Graphite carbon nitride-modified screen-printed electrode as a highly sensitive and selective sensor for detection of amaranth

This work presented a particular electrochemical sensor for analysis of amaranth, an azo toxic dye. A graphite nitride carbon (g-C3N4) was used to modify an electro-treated screen-printed electrode (g-C3N4/SPE) for electroanalysis of amaranth. Physicochemical characteristics and analytical performance of g-C3N4/SPE were investigated by relevant equipment. The g-C3N4/SPE when comparing with bare SPE, possessed an impressive electrocatalytic performance towards the amaranth oxidation. As-developed sensor under the optimal circumstances exhibited an extended linear response range for different amaranth concentrations of 0.08 μM–340.0 μM, with a narrow practical limit of detection (LOD) of 0.02 μM, a limit of quantification (LOQ) of 0.08 μM, and an unparalleled sensitivity of 0.0702 μA/μM using differential pulse voltammetry (DPV). The applicability of as fabricated sensor was verified by determining the amaranth in real samples, with acceptable recoveries

Short Communication Effect of trifluoperazine on carrageenan-induced acute inflammation in intact and adrenalectomized rats

Abstract: The aim of present study was to investigate the effect of trifluoperazine (TFP) on carrageenaninduced rat's paw edema in intact and adrenalectomized (ADX). TFP (0.2 and 8 mg/kg) were given intraperitoneally just before the intraplantar injection of 0.1 ml of 0.5% carrageenan solution. After four hours, paw edema was assessed by calculating the paw volume changes and extravasations of Evans blue dye as inflammatory indicators. In both ADX and control groups, administration of TFP reduced inflammatory parameters (paw volume and tissue content of Evans blue dye) in inflamed paw. Our findings suggest that TFP can effectively reduce carrageenan-induced paw edema in both ADX and control rats. Therefore, antiinflammatory effect of these drugs does not need the adrenal gland activity