1 research outputs found
DNA-Decorated Two-Dimensional Crystalline Nanosheets
Design and synthesis of high aspect
ratio 2D nanosheets with surface
having ultradense array of information-rich molecule such as DNA is
extremely challenging. Herein, we report a universal strategy based
on amphiphilicity-driven self-assembly
for the crafting of high aspect ratio, 2D sheets that are densely
surface-decorated with DNA. Microscopy and X-ray analyses have shown
that the sheets are crystalline. The most unique feature of the sheets
is DNA-directed surface addressability, which is demonstrated through
the decoration of either faces of the sheet with gold nanoparticles
through sequence-specific DNA hybridization. Our results suggest that
this design strategy can be applied as a general approach for the
synthesis of DNA decorated high aspect ratio sheets, which may find
potential applications in materials science, drug delivery, and nanoelectronics