Teaching Power as an Inconvenient but Imperative Dimension of Critical Leadership Development

A central focus of critical leadership development involves identifying and understanding how power flows through society. This requires a complex understanding of social systems. This chapter explores how leadership educators can more explicitly integrate learning related to power dynamics into leadership development initiatives.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/144248/1/yd20299_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/144248/2/yd20299.pd

Sex and Sleep: Perceptions of Sex as a Sleep Promoting Behavior in the General Adult Population

Objective: The main aim of this study was to explore the perceived relationship between sexual activities, sleep quality, and sleep latency in the general adult population and identify whether any gender differences exist.Participants/methods: We used a cross-sectional survey to examine the perceived relationship between sexual activity and subsequent sleep in the general adult population. Seven-hundred and seventy-eight participants (442 females, 336 males; mean age 34.5 ± 11.4 years) volunteered to complete an online anonymous survey at their convenience.Statistical Analyses: Chi square analyses were conducted to examine if there were any gender differences between sexual activities [i.e., masturbation (self-stimulation), sex with a partner without orgasm, and sex with a partner with orgasm] and self-reported sleep.Results: There were no gender differences in sleep (quality and onset) between males and females when reporting sex with a partner [χ(2)2 = 2.20, p = 0.332; χ(2)2=5.73, p = 0.057] or masturbation (self-stimulation) [χ(2)2 = 1.34, p = 0.513; χ(2)2 = 0.89, p = 0.640] involved an orgasm.Conclusions: Orgasms with a partner were associated with the perception of favorable sleep outcomes, however, orgasms achieved through masturbation (self-stimulation) were associated with the perception of better sleep quality and latency. These findings indicate that the public perceive sexual activity with orgasm precedes improved sleep outcomes. Promoting safe sexual activity before bed may offer a novel behavioral strategy for promoting sleep

Exercising Caution Upon Waking–Can Exercise Reduce Sleep Inertia?

Sleep inertia, the transitional state of reduced alertness and impaired cognitive performance upon waking, is a safety risk for on-call personnel who can be required to perform critical tasks soon after waking. Sleep inertia countermeasures have previously been investigated; however, none have successfully dissipated sleep inertia within the first 15 min following waking. During this time, on-call personnel could already be driving, providing advice, or performing other safety-critical tasks. Exercise has not yet been investigated as a sleep inertia countermeasure but has the potential to stimulate the key physiological mechanisms that occur upon waking, including changes in cerebral blood flow, the cortisol awakening response, and increases in core body temperature. Here, we examine these physiological processes and hypothesize how exercise can stimulate them, positioning exercise as an effective sleep inertia countermeasure. We then propose key considerations for research investigating the efficacy of exercise as a sleep inertia countermeasure, including the need to determine the intensity and duration of exercise required to reduce sleep inertia, as well as testing the effectiveness of exercise across a range of conditions in which the severity of sleep inertia may vary. Finally, practical considerations are identified, including the recommendation that qualitative field-based research be conducted with on-call personnel to determine the potential constraints in utilizing exercise as a sleep inertia countermeasure in real-world scenarios

Exercising Caution Upon Waking–Can Exercise Reduce Sleep Inertia?

Sleep inertia, the transitional state of reduced alertness and impaired cognitive performance upon waking, is a safety risk for on-call personnel who can be required to perform critical tasks soon after waking. Sleep inertia countermeasures have previously been investigated; however, none have successfully dissipated sleep inertia within the first 15 min following waking. During this time, on-call personnel could already be driving, providing advice, or performing other safety-critical tasks. Exercise has not yet been investigated as a sleep inertia countermeasure but has the potential to stimulate the key physiological mechanisms that occur upon waking, including changes in cerebral blood flow, the cortisol awakening response, and increases in core body temperature. Here, we examine these physiological processes and hypothesize how exercise can stimulate them, positioning exercise as an effective sleep inertia countermeasure. We then propose key considerations for research investigating the efficacy of exercise as a sleep inertia countermeasure, including the need to determine the intensity and duration of exercise required to reduce sleep inertia, as well as testing the effectiveness of exercise across a range of conditions in which the severity of sleep inertia may vary. Finally, practical considerations are identified, including the recommendation that qualitative field-based research be conducted with on-call personnel to determine the potential constraints in utilizing exercise as a sleep inertia countermeasure in real-world scenarios

Underdiagnosis of mild cognitive impairment: A consequence of ignoring practice effects

INTRODUCTION: Longitudinal testing is necessary to accurately measure cognitive change. However, repeated testing is susceptible to practice effects, which may obscure true cognitive decline and delay detection of mild cognitive impairment (MCI). METHODS: We retested 995 late-middle-aged men in a ∼6-year follow-up of the Vietnam Era Twin Study of Aging. In addition, 170 age-matched replacements were tested for the first time at study wave 2. Group differences were used to calculate practice effects after controlling for attrition effects. MCI diagnoses were generated from practice-adjusted scores. RESULTS: There were significant practice effects on most cognitive domains. Conversion to MCI doubled after correcting for practice effects, from 4.5% to 9%. Importantly, practice effects were present although there were declines in uncorrected scores. DISCUSSION: Accounting for practice effects is critical to early detection of MCI. Declines, when lower than expected, can still indicate practice effects. Replacement participants are needed for accurately assessing disease progression.Published versio

Design and Implementation of a Studio-Based General Chemistry Course

Most students taking general chemistry courses do not intend to pursue careers in chemistry; in fact, they are more likely to end up in positions where they fund, write, or vote for chemical research and policies. Our profession continues to ask how we can teach students scientific reasoning skills and chemical understanding in general chemistry that they are able to take beyond the classroom into their everyday lives. The emerging answer at this university is the studio teaching method, which incorporates the “best teaching and learning practices†recommended by chemical education research within an integrated lecture–lab technology-intensive environment. The design, implementation, and pedagogical rationale of studio general chemistry are described

Deep Chandra Observations of the Compact Starburst Galaxy Henize 2–10: X-Rays from the Massive Black Hole

We present follow-up X-ray observations of the candidate massive black hole (BH) in the nucleus of the low-mass, compact starburst galaxy Henize 2–10. Using new high-resolution observations from the Chandra X-ray Observatory totaling 200 ks in duration, as well as archival Chandraobservations from 2001, we demonstrate the presence of a previously unidentified X-ray point source that is spatially coincident with the known nuclear radio source in Henize 2–10 (i.e., the massive BH). We show that the hard X-ray emission previously identified in the 2001 observation is dominated by a source that is distinct from the nucleus, with the properties expected for a high-mass X-ray binary. The X-ray luminosity of the nuclear source suggests the massive BH is radiating significantly below its Eddington limit (∼10−6 LEdd), and the soft spectrum resembles other weakly accreting massive BHs including Sagittarius A*. Analysis of the X-ray light curve of the nucleus reveals the tentative detection of a ~9 hr periodicity, although additional observations are required to confirm this result. Our study highlights the need for sensitive high-resolution X-ray observations to probe low-level accretion, which is the dominant mode of BH activity throughout the universe

Childhood sleep health and epigenetic age acceleration in late adolescence: Cross-sectional and longitudinal analyses

Aim: Investigate if childhood measures of sleep health are associated with epigenetic age acceleration in late adolescence. Methods: Parent-reported sleep trajectories from age 5 to 17, self-reported sleep problems at age 17, and six measures of epigenetic age acceleration at age 17 were studied in 1192 young Australians from the Raine Study Gen2. Results: There was no evidence for a relationship between the parent-reported sleep trajectories and epigenetic age acceleration (p ≥ 0.17). There was a positive cross-sectional relationship between self-reported sleep problem score and intrinsic epigenetic age acceleration at age 17 (b = 0.14, p = 0.04), which was attenuated after controlling for depressive symptom score at the same age (b = 0.08, p = 0.34). Follow-up analyses suggested this finding may represent greater overtiredness and intrinsic epigenetic age acceleration in adolescents with higher depressive symptoms. Conclusion: There was no evidence for a relationship between self- or parent-reported sleep health and epigenetic age acceleration in late adolescence after adjusting for depressive symptoms. Mental health should be considered as a potential confounding variable in future research on sleep and epigenetic age acceleration, particularly if subjective measures of sleep are used

Time-sequenced Multi-Radio-Frequency Observations of Cygnus X-3 in Flare

Multifrequency observations from the VLA, VLBA and OVRO Millimeter Array of a major radio outburst of Cygnus X-3 in 2001 September are presented, measuring the evolution of the spectrum of the source over three decades in frequency, over a period of six days. Following the peak of the flare, as the intensity declines the high-frequency spectrum at frequency nu steepens from nu^{-0.4} to nu^{-0.6}, after which the spectral index remains at this latter terminal value; a trend previously observed but hitherto not satisfactorily explained. VLBA observations, for the first time, track over several days the expansion of a sequence of knots whose initial diameters are approximately 8 milliarcseconds. The light-crossing time within these plasmons is of the same order as the time-scale over which the spectrum is observed to evolve. We contend that properly accounting for light-travel time effects in and between plasmons which are initially optically thick, but which after expansion become optically thin, explains the key features of the spectral evolution, for example the observed timescale. Using the VLBA images, we have directly measured for the first time the proper motions of individual knots, analysis of which shows a two-sided jet whose axis is precessing. The best-fit jet speed is roughly beta = 0.63 and the precession period is about 5 days, significantly lower than fitted for a previous flare. Extrapolation of the positions of the knots measured by the VLBA back to zero-separation shows this to occur approximately 2.5 days after the detection of the rise in flux density of Cygnus X-3.Comment: 23 pages, 10 figures, accepted by Ap

No excess of mitochondrial DNA deletions within muscle in progressive multiple sclerosis

BACKGROUND: Mitochondrial dysfunction is an established feature of multiple sclerosis (MS). We recently described high levels of mitochondrial DNA (mtDNA) deletions within respiratory enzyme-deficient (lacking mitochondrial respiratory chain complex IV with intact complex II) neurons and choroid plexus epithelial cells in progressive MS. OBJECTIVES: The objective of this paper is to determine whether respiratory enzyme deficiency and mtDNA deletions in MS were in excess of age-related changes within muscle, which, like neurons, are post-mitotic cells that frequently harbour mtDNA deletions with ageing and in disease. METHODS: In progressive MS cases (n=17), known to harbour an excess of mtDNA deletions in the central nervous system (CNS), and controls (n=15), we studied muscle (paraspinal) and explored mitochondria in single fibres. Histochemistry, immunohistochemistry, laser microdissection, real-time polymerase chain reaction (PCR), long-range PCR and sequencing were used to resolve the single muscle fibres. RESULTS: The percentage of respiratory enzyme-deficient muscle fibres, mtDNA deletion level and percentage of muscle fibres harbouring high levels of mtDNA deletions were not significantly different in MS compared with controls. CONCLUSION: Our findings do not provide support to the existence of a diffuse mitochondrial abnormality involving multiple systems in MS. Understanding the cause(s) of the CNS mitochondrial dysfunction in progressive MS remains a research priority