percent inhibition of free radicals (SC50) that is equal to 31.183 ± 0.302 µg/ml and 28.195 ± 0.259 µg/ml for 60 and 90 minutes. Conclusion: The results indicated that the methanolic extract of Datura innoxia has antioxidant activity that is due to the presence of flavonoids and polyphenols

Clinique de la sexualité : diagnostiquer la différence ou le lieu de l’hétéronormativité

The therapeutic consultations are based on a theoretical discourse in which heteronormativity and androcentrism were denounced long ago by feminists (Irigaray 1974; Wittig, 2007; Horney, 2009). But, despite these critical works, the social progress in the areas of sexual health, and the recognition of the rights of sexual minorities, a moralistic vision, negative or conservative, remains strongly rooted in the disciplines and practice of psychotherapy. Based on interviews conducted among users of French psychotherapies, this article questions the place of norms in training and psychological discourse

Green synthesis of NiO nanoparticles using Calendula officinalis extract: Chemical charactrization, antioxidant, cytotoxicity, and anti-esophageal carcinoma properties

In this study, nickel nanoparticles (NiONPs) have been successfully synthesized in an aqueous medium using the aqueous extract from the leaves of Calendula officinalis. The synthesized NiONPs were characterized using different techniques. According to the XRD analysis, the mean crystal size for NiONPs was found to be 33.17 nm. In addition, SEM images exhibited a uniform spherical morphology with a size of 60.39 nm for the NiONPs. The anti-esophageal carcinoma potentials of C. officinalis leaf aqueous extract, and NiONPs were assessed by the MTT assay against distal esophageal adenocarcinoma (FLO-1), gastroesophageal junction adenocarcinoma (ESO26), human caucasian esophageal carcinoma (OE33), and human esophageal squamous cell carcinoma (KYSE-270) cell lines. This study showed that NiONPs had excellent cell death and anti-cancer effects against esophageal carcinoma cell lines. The IC50 of NiONPs were 380, 263, 229, and 251 µg/mL against FLO-1, ESO26, OE33, and KYSE-270 cell lines, respectively. Among the studied cell lines, the best anti-esophageal cancer activities of NiONPs were gained in the cell line of OE33. The antioxidant activity of NiONPs was investigated using the DPPH test. In the antioxidant test, NiONPs prevented the oxidation of 50 of the DPPH molecules at a concentration of 204 µg/mL. Considering the obtained results, it can be suggested that NiONPs may be administrated as a chemotherapeutic supplement/drug to treat esophageal carcinoma. © 2021 The Author(s