Honey as a potent natural supplement for diverse human ailments

Abstract The use of natural honey (NH) as a medicinal agent is associated with a vast range of health benefits and therapeutic promises. The tradition of using honey as a potent food supplementation and medicinal component exist in several countries cutting across traditions and civilizations. This review revisits the wide spectrum of medicinal properties that are associated with honey in the light of modern research and attempts to impart the much needed data required to provide this natural food the status of evidence based medicine. Subjects as diverse as diabetes, cardiology and ophthalmology were covered where beneficial medical properties of honey has been demonstrated and the review was concluded by identifying few safety aspects that are required to be known while using natural, unprocessed honey

GHB acid: A rage or reprive

Gamma-hydroxybutyric acid (GHB) is a naturally occurring analog of gamma-aminobutyric acid (GABA) that has been used in research and clinical medicine for many years. GHB was used clinically as an anesthetic in the 1960s but was withdrawn due to side effects that included seizures and coma. GHB has been implicated in a number of crime types; most notably in drug-facilitated sexual assault. GHB is abused by three main groups of users: Body builders who use the substance believing that it stimulated the release of growth hormone; sexual predators who covertly administer the drug for its sedative and amnesic effects and club-goers (rave parties) who take the drug for its euphoric effects. The short-lived hypnotic effects, relative safety and widespread availability of the drug have made it particularly well suited to this role. The drug has an addictive potential if used for long term. The primary effects of GHB use are those of a CNS depressant and therefore range from relaxation, to euphoria, confusion, amnesia, hallucinations, and coma. Despite the increased regulation, GHB remains widely available through the Internet where one can easily purchase the necessary reagents as well as recipes for home production. There are reports of patients being unresponsive to painful stimuli and cases of oral self-mutilations linked to the abuse of GHB, though quiet rare. Such cases should remind odontologists that intra-oral lesions may be the result of self-mutilation either due to mental illness or altered states caused by the use of prescription or non-prescription drugs

Fibrolipoma - A Rare Intraoral Tumor: A Case Report

Lipomas are the most common benign mesenchymal tumors, developing in any location where fat is normally present. They develop mostly in the subcutaneous tissues but also could develop in deeper tissues. These most commonly occur in the fifth or sixth decade of life, are multiple in 5% of patients and are uncommon in children. However in the oral cavity this is a relatively rare tumor. When present in the oral cavity these lipomas can present with difficulties in speech and mastication. They predominantly affect the buccal mucosa followed by the lip and tongue. We present a case report of a young female patient diagnosed with a fibro-lipoma in the hard palate

Unveiling the Enigma of the Phosphatase and Tensinogen Gene in Cancer and its Potential Role in Oral Cancer- A Narrative Review

Phosphatase and Tensin Homolog (PTEN) is a tumour suppressor gene that plays a vital role in the normal cell cycle. PTEN acts on the cell via the phosphatidyl-inositol-3-kinase pathway which is involved in the process of cell growth, differentiation, migration, and survival. PTEN is most frequently inactivated in human cancers, because of genetic alterations or transcriptional/post-transcriptional modifications. Literature search was done using the keywords “PTEN in cancer” and “PTEN in Oral Cancer” using Pubmed as the database. This article briefly discusses the multiple features of the PTEN gene and its significance in cancer for improving the understanding of the biology of oral carcinogenesis and the potential for future research in this field