871 research outputs found
Dynamic reference point method with probabilistic linguistic information based on the regret theory for public health emergency decision-making
Group emergency decision-making is an uncertain and dynamic
process, in which the decision makers may be bounded rational
and have a risk appetite. To depict the vague qualitative assessments, the probabilistic linguistic term sets are employed to
express the perceptions of decision makers. First, considering the
regret-aversion of the decision makersâ psychological characteristic, the value function and the regret-rejoice function in the regret
theory are modified to adapt the probabilistic linguistic information. Second, the definition and aggregation operators of the
probabilistic linguistic time variable are proposed to describe and
aggregate the dynamic decision information. Third, the probabilistic linguistic models based on the dynamic reference point
method and the regret theory are studied to maximise the
expectation-levels of alternatives at the relative time point. The
proposed method is applied to select the optimal response strategy for the outbreak of COVID-19 in China. Finally, the comparative analysis is designed to verify the applicability and
reasonability of the proposed method
MEMS Biomimetic Acoustic Pressure Gradient Sensitive Structure for Sound Source Localization
The parasitoid fly Ormia ochracea shows an astonishing localization ability with its tiny hearing organ. A novel MEMS biomimetic acoustic pressure gradient sensitive structure was designed and fabricated by mimicking the mechanically coupled tympana of the fly. Firstly, the analytic representation formulas of the resultant force and resultant moment of the incoming plane wave acting on the structure were derived. After that, structure modal analysis was performed and the results show that the structure has out-of-phase and in-phase vibration modes, and the corresponding eigenfrequency is decided by the stiffness of vertical torsional beam and horizontal beam respectively. Acoustic-structural coupled analysis was performed and the results show that phase difference and amplitude difference between the responses of the two square diaphragms of the sensitive structure are effectively enlarged through mechanical coupling beam. The phase difference and amplitude difference increase with increasing incident angle and can be used to distinguish the direction of sound arrival. At last, the fabrication process and results of the device is also presented
Population genetics analysis of the black rockfish <em>Sebastes schlegelii</em> in Northern China based on 2b-RAD simplified genome sequencing
The black rockfish Sebastes schlegelii is an important fishery species in Japan, South Korea, and China. Overfishing has severely depleted the natural resources of S. schlegelii in recent years, leading to the initiation of programs aimed at enhancing fish stock. However, the genetic structure of northern populations remains elusive, posing challenges in collecting and preserving germplasm resources. In this study, a total of 191 S. schlegelii individuals from seven populations, including one cultured population (Changdao: CDYZ) and six wild populations (Lianyungang: LYG; Qingdao: QD; Weihai: WH; Changdao: CDYS; Beidaihe: BDH) sequenced by 2b-RAD method and their population genetics was analyzed using 27,064 SNPs obtained. The results indicated low genetic diversity in both wild and cultured populations (PIC Ho: 0.174-0.273, He: 0.173-0.234), with the cultured population exhibiting higher diversity than the wild ones. Moderate genetic differentiation existed between the cultured population and six wild populations (0.05 Fst Fst Nm > 1). This study provides a theoretical basis for conserving and rationalizing germplasm resources for S. schlegelii
Pyrimido[4,5â d ]pyrimidinâ4(1 H )âone Derivatives as Selective Inhibitors of EGFR Threonine 790 to Methionine 790 (T790M) Mutants
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/99673/1/8545_ftp.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/99673/2/ange_201302313_sm_miscellaneous_information.pd
Pyrimido[4,5â d ]pyrimidinâ4(1 H )âone Derivatives as Selective Inhibitors of EGFR Threonine 790 to Methionine 790 (T790M) Mutants
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/99681/1/8387_ftp.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/99681/2/anie_201302313_sm_miscellaneous_information.pd
pH-Induced Conformational Changes in the Soluble Manganese-Stabilizing Protein of Photosystem II â
Tunable Interband Transitions in Twisted h-BN/Graphene Heterostructures
In twisted h-BN/graphene heterostructures, the complex electronic properties
of the fast-traveling electron gas in graphene are usually considered to be
fully revealed. However, the randomly twisted heterostructures may also have
unexpected transition behaviors, which may influence the device performance.
Here, we study the twist angle-dependent coupling effects of h-BN/graphene
heterostructures using monochromatic electron energy loss spectroscopy. We find
that the moir\'e potentials alter the band structure of graphene, resulting in
a redshift of the intralayer transition at the M-point, which becomes more
pronounced up to 0.25 eV with increasing twist angle. Furthermore, the twisting
of the Brillouin zone of h-BN relative to the graphene M-point leads to tunable
vertical transition energies in the range of 5.1-5.6 eV. Our findings indicate
that twist-coupling effects of van der Waals heterostructures should be
carefully considered in device fabrications, and the continuously tunable
interband transitions through the twist angle can serve as a new degree of
freedom to design optoelectrical devices
A recombinant avian antibody against VP2 of infectious bursal disease virus protects chicken from viral infection
ăAbstractăA stable cell-line was established that expressed the recombinant avian antibody (rAb) against the infectious bursal disease virus (IBDV). rAb exhibited neutralization activity to IBDV-B87 strain in DF1 cells. The minimum rAb concentration required for inhibition of the cytopathic effect (CPE) was 1.563 ÎŒg/mL. To test the efficacy of rAb, a 168-h cohabitation challenge experiment was performed to transmit the disease from the chickens challenged with vvIBDV (HLJ0504 strain) to three test groups of chickens, i.e. (1) chickens treated with rAb, (2) chickens treated with yolk antibody, and (3) non-treatment chickens. The survival rates of chickens treated with rAb, yolk antibody and without treatment were 73%, 67% and 20%, respectively. Another batch of chickens was challenged with IBDV (BC6/85 strain) and then injected with rAb (1.0 mg/kg) 6, 24 and 36 h post-challenge. Non-treatment chickens had 100% morbidity, whereas those administered with rAb exhibited only 20% morbidity. Morbidity was evaluated using clinical indicators and bursal histopathological section. This study provides a new approach to treating IBDV and the rAb represents a promising candidate for this IBDV therapy.This research was supported by Heilongjiang province project of applied technology research and development (2013GC13C105) and The National Natural Science Fund biologic science base improve program of research training and capacity (J1210069/J0124)
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